A5035798651- Food Allergy and Anaphylaxis Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Allergic Rhinitis and Sensitization
- Computational Drug Discovery Methods
- Coronary Artery Anomalies
- Electrochemical sensors and biosensors
- Asthma and respiratory diseases
- Kawasaki Disease and Coronary Complications
- Urticaria and Related Conditions
- Mesenchymal stem cell research
- Long-Term Effects of COVID-19
- Nanoparticles: synthesis and applications
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Research on Leishmaniasis Studies
- Congenital Heart Disease Studies
- Nerve injury and regeneration
- Complement system in diseases
- Cardiovascular Issues in Pregnancy
- Patient Satisfaction in Healthcare
- Saffron Plant Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Medicinal plant effects and applications
- Polyomavirus and related diseases
Golestan University of Medical Sciences
2017-2024
Creative Commons
2023
Johnson & Johnson (United States)
2023
Aja University of Medical Sciences
2016-2022
Tehran University of Medical Sciences
2008-2021
Golestan University
2021
Children's Medical Center
2016-2017
Ministry of Health and Medical Education
2016
Shahid Beheshti University of Medical Sciences
2015-2016
University of Malaya
2016
Electrochemical impedance spectroscopy (EIS) is a simple and highly sensitive technique that can be used for evaluation of the aptamer-target interaction even in label-free approach.To pursue effectiveness EIS, current study, folding properties specific aptamer methamphetamine (METH) (i.e., aptaMETH) were evaluated presence METH amphetamine (Amph). Folded unfolded aptaMETH was mounted on gold electrode surface electron charge transfer measured by EIS.The Ret methamphetamine-aptaMETH...
Widespread use of oral poliovirus vaccine has led to an ≈99.9% decrease in global incidence poliomyelitis (from ≈350,000 cases 1988 74 2015) and eradication wild-type serotypes 2 3. However, patients with primary immunodeficiency might shed vaccine-derived polioviruses (VDPVs) for extended period, which could pose a major threat polio programs. Since 1995, sixteen VDPV populations have been isolated from 14 Iran. For these patients, vaccine-associated paralysis, mostly >1 extremity, was the...
Aim: COVID-19 is a global health threat. Therapeutics are urgently needed to cure patients severely infected with COVID-19. Objective: investigate potential candidates of nsp12 inhibitors by searching for druggable cavity pockets within the viral protein and drug discovery. Methods: A virtual screening ZINC natural products on SARS-CoV-2 nsp12's was performed. lead compound highest affinity simulated dynamically 10 ns. Results: ZINC03977803 nominated as compound. The results showed stable...
Aim: Virus spike glycoprotein of SARS-CoV-2 is a good target for drug discovery. Objective: To examine the potential druggability protein pharmacophore-based discovery and to investigate binding affinity natural products with protein. Methods: Druggable cavities were searched though CavityPlus. A pharmacophore was built used hit identification. Autodock Vina evaluate hits' affinities. 10 chemical derivatives also made from backbone optimize lead compound. Results: druggable found within...
Background: Variations in the viral receptor human angiotensin-converting enzyme 2 (ACE2) may specify susceptibility of a certain population to severe acute respiratory syndrome coronavirus 2. Objective: Evaluation affinity spike glycoprotein Iranian genetic variants ACE2. Materials & methods: Single nucleotide polymorphisms ACE2 among were collected from Iranome database. Missense mutations N-terminal peptidase domain selected for silico analysis. Results: 17 missense single found at Viral...
Objective: To assess regenerative capacities of chitosan-nanoselenium conduit on transected sciatic nerve in diabetic rats.Methods: A 10-mm defect was bridged using a filled with phosphate buffered saline. In chitosan group, the saline solution. sham-operated exposed and closed. right cut ends were fixed adjacent muscle. The regenerated fibers studied within 12 weeks after surgery.Results: behavioral functional electrophysiological tests confirmed faster recovery axons group compared to...
Concerns have been expressed about the overuse of antibiotics in inpatient settings. We compared pattern antibiotic use 2010 a surgical unit university hospital Islamic Republic Iran with similar data from 2006. Defined daily doses per 100 bed-days (DBD) were calculated. Overall our increased significantly mean 4.9 (SD 5.1) DBD 2006 to 7.7 10.3) 2010. This increase was mainly due increases for treatment infections; prophylactic did not show significant increase. There an consumption...
and Longo et al [7
and Longo et al [7
Prevalence of Sensitization to Food and Inhalant Allergens in Patients with Atopic Dermatitis Gorgan, North Iran