- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Polymer crystallization and properties
- Polymer Nanocomposites and Properties
- Obsessive-Compulsive Spectrum Disorders
- Neural and Behavioral Psychology Studies
- Advanced MRI Techniques and Applications
- Mechanical Behavior of Composites
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Liquid Crystal Research Advancements
- Radio Frequency Integrated Circuit Design
- Fiber-reinforced polymer composites
- Schizophrenia research and treatment
- Acute Ischemic Stroke Management
- biodegradable polymer synthesis and properties
- Photonic and Optical Devices
- Mechanical Engineering and Vibrations Research
- Additive Manufacturing and 3D Printing Technologies
- Polymer Science and PVC
- Engineering Applied Research
- Mindfulness and Compassion Interventions
- Advancements in PLL and VCO Technologies
- Neural dynamics and brain function
- Neurological Disease Mechanisms and Treatments
- Analog and Mixed-Signal Circuit Design
Chungbuk National University Hospital
2016-2024
Chungbuk National University
2021-2024
Hyundai Motors (South Korea)
2011-2021
Weatherford College
2021
Pusan National University
1993-2017
National Medical Center
1997-2014
Hanyang University
2007-2009
Kia Motors (South Korea)
2008
National University College
2007
New Generation University College
2007
A deficit in cognitive flexibility is acknowledged as a trait for obsessive-compulsive disorder (OCD). However, no investigations to date have used activation paradigm specify the neural correlates of this OCD. The objective study was clarify how abnormal brain activities relate inflexibility OCD, using task-switching paradigm. which has two kinds task-set applied 21 patients with OCD and healthy subjects matching age, IQ sex, during an event-related functional magnetic resonance imaging...
A convergent line of neuroscientific evidence suggests that meditation alters the functional and structural plasticity distributed neural processes underlying attention emotion. The purpose this study was to examine brain differences between a well-matched sample long-term meditators controls. We employed whole-brain cortical thickness analysis based on magnetic resonance imaging, diffusion tensor imaging quantify white matter integrity in brains 46 experienced compared with matched...
Although schizophrenia is characterized by gray matter (GM) abnormalities, particularly in the prefrontal and temporal cortices, it unclear whether cerebral cortical GM abnormal individuals at ultra-high-risk (UHR) for psychosis. We addressed this issue studying thickness group with magnetic resonance imaging (MRI). measured of 29 no family history psychosis UHR, 31 patients schizophrenia, healthy matched control subjects using automated surface-based analysis structural MRI data....
Abstract Background Individuals at ultra-high risk (UHR) for psychosis have self-disturbances and deficits in social cognition functioning. Midline default network areas, including the medial prefrontal cortex posterior cingulate cortex, are implicated self-referential cognitive tasks. Thus, neural substrates within mode (DMN) potential to mediate information processing UHR subjects. Methods This study utilized functional magnetic resonance imaging (fMRI) investigate resting-state DMN...
Background Pathological gambling (PG) and obsessive-compulsive disorder (OCD) are conceptualized as a behavioral addiction, with dependency on repetitive behavior rewarding effects following compulsive behavior, respectively. However, no neuroimaging studies to date have examined reward circuitry during the anticipation phase of in PG compared OCD while considering compulsion addictive behaviors. Methods/Principal Findings To elucidate neural activities specific reward, we performed...
The blood-brain-barrier (BBB) is made up of blood vessels whose permeability enables the passage some compounds. A predictive model BBB important in early stages drug development. predicted permeabilities drugs have been confirmed using a variety vitro methods to reduce quantities candidates needed preclinical and clinical trials. Most prior studies relied on animal or cell-culture models, which do not fully recapitulate human BBB. development microfluidic models human-derived cells could...
Spatial working memory (WM) processing has 3 distinct phases: encoding, maintenance, and retrieval its dysfunction is a core feature in schizophrenia. We examined phase-specific brain activations associated with spatial WM first-degree relatives of schizophrenia (genetic high risk, GHR), ultra-high risk (UHR) subjects, patients schizophrenia, healthy controls. used an event-related functional magnetic resonance imaging 17 GHR 21 UHR 15 clinically stable 16 controls, while subjects were...
Jung WH, Kang D-H, Han JY, Jang JH, Gu B-M, Choi J-S, MH, C-H, Kwon JS. Aberrant ventral striatal responses during incentive processing in unmedicated patients with obsessive–compulsive disorder. Objective: Obsessive–compulsive disorder (OCD) is characterized by the dysfunction of control and reward mechanisms. However, only few neuroimaging studies OCD have examined processing. We neural OCD. Method: Twenty 20 age-, sex-, IQ-matched healthy controls underwent functional magnetic resonance...
Background Abnormalities in cognitive abilities such as verbal fluency and cognitive-related brain regions, particularly Broca's area, have been reported patients with schizophrenia. Additionally, previous studies demonstrated that structural functional abnormalities area were associated clinical symptoms deficits schizophrenia, suggesting this may reflect the core pathology of Thus, it is important to understand how volume connectivity changes at rest according course illness....
A CMOS millimeter-wave (mmWave) downconversion mixer with a local-oscillator (LO) buffer is proposed for wireless Gb/s data-transfer enabling systems, such as 5G systems. To obtain high linearity at low supply voltages, the mmWave adopts an on-chip transformer-based topology. In order to achieve differential single-ended conversion and IF output matching, while maintaining performance, incorporates active balun common-source common-drain configurations employing common-mode noise third-order...