Abstract Despite being decked as the most prized compounds in nugget box of contrast agents for clinical radiologists, and carrying an indisputable tag safety US Food Drug Administration close to three decades, all may not be seemingly well with family gadolinium compounds. If first signs violations primum non nocere relation gadolinium-based (GBCAs) appeared millennium year published report skin fibrosis patients compromised renal function, causal relationship between development...

To prospectively investigate the role of MR spectroscopy (MRS) and diffusion-weighted magnetic resonance imaging (DWI) in assessing vertebral marrow changes postmenopausal women.Fifty women, who underwent dual-energy x-ray absorptiometry spine, were divided into three bone density groups (normal, osteopenia, osteoporosis) based on T-score. Both MRS DWI L3 body performed to calculate fat content apparent diffusion coefficient (ADC). The results compared between correlated with BMD.Vertebral...

Calcium plays an important role in the pathogenesis of ischemic cell damage. Intracellular calcium accumulation leads to neuronal damage by triggering cycle cytotoxic events. In this study, association serum levels with clinical severity stroke as defined National Institute Health Stroke Scale (NIHSS) score was evaluated.After obtaining ethical approval from institutional ethics committee, data collected 60 patients, who were divided into two groups 30 patients each: group 1 ionized less...

Background: Deviation of the nasal septum (DNS) refers to convexity one side disturbing physiology with obstructed breathing leading lateral wall abnormalities and paranasal sinuses (PNS) mucosal disease. Knowledge morphological parameters plays an important role in planning successful surgery. Our aim was evaluate angle septal deviation (ASD) on CT scan study its influence PNS disease.Methods: A prospective cross-sectional observational conducted 130 patients clinical evidence DNS chronic...

Derived from the Latin term ule, which means scarring, ulegyria is a manifestation of hypoxic ischemic encephalopathy. Recognizable on magnetic resonance imaging sequences because its characteristic features, diagnosis critical standpoint clinical management. Seizures caused by are refractory to pharmacotherapy and often do well with surgery.

To compare the Balthazar CT Severity Index and Modified in predicting outcome of acute pancreatitis. 150 cases pancreatitis, underwent CECT. The scans were reviewed scored using both indices. parameters included length hospital stay, need for intervention, occurrence organ failure, evidence infection, mortality. Descriptive statistics used baseline characteristics. Chi-square or Fisher's exact tests to two Using CTSI with patient outcome, statistically significant correlation was found...

Researchers have been digging hard to unearth the hoary past of tuberculosis. Unbelievable as it may seem, growing evidence exists that first ancestors Mycobacterium tuberculosis inhabited earth more than 2.6 million years ago. Eons before hominoids set their feet on this godly planet, and Adam Eve children came into being! Some ancient skeletal mummified fossils belonging diverse species, including dinosaurs, Pleistocene bison, other bovines like goats cows, found stamped with classic...

Background: Renal vasculature is known for having a broad spectrum of variants, and some them hold important implications at the time renal surgeries, particularly transplant. Materials Methods: This observational study was performed using multidetector computed tomography (MDCT) angiography in patients with various other abdominal disorders advised pathologies which MDCT indicated. A total 760 were evaluated. Various parameters that have surgical importance studied. Results: includes 123...

Objective: The objectives of our study were to evaluate the role conventional radiography, computed tomography (CT), and magnetic resonance imaging (MRI) in detection sacroiliitis ankylosing spondylitis (AS), along with radiological spectrum disease. Materials Methods: Thirty-six patients symptoms inflammatory back pain (IBP) evaluated CT, MRI. sacroiliac (SI) joints for joint margins, space, sclerosis, bone marrow changes. Imaging findings analyzed correlation multiple clinical...

Background: Morphometry of vertebral body (VB) and intervertebral disc space (IVD) is a reflection the osseous strength, which primarily depends on bone mineral density (BMD) host other factors. As an individual ages, internal hormonal milieu BMD undergoes change. This ubiquitous phenomenon that impacts quality life increases morbidity mortality. The pathophysiologic process causes changes in tends to alter morphology VB adjacent IVD as well. Aim: To correlate morphological lumbar VBs IVDs...

Being uncommon neoplasms of elusive origin, epithelioid hemangiomas are benign vascular tumors found in young adults.1 These mostly the head and neck region, presenting as solitary or multiple lesions, they vary between 2 3 cm diameter, morphologically manifest intradermal papules subcutaneous nodules.2 More eloquently termed angiolymphoid hyperplasia with eosinophilia on pathological basis, these amenable to surgical excision, though rare instances exist where might regress their own.3 A...

Introduction: DENV NS2B-NS3 protease inhibitors were designed based upon the reference molecule, 4-(1,3-dioxoisoindolin-2-yl)-N-(4-ethylphenyl) benzenesulfonamide, reported by our team with aim to optimize lead compound via rational approach. Top five best scoring molecules zinc ids ZINC23504872, ZINC48412318, ZINC00413269, ZINC13998032 and ZINC75249613 bearing ‘pyrimidin-4(3H)-one’ basic scaffold have been identified as a promising candidate against enzyme. Methods: The shape electrostatic...

Preeclampsia and eclampsia are hypertensive disorders of pregnancy associated with significant maternal fetal morbidity mortality. Posterior reversible encephalopathy syndrome (PRES) is a neurological complication observed in these conditions, yet its impact on fetomaternal outcomes remains underexplored. The aim this study to investigate the association between PRES women preeclampsia eclampsia.

Tuberculosis (TB) is an important health problem specially in the developing countries. Although effective chemotherapy available, compliance of patient a major challenge. The aim this study was to describe cytomorphological features drug defaulters on lymph node fine-needle aspiration cytology (FNAC) and compare it with newly diagnosed cases.A cross-sectional done for period 18 months, which all patients having tuberculous lymphadenitis were included after taking detailed history regarding...

A young female presented to us with chest complaints of 10 months duration. Imaging was done which revealed fat attenuation mass lesion in the mediastinum occupying both hemithoraces. Provisional differential diagnosis giant teratoma, mediastinal thymolipoma, large pleural lipoma or a pulmonary effusion kept. Patient underwent surgery, resected and patient discharged good condition.

Notwithstanding the unfulfilled quest for immortality, man's endeavor to outdo organ failure and prolong life has been a journey bejeweled with hues of ingenuity. This exciting odyssey marked chimerical events miracles in olden times, and, more recent, by triumphs technical cognitive advances preservation, surgical skill, immunology, management infectious diseases, multidisciplinary innovative approaches, which have collated fructify realm tissue transplantation. The remarkable...