A5021489199- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
- Neuroinflammation and Neurodegeneration Mechanisms
- Neural dynamics and brain function
- Stress Responses and Cortisol
- Photoreceptor and optogenetics research
- Receptor Mechanisms and Signaling
- Neuroscience and Neural Engineering
City University of Hong Kong
2023-2025
Chinese Academy of Sciences
2025
City University of Hong Kong, Shenzhen Research Institute
2023-2024
High-frequency stimulation (HFS)-induced long-term potentiation (LTP) is generally regarded as a homosynaptic Hebbian-type LTP, where synaptic changes are thought to occur at the synapses that project from site and terminate onto neurons recording site. In this study, we first investigated HFS-induced LTP on urethane-anesthetized rats found cortical HFS enhances neural responses through strengthening of local connectivity with nearby site, rather than This enhanced leads increased output...
Long-term potentiation (LTP), which underlies learning and memory, can be induced by high-frequency electrical stimulation (HFS or HFES) is thought to occur at the synapses of efferent projection. Here, contralateral connectivity in mice auditory cortex was investigated reveal fundamental corticocortical connection properties. After HFES, plasticity not observed terminal recording site. The optogenetic HFS site interhemispheric cortical projections could induce LTP, but HFES LTP. Our...
Abstract The thalamocortical pathway exhibits neuroplasticity not only during the critical period but also in adulthood. Here, we aimed to investigate modulation of age-dependent plasticity by cholecystokinin (CCK). Our findings revealed expression CCK neurons, and high-frequency stimulation (HFS) elicited release auditory cortex (ACx), as evidenced sensor. HFS medial geniculate body (MGB) induced long-term potentiation (LTP) wildtype young adult mice. However, knockdown Cck MGB neurons or...
The thalamocortical pathway exhibits neuroplasticity not only during the critical period but also in adulthood. Here, we aimed to investigate modulation of age-dependent plasticity by cholecystokinin (CCK). Our findings revealed expression CCK neurons, and high-frequency stimulation (HFS) elicited release auditory cortex (ACx), as evidenced sensor. HFS medial geniculate body (MGB) induced long-term potentiation (LTP) wildtype young adult mice. However, knockdown Cck MGB neurons or blockade...
The thalamocortical pathway exhibits neuroplasticity not only during the critical period but also in adulthood. Here, we aimed to investigate modulation of age-dependent plasticity by cholecystokinin (CCK). Our findings revealed expression CCK neurons, and high-frequency stimulation (HFS) elicited release auditory cortex (ACx), as evidenced sensor. HFS medial geniculate body (MGB) induced long-term potentiation (LTP) wildtype young adult mice. However, knockdown Cck MGB neurons or blockade...