A5071384354- Advanced Proteomics Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Metabolomics and Mass Spectrometry Studies
- Circular RNAs in diseases
- Phonetics and Phonology Research
- Viral-associated cancers and disorders
- Remote Sensing and LiDAR Applications
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Immunotherapy and Immune Responses
- Memory Processes and Influences
- Microfluidic and Bio-sensing Technologies
- T-cell and B-cell Immunology
- Bacillus and Francisella bacterial research
- Memory and Neural Mechanisms
- Medical Imaging Techniques and Applications
- MicroRNA in disease regulation
- Ultrasound Imaging and Elastography
- Neuroscience and Music Perception
- Flow Measurement and Analysis
- Plant biochemistry and biosynthesis
- Insect Resistance and Genetics
- Plant Virus Research Studies
- Gaze Tracking and Assistive Technology
Wenzhou Vocational College of Science and Technology
2024-2025
Hohai University
2025
Peking University First Hospital
2022-2024
Peking University
2022-2024
University of South China
2021-2023
Hebei University of Science and Technology
2023
Guiyang Medical University
2023
South China Agricultural University
2023
Ludong University
2022
China University of Geosciences
2022
Abstract Motivation: Comparing two or more complex protein mixtures using liquid chromatography mass spectrometry (LC-MS) requires multiple analysis steps to locate and quantitate natural peptides within a single experiment align normalize findings across experiments. Results: We describe msInspect, an open-source application comprising algorithms visualization tools for the of LC-MS experimental measurements. The platform integrates novel detecting signatures measurement combines...
Abstract Background Francisella tularensis subspecies and holarctica are pathogenic to humans, whereas the two other subspecies, novicida mediasiatica , rarely cause disease. To uncover factors that allow be we compared their genome sequences with sequence of U112, which is nonpathogenic humans. Results Comparison genomes human strains U112 identifies genes specific reveals pseudogenes previously were unidentified. In addition, this analysis provides a coarse chronology evolutionary events...
An integrated proteome concentration/separation approach involving on-line combination of capillary isoelectric focusing (CIEF) with reversed-phase liquid chromatography (CRPLC) is developed for providing significant analyte concentration and extremely high resolving power toward protein peptide mixtures. Upon completion focusing, the self-sharpening effect greatly restricts diffusion contributes to stacking in narrowly focused bands a factor approximately 240. In addition CIEF as first...
A miniaturized trypsin membrane reactor housed inside a commonly used capillary fitting is developed and demonstrated for enabling rapid sensitive protein identification by on-line proteolytic digestion analysis of digests using nano-ESI-MS MALDI-MS. The design assembly the fitting-based are straightforward highly robust, without need expensive fabrication technology procedures. resultant can also be further concentrated resolved reversed-phase liquid chromatography or transient...
The complexity and diversity of buildings make it challenging to extract low-level high-level features with strong feature representation by using deep neural networks in building extraction tasks. Meanwhile, network-based methods have many network parameters, which take up a lot memory time training testing. We propose novel fully convolutional called the Context Feature Enhancement Network (CFENet) address these issues. CFENet comprises three modules: spatial fusion module, focus...
On-line combination of capillary isoelectric focusing (CIEF) with reversed-phase liquid chromatography (CRPLC) is developed using a microinjector as the interface for performing two-dimensional (2-D) protein/peptide separations complex protein mixtures. The effect CIEF not only contributes to high-resolution separation, but also may permit analysis low-abundance proteins typical concentration factor 50–100 times. preparative capabilities are much larger than most capillary-based...
Soft wearable robots have the potential in assisting human movement and augmenting capabilities for a variety of applications, but design process these often encounters issues efficiency creativity. To fill voids, this study explored GAN-based deep learning methodology, computational advantage StyleGAN3 collaborative utilities such as Google Colab. The method used was training GAN model with 924 images dataset then using satisfaction survey to rate output. In terms results – average score...
This study evaluates and compares ChatGPT-4.0, Gemini Pro 1.5(0801), Claude 3 Opus, Qwen 2.0 72B in answering dental implant questions. The aim is to help doctors underserved areas choose the best LLMs(Large Language Model) for their procedures, improving care accessibility clinical decision-making. Two specialists with over twenty years of experience evaluated models. Questions were categorized into simple true/false, complex short-answer, real-life case analyses. Performance was measured...
Abstract We obtained insight into normal lung function by proteome analysis of bronchoalveolar lavage fluid (BALF) from six human subjects using a “Lyse‐N‐Go' shotgun proteomic protocol. Intra‐sample variation was calculated three different label‐free methods, (i) protein sequence coverage; (ii) peptide spectral counts and (iii) single‐ion current areas (PICA), which generates expression data summation the area under curve for given trace then adding values all peptides that same parent...
Understanding the role of social capital is crucial to cope with cooperation dilemma forest conservation. This study examined impact rural households' on conservation behaviors based 669 household data around 17 giant panda Nature Reserves (NRs) in Shaanxi Province and Sichuan Province, China. Probit model Ordered were used, results show that: (1) Social plays a behaviors; particular, it makes up for formal institutions surrounding NRs. (2) trust core capital. It positively affects...
Abstract BACKGROUND Dicer1 plays a crucial role in regulating the development and reproduction of insects. Knockout causes pupal deformity, low eclosion fecundity Plutella xylostella , but mechanism behind this phenomenon is not clear. This study aims to identify differentially‐expressed genes miRNAs ‐knockout strain (Δ PxDcr‐1 ) assess their impact on P. . RESULTS The knockout affected expression including adipokinetic hormone/corazonin‐related peptide receptor ( PxACPR ). was upregulated,...
Lycopene, the red pigment of tomatoes, is a carotenoid with potent antioxidant properties. Although lycopene might function as prostate cancer chemoprevention agent, little known about its effects at cellular level. To define general changes induced by treatment cells lycopene, and to gain insights into possible properties we investigated in protein expression after human LNCaP cells. The high throughput proteomics data were then visualized analyzed novel biological pathway modeling...
Acetaminophen-induced liver toxicity is the most frequent precipitating cause of acute failure and transplant, but contemporary medical practice has mainly focused on patient management after a injury been induced. An integrative genetic, transcriptional, two-dimensional NMR-based metabolomic analysis performed using multiple inbred mouse strains, along with knowledge-based filtering these data, identified betaine-homocysteine methyltransferase 2 ( Bhmt2 ) as diet-dependent genetic factor...
Abstract Background Plutella xylostella is a devastating agricultural insect pest of cruciferous plants, including crops. Plant‐mediated RNA interference (RNAi) currently being developed for plant protection. In this study, we investigated the response P. exposed to transgenic Arabidopsis thaliana plants that expressed double‐stranded (dsRNA) targeting genes arginine kinase ( PxAK ) and integrin β 1 subunit Pxβ ). RESULTS Transgenic producing dsRNAs 384‐bp fragment (ds AK plants), 497‐bp 881...
Self-attention networks have revolutionized the field of natural language processing and also made impressive progress in image analysis tasks. Corrnet3D proposes idea first obtaining point cloud correspondence registration. Inspired by these successes, we propose an unsupervised network for non-rigid registration, namely NrtNet, which is using a transformer large deformation Specifically, NrtNet consists feature extraction module, matrix generation reconstruction module. Feeding pair...
Capillary isoelectric focusing (CIEF) involves the use of entire capillary filled with a mixture containing protein/peptide analytes and carrier ampholytes. Thus, preparative capabilities CIEF are inherently greater than most capillary-based electrokinetic separation techniques. To further increase sample loading and, therefore, concentrations focused analytes, dynamic approach, which is based on injection proteins/peptides from solution reservoir, demonstrated using low pI protein...
The 1310 Haloarcula marismortui proteins identified from mid-log and late-log phase soluble membrane proteomes were analyzed in metabolic cellular process networks to predict the available systems fluctuations upon environmental stresses. When connected reactions with examined, availability of a number pathways highly amino acid network revealed. Quantitative spectral count analyses suggested 300 or more might have expression changes phase. Among these, integrative indicated approximately...