A5009321859- Enzyme Production and Characterization
- Enzyme Catalysis and Immobilization
- Child Nutrition and Water Access
- Protein Hydrolysis and Bioactive Peptides
- Viral gastroenteritis research and epidemiology
- Birth, Development, and Health
- Complementary and Alternative Medicine Studies
- Biofuel production and bioconversion
- Preterm Birth and Chorioamnionitis
- Cervical Cancer and HPV Research
- Phytase and its Applications
- Phytochemicals and Antioxidant Activities
- Metabolism and Genetic Disorders
- Pharmaceutical and Antibiotic Environmental Impacts
- Biosimilars and Bioanalytical Methods
- Hip and Femur Fractures
- Hepatitis Viruses Studies and Epidemiology
- Animal Genetics and Reproduction
- Gestational Diabetes Research and Management
- Drug-Induced Hepatotoxicity and Protection
- Chronic Disease Management Strategies
- Trace Elements in Health
- Computational Drug Discovery Methods
- Reproductive tract infections research
- Antibiotic Use and Resistance
Government of India
2024
Ministry of Health and Family Welfare
2024
King's College London
2024
Tanzania Public health Association
2023
Dr. Yashwant Singh Parmar University of Horticulture and Forestry
2020-2022
Office of Basic Energy Sciences
2020
University of Allahabad
2012-2015
<h3>Importance</h3> Worldwide, preterm birth (PTB) is the single largest cause of deaths in perinatal and neonatal period associated with increased morbidity young children. The PTB multifactorial, development generalizable biological models may enable early detection guide therapeutic studies. <h3>Objective</h3> To investigate ability transcriptomics proteomics profiling plasma metabolomics analysis urine to identify measurements PTB. <h3>Design, Setting, Participants</h3> This...
The World Health Organization recommends 20 mg of zinc per day for 10 to 14 days children with acute diarrhea; in previous trials, this dosage decreased diarrhea but increased vomiting.
Abstract Background Bacterial pathogens cause substantial diarrhea morbidity and mortality among children living in endemic settings, yet antimicrobial treatment is only recommended for dysentery or suspected cholera. Methods AntiBiotics Children with severe Diarrhea was a 7-country, placebo-controlled, double-blind efficacy trial of azithromycin 2–23 months age watery accompanied by dehydration malnutrition. We tested fecal samples enteric utilizing quantitative polymerase chain reaction to...
The present study was designed to evaluate relative contribution of different polyphenols (total phenolics, flavonoids, flavonols) and their antioxidants activities in aqueous extracts parts some plants; Argemone mexicana , Datura metel Calotropis procera Thevetia peruviana Cannabis sativa . flavones) were determined by chemical methods. antioxidant capacities these evaluated FRAP assay. results demonstrated that phenolic content maximally leaves T. This plant exhibited minimum its flower as...
human papillomavirus (HPV) is the most common sexually transmitted virus in world. Prevalence of infection differs, with highest rates reported sub-Saharan African, including country Tanzania. In pregnancy, hormonal changes and immune seem to facilitate HPV persistence, increasing cancer risk vertical transmission towards placenta fetus. The burden still high despite multiple screening detection test available. AmpFire® assay a novel nucleic acid isothermal amplification real-time...
To augment the keratinolytic ability of Bacillus halotolerans L2EN1 isolated from poultry farm (Nahan, District Sirmour) Himachal Pradesh, different cultural conditions were optimised using One Variable at a Time (OVAT) approach accompanied by Response Surface Methodology (RSM). Optimisation results revealed that after 3rd day incubation, maximum enzyme activity was attained 45 °C, pH 11.0 with 12.5% inoculum size in presence Mn2 + and EDTA production medium. Sucrose (1.5%) yeast extract...
Efforts to map the burden of infections globally have shown a high prevalence genital infections, including Chlamydia trachomatis, in sub-Saharan Africa. This retrospective study aimed investigate selected non-viral among pregnant women Pemba Island, Tanzania. Vaginal swabs were collected during pregnancy and stored eNAT buffer. Detection C. Neisseria gonorrheae, Trichomonas vaginalis, Mycoplasma genitalium pathogens was performed by PCR using validated detection kits. samples 439 between 16...
Assessment of gestational age (GA) is key to provide optimal care during pregnancy. However, its accurate determination remains challenging in low- and middle-income countries, where access obstetric ultrasound limited. Hence, there an urgent need develop clinical approaches that allow inexpensive estimations GA. We investigated the ability urinary metabolites predict GA at time collection a diverse multi-site cohort healthy pathological pregnancies (n = 99) using broad-spectrum liquid...
Trichoderma spp. have been reported earlier for their excellent capacity of secreting extracellular α -galactosidase. This communication focuses on the optimization culture conditions optimal production enzyme and its characterization. The evaluation effects different assay parameters such as stability, pH, temperature, substrate concentrations, incubation time activity has made. most suitable buffer was found to be citrate phosphate (50 mM, pH 6.0) activity. fairly stable at higher...
To enhance the keratinolytic potential of bacterial strain Bacillus cereus N14, isolated from poultry farm Sundernagar, District Mandi, Himachal Pradesh, different process parameters like temperature, pH, incubation time, inoculum size, age etc. were optimized using One Variable at a Time (OVAT) approach and Response Surface Methodology (RSM). N14 showed maximum enzyme activity (19.5 U/mL) after 3rd day 35°C, pH 9.0, 12.5 (%) size 3 days old culture 2.5 2.0 per cent maltose yeast extract as...
Microbial α -galactosidase preparations have implications in medicine and the modification of various agricultural products as well. In this paper, four isolated fungal strains such AL-3, WF-3, WP-4 CL-4 from rhizospheric soil identified Penicillium glabrum (AL-3), Trichoderma evansii (WF-3), Lasiodiplodia theobromae (WP-4) flavus (CL-4) based on their morphology microscopic examinations, are screened for potential towards -galactosidases production. The culture conditions been optimized...
Heavy metals and pesticide residue analysis plays an important role in the quality control of medicinal plants like Vasaka (Adhatoda vasica). Hence a study was conducted to determine heavy residues this herb, which is highly useful commodity health system. The reliable, rapid nontoxic sample preparation method QuEChERS analytical methods GC-MS were proposed for simultaneous determination metal detection carried out by ICP-MS. In study, presence organophosphorus organochlorine pesticides...
A potential fungal strain of Trichoderma sp. (WF-3) was isolated and selected for the production α -galactosidase. Optimum conditions mycelial growth enzyme induction were determined. Basal media isolate containing different carbon sources like guar gum (GG), soya bean meal (SM), wheat straw (WS) combinations these substrates with basic sugars galactose sucrose used to monitor their effects on -galactosidase production. The results this study indicated that enhanced activity in (GG) (WS)....
Abstract Introduction Antimicrobial resistance (AMR) is a major public health challenge worldwide, threatening the important gains that have been made in reducing mortality due to infectious diseases. Despite current World Health Organization guidelines restricting antibiotics small subset of children with dysentery or suspected cholera, many diarrhea continue be treated antibiotics. We aim determine impact 3-day course azithromycin on risk AMR at 90 and 180 days after treatment, among their...