A5017093428- Global Health Care Issues
- Advanced Proteomics Techniques and Applications
- Healthcare Policy and Management
- Global Maternal and Child Health
- Nutrition, Health and Food Behavior
- Microfluidic and Capillary Electrophoresis Applications
- Pharmaceutical Economics and Policy
- Global Public Health Policies and Epidemiology
- Child Nutrition and Water Access
- Mass Spectrometry Techniques and Applications
- Primary Care and Health Outcomes
- Vaccine Coverage and Hesitancy
- Analytical chemistry methods development
- Cancer Risks and Factors
- Analytical Chemistry and Sensors
- Gynecological conditions and treatments
- Child Nutrition and Feeding Issues
- Global Cancer Incidence and Screening
- Reproductive Biology and Fertility
- Human Health and Disease
- Adolescent and Pediatric Healthcare
- Health Promotion and Cardiovascular Prevention
- Reproductive System and Pregnancy
- Obesity, Physical Activity, Diet
- Acute Ischemic Stroke Management
Jiangxi Provincial Cancer Hospital
2022-2024
North China University of Science and Technology
2024
Nanchang University
2009-2023
World Health Organization Regional Office for the Western Pacific
2018
Organisation de Coopération et de Développement Economiques
2018
Maternal and Child Health Hospital of Sichuan Province
2018
Los Alamos National Laboratory
2017-2018
Reproductive Science Center
2011
California Institute for Biomedical Research
2004
University of Maryland, College Park
2000-2003
An integrated platform is presented for rapid and sensitive protein identification by on-line digestion analysis of digested proteins using electrospray ionization mass spectrometry or transient capillary isotachophoresis/capillary zone electrophoresis with detection. A miniaturized membrane reactor constructed fabricating the microfluidic channels on a poly(dimethylsiloxane) substrate coupling microfluidics to poly(vinylidene fluoride) porous adsorbed trypsin. On basis he large surface...
Premature rupture of membranes (PROM) is a common pregnancy complication that frequently results in maternal and perinatal morbidity. The present methods for diagnosing PROM do not satisfy clinical requirements. study aimed to examine the proteome profile amniotic fluid (AF) plasma, screen unique proteins AF, evaluate their diagnostic value PROM. profiles AF plasma were examined via liquid chromatography coupled with tandem mass spectrometry‑based proteomic techniques. protein expression...
A sensitive and specific liquid chromatography-electrospray ionization-mass spectrometry method for the identification quantification of pentoxyverine citrate guaifenesin in human plasma has been developed. After extraction from samples by ethyl acetate, internal standard analytes were separated high-performance chromatographic on a Shim-pack VP-ODS C(18) column (150 x 2.0 mm) using mobile phase consisting (methanol) B (0.4% glacial acetic acid 4 mmol/L ammonium acetate) (A:B, 43 : 57)....
There is growing evidence that the KDM5 family of histone demethylases plays a causal role in human cancer. However, few studies have been reported on endometrial carcinoma (EC). Moreover, it was found there some correlation between and FOXO1 EC. The current study performed to explore expressions KDM5A, KDM5B, endometrioid adenocarcinoma detected by immunohistochemistry; paracancer endometrium, simple hyperplastic normal endometrium were used as control groups possible diagnostic value KDM5A...
Capillary isoelectric focusing (CIEF) involves the use of entire capillary filled with a mixture containing protein/peptide analytes and carrier ampholytes. Thus, preparative capabilities CIEF are inherently greater than most capillary-based electrokinetic separation techniques. To further increase sample loading and, therefore, concentrations focused analytes, dynamic approach, which is based on injection proteins/peptides from solution reservoir, demonstrated using low pI protein...
Bacterial persistence, known as noninherited antibacterial resistance, is a factor contributing to the establishment of long-lasting chronic bacterial infections. In this study, we examined ability nicotinamide (NA) potentiate activity different classes antibiotics against Burkholderia thailandensis persister cells.
A gel protein capillary extraction apparatus is developed and demonstrated for its rapid effective transfer of SDS−protein complexes from polyacrylamide to a fused-silica capillary. The small dimensions columns permit the application high voltages achieving proteins. Furthermore, capillaries are internally coated with elimination electroosmotic pumping adsorption onto wall. extracted proteins present in highly concentrated solution plug as result field amplification sample stacking during...
Acute ischemic cerebrovascular disease (AICD) poses a severe threat to human health, characterized by high incidence and disability rates. Western medicine currently offers multiple treatment methods, such as thrombolysis, anticoagulation, cerebral circulation improvement, while traditional Chinese demonstrates unique advantages in herbal prescriptions, proprietary medicines, acupuncture, massage therapies. Integrative approaches combining have become widespread clinical practice, yet...
Abstract An electronic protein transfer technique is described for achieving the rapid and efficient recovery of sodium dodecyl sulfate (SDS)‐protein complexes from polyacrylamide gels. This process involves use small‐dimension capillaries in physical contact with a resolved band within gel, providing large potential drop high electric field strength at capillary/gel interface. Several factors controlling transfer, including applied strength, electrophoresis buffer concentration, capillary...
Background: Hepatocellular carcinoma (HCC) represents a major cause of cancer death, but the molecular mechanism for its development has not been well characterized yet. Long non-coding RNAs (lncRNAs) have reported to be involved in wide range biological processes due their roles as oncogenes or tumor suppressor genes.Methods: The present study aimed elucidate role LINC00324 HCC through interaction with Fas ligand (FasL). Initially, microarray-based gene expression profiling was employed...
This study aimed to develop an animal model of pathologic regeneration intrauterine adhesions (IUA) and assess the impact ITGB3 PPIF plasmid construction on offspring rats with IUA. Thirty female SD were divided into experimental group a control group. In group, rats’ left right endometrium underwent mild severe mechanical damage using self-made curette. The sham operation without endometrial injury. At various time points after surgery, uteruses collected for analysis. Immunohistochemical...