A5066892607- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Gene Regulatory Network Analysis
- Plant nutrient uptake and metabolism
- Plant Parasitism and Resistance
- Allelopathy and phytotoxic interactions
- CRISPR and Genetic Engineering
- Calcium signaling and nucleotide metabolism
- Bioactive Compounds and Antitumor Agents
- Seed Germination and Physiology
- Polysaccharides and Plant Cell Walls
- Plant tissue culture and regeneration
- Plant-Microbe Interactions and Immunity
- Plant and animal studies
Hebrew University of Jerusalem
2016-2023
Arabidopsis (Arabidopsis thaliana) SPINDLY (SPY) is a putative serine and threonine O-linked N-acetylglucosamine transferase (OGT). While SPY has been shown to suppress gibberellin signaling promote cytokinin (CK) responses, its catalytic OGT activity was never demonstrated effect on protein fate not known. We previously showed that interacts physically functionally with TCP14 TCP15 CK responses. Here, we aimed identify how regulates TCP14/15 activities these TCPs show required for...
Significance Abscisic acid (ABA) is a phytohormone that plants utilize to coordinate responses abiotic stress, modulate seed dormancy, and central plant development in several contexts. Chemicals activate or block ABA signaling are useful as research tools potential agrochemical leads. Many successes have been reported for activators (agonists), but existing blockers (antagonists) limited by modest vivo activity. Here we report antabactin (ANT), potent blocker developed using “click...
Abiotic stresses have severe detrimental effects on agricultural productivity worldwide. Abscisic acid (ABA) levels rise in response to abiotic stresses, and play a role coordinating physiological responses. ABA elicits its by binding family of soluble receptors, increasing affinity the receptors type 2C phosphatases (PP2Cs) leading phosphatase inhibition. In current study, we conducted comprehensive analysis signaling pathway cereal model grass Brachypodium distachyon. The genome encodes 10...
Abscisic acid (ABA) is best known for regulating the responses to abiotic stressors. Thus, applications of ABA signaling pathways are considered promising targets securing yield under stress. levels rise in response stress, mounting physiological and metabolic that promote plant survival unfavorable conditions. elicits its effects by binding a family soluble receptors found monomeric dimeric states, differing their affinity co-receptors. However, vivo significance biochemical differences...
Developing sensory modules for specific molecules of interest represents a fundamental challenge in synthetic biology and its applications. A somewhat generalizable approach this is demonstrated here by evolving naturally occurring chemically induced heterodimer into genetically encoded sensor herbicides. The interaction between PYRABACTIN-RESISTANT-like receptors type-2C protein phosphatases abscisic acid─a small-molecule hormone plants. We considered acid as potential scaffold the...
Abscisic acid (ABA) receptors belong to the START domain superfamily, which encompasses ligand-binding proteins present in all kingdoms of life. contain a central binding pocket that, depending on protein, can couple ligand catalytic, transport or signaling functions. In Arabidopsis, best characterized are 14 PYR/PYL/RCAR ABA receptors, while other members superfamily do not have assigned ligands. To address this, we used affinity purification biotinylated expressed transiently Nicotiana...
Abstract Obligate root holoparasite Phelipanche aegyptiaca is an agricultural pest, which infests its hosts and feeds on the sap, subsequently damaging crop yield quality. Its notoriously viable seed bank may serve as ideal pest control target. The phytohormone abscisic acid (ABA) was shown to regulate P . dormancy following strigolactones germination stimulus. Transcription analysis of signaling components revealed five ABA receptors two co-receptors (PP2C). lower ABA-affinity subfamily III...