A5052747307- Diabetes Management and Research
- Chronic Disease Management Strategies
- Chronic Lymphocytic Leukemia Research
- Nutrition and Health in Aging
- Childhood Cancer Survivors' Quality of Life
- Inflammatory Bowel Disease
- Autoimmune and Inflammatory Disorders Research
- Diabetes Treatment and Management
- Pediatric health and respiratory diseases
- Infant Health and Development
- Tuberculosis Research and Epidemiology
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Body Composition Measurement Techniques
- Gastric Cancer Management and Outcomes
- Treatment of Major Depression
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Attention Deficit Hyperactivity Disorder
- Migration, Health and Trauma
- Mycobacterium research and diagnosis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- RNA modifications and cancer
- Lung Cancer Research Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Magnetic and transport properties of perovskites and related materials
Zhejiang Chinese Medical University
2023-2025
Vertex Pharmaceuticals (United States)
2024
Eli Lilly (United States)
2007-2021
Chang Gung Memorial Hospital
2006
Taipei Veterans General Hospital
2006
Abstract Background There is a burgeoning recognition that symptoms frequently coexist in ‘symptom clusters’, and comprehending these clusters may enhance the management of unrelieved patients with Crohn’s disease. However, nature dynamics symptom among newly diagnosed Chinese disease remain poorly understood. Methods A longitudinal qualitative study was adopted to explore evolution within one year. Eighteen from two tertiary hospitals southeast China were recruited through purposive...
Clinical internships are crucial in nursing education; however, they often present challenges that can elicit negative emotions among students, especially international undergraduates. Despite its importance, there is a lack of research on the experiences African undergraduates during clinical China. To explore internship undergraduate students within Chinese healthcare system. A descriptive qualitative study design was adopted. Thirteen with over three months experience China were recruited...
Background It is generally accepted that antipsychotics are more effective than placebo. However, it remains unclear whether induce a pattern or trajectory of response distinct from We used data-driven technique, called growth mixture modelling (GMM), to identify the different patterns observed in antipsychotic trials and determine drug-treated placebo-treated subjects show similar response. Method examined data on 420 patients with schizophrenia treated for 6 weeks two double-blind...
<h3>Background</h3> Rheumatoid arthritis (RA) is associated with increased neutrophil levels<sup>1</sup> and platelet<sup>2</sup> counts decreased lymphocyte levels.<sup>1,3</sup> Baricitinib (bari) a selective reversible Janus kinase (JAK)1/JAK2 inhibitor in development for patients (pts) moderate to severe RA.<sup>4</sup> <h3>Objectives</h3> To characterize changes absolute (ANC), leukocyte (ALC), platelet following once daily oral administration of bari. <h3>Methods</h3> Data were pooled...
<h3>Background</h3> Baricitinib (bari; an oral JAK 1/JAK 2 inhibitor) is in development for patients (pts) with active RA. <h3>Objectives</h3> To assess the safety of bari pts RA across 8 completed studies (4 Ph3, 3 Ph2, 1 Ph1b) and ongoing long-term extension (LTE) study. <h3>Methods</h3> Primary analysis was based on 6 4 mg QD placebo (PBO) arms dose response assessments PBO arms. In addition, all-bari set included all exposed to any dose. contained comparators. <h3>Results</h3> 3464 were...
Aims Basal insulin peglispro ( BIL ) has a longer duration of action than conventional analogues and hepato‐preferential mechanism action. This study assessed whether was non‐inferior to isophane NPH in reducing HbA1c insulin‐naïve patients with type 2 diabetes, when added pre‐study oral anti‐hyperglycaemic medications. Materials methods Phase 3, open‐label, treat‐to‐target TTT ), randomized trial 2‐week lead‐in, 26‐week treatment 4‐week safety follow‐up period. Patients were bedtime pm ,...
To longitudinally explore the symptom experience of Chinese patients with Crohn's disease within first year following their diagnosis.A longitudinal qualitative study.Eighteen newly diagnosed were recruited through purposive sampling. Semi-structured interviews conducted at four time points: soon after diagnosis, 3, 6 and 12 months post-diagnosis. Data collected between January 2021 February 2022. Conventional content analysis was used for data each point. Afterwards, point compared...
Abstract Individuals diagnosed with Crohn's disease, a chronic lifelong condition, experience dynamic or fluctuating process of developing symptom management behavior. However, less clear is how these individuals respond to and manage their symptoms over time. The aim this study was longitudinally explore the experiences disease in China. A longitudinal qualitative design used. Eighteen newly were purposely selected. Semi‐structured interviews conducted on four occasions 12‐month period....
We report on the microstructure, phase constitution and magnetocaloric properties in rapidly solidified La(Fe,Mn)11.6Si1.4 flakes prepared by strip casting technique. After a relatively short-time annealing at 1323 K for 12 h, LaFe11.6Si1.4 constituting nearly single NaZn13-structured La(Fe,Si)13, i.e. 1:13 phase, exhibit large entropy change of 19.2 J/kg adiabatic temperature 6.5 when application magnetic field 2 T which temperature. These features are comparable to those observed bulk...
<h3>Background</h3> Baricitinib (BARI) is an oral selective Janus kinase (JAK 1/2)<sup>1</sup> inhibitor approved in the EU, Japan, and other countries for treatment (tx) of moderately to severely active rheumatoid arthritis (RA) adults. RA therapies may increase risk tuberculosis (TB).<sup>2</sup> The use isoniazid (INH) plays a vital role control TB. However, INH result hepatic adverse events (AEs)<sup>3</sup>. Limited data exist on safety TB patients (pts) with treated JAK inhibitors INH....
14009 Background: Phase I of this I/II study (H3E-AA-S038) was conducted to determine the recommended dose pemetrexed (PT) when given with cisplatin (Cis) patients unresectable, advanced gastric carcinoma. Methods: Patients 18 70 years age, stage IV disease or post-surgery recurrence, no prior palliative chemotherapy, and an ECOG performance status 0 1 were included. received PT Cis on Day every 21 days. dosed at 75 mg/m 2 . dosage planned 600, 700, 800, 900 Vitamin B12 folic acid...