Chun Xie

ORCID: 0000-0003-4083-2891
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About
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Research Areas
  • Eating Disorders and Behaviors
  • Obesity, Physical Activity, Diet
  • Neural and Behavioral Psychology Studies
  • Ion channel regulation and function
  • Neuroscience and Neuropharmacology Research
  • Autoimmune Neurological Disorders and Treatments
  • Behavioral Health and Interventions
  • Heart Rate Variability and Autonomic Control
  • Sport Psychology and Performance
  • Cardiovascular and exercise physiology
  • Biochemical Analysis and Sensing Techniques
  • Membrane-based Ion Separation Techniques
  • Motivation and Self-Concept in Sports
  • EEG and Brain-Computer Interfaces
  • Pharmacology and Obesity Treatment
  • Visual perception and processing mechanisms
  • Sports Performance and Training
  • Anesthesia and Neurotoxicity Research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Ideological and Political Education
  • Functional Brain Connectivity Studies
  • Sports Analytics and Performance
  • Membrane Separation Technologies
  • Transcranial Magnetic Stimulation Studies
  • Amino Acid Enzymes and Metabolism

Center for Excellence in Brain Science and Intelligence Technology
2018-2025

Chinese Academy of Sciences
2018-2025

Shanghai Jiao Tong University
2022-2025

Shanghai University of Sport
2017-2021

Guangzhou Institute of Advanced Technology
2021

Shanghai Institutes for Biological Sciences
2018-2019

Yan'an University
2004

Backgrounds and Objectives: Obesity presents a significant global public health challenge is associated with declines in both general food-related inhibitory control, crucial for maintaining healthy weight preventing obesity progression. An increasing body of research suggests that acute aerobic exercise may improve function. However, the effects underlying mechanisms on inhibition obese adults remain unclear. This study aimed to explore potential impacts neuroelectronic single session at...

10.3390/brainsci15010059 article EN cc-by Brain Sciences 2025-01-10

The cerebral cortex and hippocampus are crucial brain regions for learning memory, which depend on activity-induced synaptic plasticity involving N-methyl-ᴅ-aspartate receptors (NMDARs). However, subunit assembly molecular architecture of endogenous NMDARs (eNMDARs) in the remain elusive. Using conformation- subunit-dependent antibodies, we purified eNMDARs from adult rat hippocampus. Three major subtypes GluN1-N2A-N2B, GluN1-N2B, GluN1-N2A were resolved by cryoelectron microscopy (cryo-EM)...

10.1016/j.cell.2025.01.004 article EN cc-by Cell 2025-01-01

N-methyl-D-aspartate (NMDA) receptors are critical for synaptic development and plasticity. While glutamate is the primary agonist, protons can modulate NMDA receptor activity at synapses during vesicle exocytosis by mechanisms that unknown. We used cryo-electron microscopy to solve structures of human GluN1-GluN2A pH 7.8 6.3. Our demonstrate proton sensor predominantly resides in N-terminal domain (NTD) GluN2A subunit reveal allosteric coupling mechanism between channel gate. Under high-pH...

10.1016/j.celrep.2018.11.071 article EN cc-by-nc-nd Cell Reports 2018-12-01

To gain more insight into why adolescents exercise, based on Schwartz's personal values model and self-determination theory, this study examined whether affect leisure-time exercise behavior their underlying mechanisms. Five hundred twenty-two participants (193 Females 329 Males; Mage = 19.32, SD 1.02) in China were included. Structural equation modeling was used to examine the mediating moderating effect. The results indicated that security-personal can predict identified regulation,...

10.1002/pchj.70012 article EN cc-by PsyCh Journal 2025-03-29

Antibodies against N-methyl-d-aspartate receptors (NMDARs) are most frequently detected in persons with autoimmune encephalitis (AE) and used as diagnostic biomarkers. Elucidating the structural basis of monoclonal antibody (mAb) binding to NMDARs would facilitate development targeted therapy for AE. Here, we reconstructed nanodiscs containing green fluorescent protein-fused label sort individual immune B cells from AE further cloned identified mAbs NMDARs. This allowed cryo-electron...

10.1038/s41594-024-01387-3 article EN cc-by-nc-nd Nature Structural & Molecular Biology 2024-09-03

Executive control, the ability to regulate execution of a goal-directed task, is an important element in athlete's skill set. Although previous studies have shown that executive control athletes better than non-athletes, those were mainly confined conscious control. Many recent suggested can be triggered by presentation visual stimuli without participant's awareness. However, few examined unconscious sports. Thus, present study investigated whether, similar table tennis superior...

10.7717/peerj.6387 article EN cc-by PeerJ 2019-02-05

This study aimed to examine whether a single bout each of high-intensity interval exercise (HIIE) and continuous (HICE) could improve inhibitory functions overweight obese children, which mode was more beneficial. Seventy-two with (26.02 ± 1.05 kg/m

10.3390/ijerph191610401 article EN International Journal of Environmental Research and Public Health 2022-08-21

Objective. The present study examined the effects of Tai Chi exercise on executive functions (EFs) and physical fitness middle-aged adults with depression. Methods. A total 39 depression (Mage = 50.59, SD 7.38) were randomly assigned to group (n 20) or waiting-list control 19). engaged in two 90 min sessions per week for 12 weeks; was asked maintain their usual daily routines weeks. Depression symptoms, EFs (i.e., inhibitory control, planning, working memory, cognitive flexibility),...

10.1155/2022/1589106 article EN Evidence-based Complementary and Alternative Medicine 2022-09-13

Obesity poses a pervasive challenge to global public health, which is linked adverse physical health outcomes and cognitive decline. Cognitive function, particularly food-related plays critical role in sustaining healthy weight mitigating the progression of obesity. The aim this study was investigate behavioral neuroelectronic aspects inhibitory functions young adult males with

10.1016/j.physbeh.2024.114573 article EN cc-by Physiology & Behavior 2024-04-27

The aim of the present study was to examine influence acute high-intensity interval exercise (HIIE) on neural and behavioral measures inhibitory control in young male adults with obesity.The employed a within-subjects design.Sixteen obesity [body mass index (BMI) > 28 kg/m2] were recruited. Reaction time response accuracy Flanker task as well P3 late positive potential (LPP) components event-related (ERP) measured following HIIE sedentary control, counterbalanced order. session consisted 30...

10.3389/fpsyg.2020.01291 article EN cc-by Frontiers in Psychology 2020-06-25

Objective The present study was to determine the effect of a combined exercise and dietary program on cognitive function as well relationship between program-induced weight change alterations. Design applies quasi-experimental design. Methods Fifty-eight adolescents with obese status (body mass index, BMI >28 kg/m 2 ) were assigned either an experiment ( n = 30) or control group 28). Participants in received scheduled specific protocol (two sessions per day, six days week) diet plan for...

10.7717/peerj.3286 article EN cc-by PeerJ 2017-05-16

Although physical activity is associated with better attentional functioning in elderly populations or specific clinical populations, the association between level and attention has been less studied young adult populations. Thus, purpose of this study was to investigate whether positive effects on networks extend adults. In total, 57 college students were recruited assigned one three groups levels (high, moderate, low) based their self-reported exercise. Each participant completed Attention...

10.3390/ijerph19095374 article EN International Journal of Environmental Research and Public Health 2022-04-28

This cross-sectional study compared the physical fitness and mental health status of 140 school-age children who participated in sport-specific training with 180 age-matched peers. All participants were grouped by frequencies extracurricular time into following: (i) high sports frequency group (HFG): three to five times per week ( n = 77, mean [SD] age: 9.60 [0.12] years); (ii) low (LFG): once 63, 9.88 [0.14] (iii) control (CG): maintaining routine life 180, (SD) 9.77(0.09) years). Physical...

10.7717/peerj.10842 article EN cc-by PeerJ 2021-02-02

Purpose Cognitive function, particularly food-related cognition, is critical for maintaining a healthy weight and preventing the acceleration of obesity. High-Intensity Interval Exercise (HIIE) an increasingly popular form exercise has been shown to improve physical fitness cognitive function. However, there limited research on effects underlying mechanisms HIIE general cognition among adults with The aim current study was examine influence single bout young Methods Fifteen men obesity (BMI...

10.1016/j.ijchp.2023.100430 article EN cc-by International Journal of Clinical and Health Psychology 2023-12-20

Many reports have emphasized that unconscious processing demands attention. However, some studies were unable to observe a modulation of attentional load in subliminal visual processing. We proposed the paradoxical phenomena could be explained based on whether mental workload task was involved central executive processes. In two experiments, by combining masked shape discrimination with an N-back task, attention availability for visuomotor decreased as demand increased. observed priming...

10.3389/fpsyg.2022.800781 article EN cc-by Frontiers in Psychology 2022-05-30

The task-preparation processes usually be affected by different factors, such as attentional demands, and skill levels. Researches in sport motor field reported that skilled athletes are characterized intense preparation of stimuli employ highly developed strategies the attention domains, to respond effectively. PURPOSE: To investigate effect level on strategy with varying demands. METHODS: 50 participants were grouped into Elites group (EG, n = 17), Amateur (AG, 16) Control (CG, 17) based...

10.1249/01.mss.0000517703.83126.88 article EN Medicine & Science in Sports & Exercise 2017-05-01
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