A5082616490- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- Anesthesia and Pain Management
- Retinal Imaging and Analysis
- Amino Acid Enzymes and Metabolism
- Intraocular Surgery and Lenses
- Neuroscience and Neuropharmacology Research
- Advancements in Transdermal Drug Delivery
- Pelvic floor disorders treatments
- Advanced Glycation End Products research
- Adenosine and Purinergic Signaling
- Salivary Gland Tumors Diagnosis and Treatment
- Scoliosis diagnosis and treatment
- Corneal Surgery and Treatments
- Nasolacrimal Duct Obstruction Treatments
- Anesthesia and Neurotoxicity Research
- Plant-based Medicinal Research
- Nausea and vomiting management
- Glaucoma and retinal disorders
- Anesthesia and Sedative Agents
Children's Hospital of Fudan University
2019-2024
Shanghai First People's Hospital
2020
XinHua Hospital
2020
Shanghai Jiao Tong University
2020
To study the characteristics and associated factors of retinal microvascular abnormalities in children with type 1 diabetes mellitus (T1DM) without visual impairment diabetic retinopathy (DR).Case-control hospital-based including or DM. Optical coherence tomography angiography (OCTA; CIRRUS HD-OCT model 5000) was used to scan 6 × mm square area posterior retina optic disc. The indexes analyzed mainly included vascular length density (VD), perfusion (PD), foveal avascular zone area,...
To investigate the effect of OK lens treatment zone decentration on myopia control. We retrospectively selected 30 wearers who met following conditions in our hospital from more than 1300 cases: wearing both eyes and only one eye was off-center while other centric for 12 months. During period follow-up, UCVA each better 0.1 logMAR there were no obvious tropia, Kappa angle, complications such as glare diplopia. Among cases, 15 are males females, with an average age 9.3 ± 1.51Y. There...
Abstract Purpose To determine the pattern of axial variation in subjects with initial shortened length during entire period orthokeratology and to discuss possibility AL after one month becoming a predictor myopia control. Method This study retrospectively included 106 children aged 8 14 wearing OK lenses. Fifty-four eyes (AL) at first-month visit were enrolled shortening (ALS) group, fifty-two without no (NALS) group. Axial refractive error baseline within (20 months), including fitting,...
To determine the differences in myopia control efficiency and corneal reshaping between three different brands of orthokeratology (OK) lenses (Lucid, Euclid, Alpha).
Purpose: To compare the prevalence of dry eye disease between children with and without diabetes, analyze factors associated in diabetes.Materials methods: 38 diabetes were selected as cases, 40 constituted control group. The both groups was statistically analyzed. Related analyzed diabetes.Results: case group significantly higher than that (P < .01), attributable proportion among exposed (0.827) population fraction (0.700). Univariate analysis showed duration, best-corrected visual acuity,...
Abstract Purpose To study the characteristics of choroid thickness ( CT ) optic disc and macula in children with type 1 diabetes mellitus (T1 DM without visual impairment diabetic retinopathy DR analyse associated factors. Methods A square area 6 × mm around centre was scanned. The indices analysed mainly included at macular (1 mm), temporal, superior, nasal or inferior aspect inner ring (1–3 mm) outer (3–6 macula. Independent risk factors were using multifactor linear regression. Results...
To investigate the microbial profile of congenital nasolacrimal duct obstruction (CNLDO) in Chinese children.We retrospectively reviewed medical records 330 consecutive children (330 eyes) who were diagnosed with tear infections secondary to CNLDO and admitted Children's Hospital Fudan University from January 2013 2020. Bacterial cultures grown samples each patient. Samples conjunctival secretions cultivated on blood or chocolate agar. Clinically significant bacterial growth was reported.Of...
PurposeAmbulatory surgery (same-day or day surgery) is an efficient medical practice. However, there were few reports regarding the safety of ophthalmic ambulatory for children under general anesthesia. This study aims to explore its clinical complications.DesignA retrospective observational study.MethodsThe data pediatric patients who received anesthesia at Children's Hospital Fudan University from January 2015 December 2019 analyzed retrospectively. Postoperative complications, unplanned...
The purpose of this study was to evaluate the repeatability and agreement multispectral refraction topography (MRT) in measuring retinal before after cycloplegia children. results will provide valuable insights into accuracy reliability MRT as a tool for assessing pediatric patients. Children aged 7 18 years old were recruited prospective research. central peripheral measured three times using cycloplegia. deviation value (RDV) used describe average refractive error retina. In addition,...
<title>Abstract</title> Background To evaluate the repeatability and consistency of multispectral refraction topography (MRT) in measuring retinal before after cycloplegia children. Methods Children aged 7 to 18 years old were recruited this prospective research. The central peripheral measured three times using cycloplegia. deviation value (RDV) was used describe refraction. In addition, objective (OR) subjective (SR) measurements also performed. Results A total 60 children with mean age...
PurposeTo study the analgesic effects and side of a transdermal lappaconitine (TLA) patch, ibuprofen suspension (IS), TLA combined with IS (TLACIS) after adenoidectomy tonsillectomy.DesignProspective, randomized clinical trial.MethodsThe patients were into three groups defined by different drug regimens: group, TLACIS group. Pain scores at 2, 12, 24 hours surgery adverse-event reports within first postoperative week collected.ResultsUltimately, this included 102 cases in 101 At 2 surgery,...
To compare differences in central corneal thickness (CCT), curvature, and other measurements of children with diabetes mellitus (DM) healthy children, to investigate related factors. This was a case-control study. From January February 2018, 50 were selected as case group, 46 adolescents without control group. Corneal topography CCT analyzed using measuring apparatus biometrics (IOL Master). In the diabetic we whether age, course disease, sex, glycosylated hemoglobin, triglyceride level,...
The aim of this study was to research the effects glutamine synthetase (GS) and glutamate aspartate transporter (GLAST) in rat Müller cells an adenosine A2AR antagonist (SCH 442416) on GS GLAST hypoxia both vivo vitro.This used RT-PCR Western blotting quantify expressions under different hypoxic conditions as well at drug concentrations. A cell viability assay assess toxicity.mRNA protein expression Group 24 h significantly increased. mRNA increased 1 μM SCH 442416 compared with other...
Abstract Background: To compare the differences in wavefront aberrations between healthy and diabetic children with normal central vision to investigate causes of declined visual quality children.Methods: This was a case-control study. Children or without diabetes were selected as case control group. The aberration parameters, including spherical aberration, coma root mean square total higher-order corneal curvature, measured by an automatic multifunctional ophthalmoscope. Statistical...
Abstract Purpose : To determine the pattern of axial variation in subjects with initial shortened length during entire period orthokeratology and to discuss possibility AL after one month becoming a predictor myopia control. Method This study retrospectively included 106 children aged 8 14 wearing OK lenses. eyes (AL) at first-month visit were enrolled shortening (ALS) group, 52 without no (NALS) group. Axial refractive error baseline within (20 months), including fitting, washout re-wear,...