- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Urinary Tract Infections Management
- Gastrointestinal motility and disorders
- Inflammatory Bowel Disease
- Infant Health and Development
- Pediatric Pain Management Techniques
- Microscopic Colitis
- Gastroesophageal reflux and treatments
- Urinary Bladder and Prostate Research
- Congenital gastrointestinal and neural anomalies
- Pregnancy-related medical research
- Uterine Myomas and Treatments
- Infant Development and Preterm Care
- Helicobacter pylori-related gastroenterology studies
- Respiratory and Cough-Related Research
- Childhood Cancer Survivors' Quality of Life
- Endometriosis Research and Treatment
- Amoebic Infections and Treatments
- Gynecological conditions and treatments
- Legionella and Acanthamoeba research
- Nursing Diagnosis and Documentation
- Ectopic Pregnancy Diagnosis and Management
- Neonatal Respiratory Health Research
- Healthcare cost, quality, practices
University Medical Center Groningen
2011-2021
University of Groningen
2011-2021
Erasmus MC
2013-2015
Erasmus University Rotterdam
2013
Huisarts en Wetenschap
2010-2012
<b>Objective</b> To compare the effects of pelvic floor muscle training and watchful waiting on symptoms in a primary care population women aged 55 years over with symptomatic mild organ prolapse. <b>Design</b> Randomised controlled trial. <b>Setting</b> Dutch care. <b>Participants</b> Women or prolapse (leading edge above hymen) were identified by screening. Exclusion criteria current treatment previous year, malignancy organs, for another gynaecological disorder, severe/terminal illness,...
Objective. To (i) describe the proportion of children presenting with abdominal pain diagnosed by GP as functional (GPFAP); (ii) evaluate association between patient and disease characteristics GPFAP; (iii) diagnostic management in pain, (iv) whether GPFAP fulfill criteria for (FAP) described current literature: chronic (CAP) Rome III (PRC-III) pain-related gastrointestinal disorders (FGID). Design. Cross-sectional study. Setting. General practices Netherlands. Subjects. 305 aged 4–17 years...
Objective To compare effects and cost‐effectiveness of pelvic floor muscle training ( PFMT ) watchful waiting in women with organ prolapse. Design Randomised controlled trial. Setting Dutch general practice. Population Women (≥55 years) symptomatic mild prolapse, identified by screening. Methods Linear multilevel analysis. Main outcome measures Primary was change symptoms (Pelvic‐Floor‐Distress‐Inventory‐20 [ PFDI ‐20]) during 24 months. Secondary outcomes were condition‐specific quality...
We investigated the effectiveness and cost-effectiveness of pessary treatment compared with pelvic floor muscle training (PFMT) in women organ prolapse over a 2-year period.Randomized controlled trial (≥55 y) symptomatic prolapse, identified by screening. Participants were recruited from 20 primary care practices (October 2009-December 2012). Primary outcome was difference change symptoms (PFDI-20 score) between groups 24 months. Secondary outcomes included urinary, anorectal symptoms;...
<b>PURPOSE</b> Nonspecific abdominal pain (NSAP) is a common complaint in childhood. In specialist care, childhood NSAP considered to be complex and time-consuming problem, parents are hard reassure. Little known about family practice, but the impression that physicians consider it benign syndrome needing little more than reassurance. This discrepancy calls for better understanding of practice. <b>METHODS</b> Data were obtained from Second Dutch National Survey General Practice (2001). Using...
Dientamoeba fragilis is commonly identified in children primary care and suspected to cause gastrointestinal disease.To determine the association between D. colonization symptoms children.We performed a cross-sectional study with who presented symptoms. The associations specific were explored by means of logistic regression analyses. Asymptomatic siblings these cases invited as control subjects for case-control analysis, where we conditional analysis.In study, 107 included. Their median age...
<h3>PURPOSE</h3> Abdominal pain is a common complaint in children. Because few data exist on its natural history, we wanted to investigate the prognosis of abdominal children general practice. <h3>METHODS</h3> In prospective cohort study (aged 4 17 years) complaining pain, follow-up was at 3, 6, 9, and 12 months using standardized questionnaires. The primary outcome measure chronic pain: least 1 time month during 3 consecutive that had an impact daily activities. Prevalence, incidence,...
In specialist care, fecal calprotectin (FCal) is a commonly used noninvasive diagnostic test for ruling out inflammatory bowel disease (IBD) in children with chronic gastrointestinal symptoms. The aim of this study was to evaluate the accuracy FCal IBD symptomatic primary care.We studied 2 prospective cohorts diarrhea, recurrent abdominal pain, or both: initially seen care (primary cohort) and referred (referred cohort). (index test) measured at baseline compared 1 reference standards IBD:...
Pelvic floor symptoms are common and negatively associated with sexual function which, in turn, is an important aspect of quality life. The majority older women pelvic treated general practice but evidence from studies on the functioning these scarce.This study examined predictors inactivity those who sexually active.Cross-sectional (aged ≥55 years) 20 practices screened positive a symptom questionnaire.Logistic linear regression analyses were used to determine (PISQ-12) by assessing their...
Heavy menstrual bleeding is an important health problem. Two frequently used therapies are the levonorgestrel intra-uterine system (LNG-IUS) and endometrial ablation. The LNG-IUS can be applied easily by general practitioner, which saves costs, but has considerable failure rates. As alternative, ablation also very effective, this treatment to performed a gynaecologist. Due lack of direct comparison with ablation, there no evidence based preferred advice for use one these possibilities. A...
Heavy menstrual bleeding (HMB) is a common problem in women of reproductive age. In 2008, the Dutch guideline for general practitioners (GPs) was revised to recommend levonorgestrel intrauterine system (LNG-IUS) as first-choice treatment HMB. However, GP prescribing practices have not been studied depth.To investigate incidence and initial HMB practice, identify if there were changes after revision national 2008.Retrospective analysis data from Registration Network Groningen, Netherlands. We...
In children with suspected inflammatory bowel disease, adding calprotectin stool testing to the screening strategy has been recommended distinguish organic from nonorganic disease. this cohort study historical controls, we could not confirm that improves diagnostic yield (ratio disease-positive endoscopies and total number of endoscopies); however, in patients normal fecal levels (<50 μg/g) endoscopic histological abnormalities were seen. We propose refrain endoscopy when are normal.
Objective. To investigate the course of mental health problems in children presenting to general practice with abdominal pain and evaluate extent which characteristics during follow-up predict presence at 12 months’ follow-up. Design. A prospective cohort study one-year Setting. 53 practices Netherlands, between May 2004 March 2006. Subjects. 281 aged 4–17 years. Main outcome measures. The a depressive problem, an anxiety multiple non-specific somatic symptoms odds ratios duration,...
Abstract Background Low disease prevalence and lack of uniform reference standards in primary care induce methodological challenges for investigating the diagnostic accuracy a test. We present study design that copes with these discuss implications our choices, using quality assessment tool studies (QUADAS-2). Design The investigates value fecal calprotectin detecting inflammatory bowel children presenting chronic gastrointestinal symptoms care. It is prospective cohort including two cohorts...
<h3>PURPOSE</h3> Abdominal pain is a frequent symptom among children but rarely associated with organic disease. Although it may persist for years, no factors have been identified that predict its prognosis. Our aim was to determine whether patient characteristics at initial consultation can chronic abdominal severe enough influence the child's well-being 1 year of follow-up. <h3>METHODS</h3> We conducted this prospective cohort study in primary care, including consecutive aged 4 17 years...
In children with symptoms suggestive of inflammatory bowel disease (IBD) who present in primary care, the optimal test strategy for identifying those require specialist care is unclear. We evaluated following three strategies to determine which was referring suspected IBD care: 1) alarm alone, 2) plus c-reactive protein, and 3) fecal calprotectin.A prospective cohort study conducted, including chronic gastrointestinal referred pediatric gastroenterology. Outcome defined as confirmed by...
Faecal calprotectin is considered to be a valid test for ruling out inflammatory bowel disease (IBD) in children with chronic gastrointestinal symptoms specialist care. In contrast, faecal lactoferrin has higher specificity. The recent availability of both as point-of-care tests (POCTs) makes them attractive use primary care.To evaluate the characteristics and POCTs diagnosing IBD symptomatic children.We defined two prospective cohorts symptoms: (i) presenting care (primary cohort); (ii)...
Our aim was to design a study evaluate the effectiveness and cost-effectiveness of adding physiotherapy conventional treatment for children with functional constipation in primary care. Physiotherapy is focusing on improving coordination between pelvic floor abdominal musculature during bowel movement, while mainly symptomatic relief symptoms, therefore, we expect effects will be more sustainable than treatment. In this paper describe final how adapted, overcome recruitment problems. We...
Abstract Objective Health care expenditures for children with functional constipation (FC) are high, while conservative management is successful in only 50% of the children. The aim to evaluate whether adding physiotherapy conventional treatment (CT) a cost-effective strategy FC aged 4–18 years primary care. Methods A cost-effectiveness analysis was performed alongside randomized controlled trial (RCT) 8-month follow-up. Costs were assessed from societal perspective, effectiveness included...