- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Ophthalmology and Eye Disorders
- Photoreceptor and optogenetics research
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Visual perception and processing mechanisms
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Cerebral Venous Sinus Thrombosis
- Botulinum Toxin and Related Neurological Disorders
- Ocular and Laser Science Research
- Vestibular and auditory disorders
- Ocular Diseases and Behçet’s Syndrome
- Drug-Induced Ocular Toxicity
- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- Retinal and Macular Surgery
- Vascular Malformations Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Autoimmune Neurological Disorders and Treatments
- Trigeminal Neuralgia and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
University of Basel
2015-2025
University Hospital of Basel
2016-2025
Universitäre Psychiatrische Kliniken Basel
2014
Hospital Base
2005-2010
Saarland University
1992-2006
Institute of Molecular and Clinical Ophthalmology Basel
2006
He Eye Hospital
2005
Universitätsaugenklinik Magdeburg
2000-2004
STZ eyetrial
1999-2003
Universitäts-Augenklinik Bonn
2001-2003
The clinical multifocal electroretinogram (mfERG) is an electrophysiological test of local retinal function. With this technique, many ERG responses, typically 61 or 103, are recorded from the cone-driven retina under light-adapted conditions. This document specifies guidelines for performance test. It also provides detailed guidance on technical and practical issues, as well reporting results. main objective to promote consistent quality mfERG testing within among centers. These 2007...
Abstract Background The global incidence of high myopia is increasing, with projections indicating a rise from 3 to 10% the population by 2050. Effective treatment options exist reduce progression, but their success contingent on patient adherence. This study assesses impact changes in treating physicians adherence therapy control progression. Patients and Methods retrospective observational analyzed data Myopia Clinic at University Eye Hospital Basel 2020 2023. Adherence rates were compared...
Abstract Background Surgical methods to join extraocular muscles are now often used reduce the risk of scleral perforation in strabismus surgery, but published results indicate that outcome is highly variable. We therefore wanted assess whether conventional horizontal surgery still a valid option high myopia. Patients and Methods A retrospective chart review patients with myopia, defined as spherical equivalent ≥ − 6.0 D at least one eye, who had undergone was performed. Exotropic angles...
Abstract Background Dose effect (DE) of strabismus surgery is thought to decrease with increasing axial length (AL), and it has been suggested that this may be more important in hyperopes over + 2 D. Here, we analyse the influence AL on DE horizontal regard its clinical relevance. Methods Retrospective chart analysis patients who had undergone between 2020 2023. Statistical analysis: descriptive ANOVA (R 4.1.2). Results There were 65 (34 male 31 female) included; mean age: 18.0 years (range...
OBJECTIVE Craniosynostosis is ideally treated within the 1st year of life to correct physical deformity, achieve optimal aesthetic head shape, and facilitate normal neurocognitive development. While objective assessments have been widely studied, limited reports on long-term parent-reported outcomes (PROs) exist. The authors herein report follow-up after open midline strip craniectomy with barrel stave osteotomies (BSOs) occipital release nonsyndromic sagittal craniosynostosis (SC),...
Summary Background Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome with symptoms of night blindness, light sensations, visual loss, defect in fields, and reduced b-waves the electroretinogram. Patients MAR often suffer from sudden onset ocular that are believed to result antibody production against melanoma-associated antigens cross-react corresponding epitopes on retinal depolarizing bipolar cells. Objectives To correlate frequency subclinical suggestive melanoma patients...
Purpose . To compare two different spectral-domain optical coherence tomography (OCT) systems in regard to full macular thickness (MT) and ganglion cell layer-inner plexiform layer (GCIPL) measures structure-function correlation when compared standard automated perimetry (SAP). Methods Seventeen primary open angle glaucoma patients 16 controls (one eye per subject) were enrolled. MT GCIPL thicknesses measured by Cirrus Spectralis OCTs. Octopus Perimeter 101 (G2 protocol) reports sensitivity...
<i>Purpose:</i> To analyze a multiflash multifocal electroretinogram in 20 patients with open-angle glaucoma (OAG). <i>Methods:</i> The stimulation sequence consisted of binary m-sequence (L<sub>max</sub> 200 cd/m<sup>2</sup>, L<sub>min</sub> <1 cd/m<sup>2</sup>). Each stimulus was followed by three global flashes (luminance: 400 cd/m<sup>2</sup>) at an interval 26 ms. <i>Results:</i> presence...
<i>Purpose:</i> It was the aim of this study to evaluate antiphospholipid antibodies (APA), i.e. lupus anticoagulants (LA) and anticardiolipin (ACA) IgG IgM, in ophthalmic occlusive disease. <i>Methods:</i> Over a 3.5-year period, APA were evaluated 368 patients. <i>Results:</i> Eighty-six patients (23.4%), compared 5% general population, tested positive for APA. did not differ significantly between with venous (20.6%) or arterial (25.5%) This included 93...
To further improve analysis of the two-flash multifocal electroretinogram (2F-mfERG) in glaucoma regard to structure-function analysis, using discrete wavelet transform (DWT) analysis.Sixty subjects [35 controls and 25 primary open-angle (POAG)] underwent 2F-mfERG. Responses were analyzed with DWT. The DWT level that could best separate POAG from was compared root-mean-square (RMS) calculations previously used In a subgroup correlation assessed between DWT, optical coherence tomography...
The orbicularis oculi are the sphincter muscles of eyelids and involved in modulating facial expression. They differ from both limb extraocular (EOMs) their histology biochemistry. Weakness is a feature neuromuscular disorders affecting junction, weakness ptosis have also been described patients with mutations ryanodine receptor gene. Here, we investigate human find that they functionally more similar to quadriceps than EOMs terms excitation–contraction coupling components. In particular, do...