A5040023454- Obsessive-Compulsive Spectrum Disorders
- Schizophrenia research and treatment
- Advanced Neuroimaging Techniques and Applications
- Pain Management and Treatment
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Mental Health and Psychiatry
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Mental Health Research Topics
- Transcranial Magnetic Stimulation Studies
- Bipolar Disorder and Treatment
- Eating Disorders and Behaviors
- Myofascial pain diagnosis and treatment
- Attention Deficit Hyperactivity Disorder
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Heart Rate Variability and Autonomic Control
- Autism Spectrum Disorder Research
- Glioma Diagnosis and Treatment
- Morphological variations and asymmetry
- Botulinum Toxin and Related Neurological Disorders
- Mindfulness and Compassion Interventions
- Face Recognition and Perception
Seoul National University Hospital
2012-2024
Seoul National University
2012-2024
Kyung Hee University
2019
New Generation University College
2008-2017
Sungkyunkwan University
2012
Samsung Medical Center
2012
University of Ulsan
2012
Asan Medical Center
2012
Ulsan College
2012
Eunpyeong Hospital
2012
Abstract Purpose To predict hematoma growth in intracerebral hemorrhage patients by combining clinical findings with non-contrast CT imaging features analyzed through deep learning. Methods Three models were developed to expansion (HE) 572 patients. We utilized multi-task learning for both segmentation and prediction of expansion: the Image-to-HE model processed slices, extracting computing a normalized DL score HE prediction. The Clinical-to-HE multivariate logistic regression on variables....
“Just Accepted” papers have undergone full peer review and been accepted for publication in Radiology: Artificial Intelligence. This article will undergo copyediting, layout, proof before it is published its final version. Please note that during production of the copyedited article, errors may be discovered which could affect content. Purpose To develop an unsupervised deep learning framework generalizable blood-brain barrier (BBB) leakage detection using dynamic contrast-enhanced (DCE)...
Objective: Reductions in the level of N -acetylaspartate within subcortical structures patients with obsessive-compulsive disorder (OCD) have been reported several studies. However, there been, as yet, no reports regarding levels prefrontal cortex adult drug-naive OCD patients. The authors used proton magnetic resonance spectroscopic imaging ( 1 H-MRSI) to investigate regional abnormalities and changes after 12 weeks pharmacotherapy citalopram Method: Thirteen 13 age- sex-matched healthy...
The Structured Interview for Prodromal Syndrome (SIPS) from Yale University is intended to diagnose prodromal syndrome of psychosis and measure the severity symptoms. Here, a Korean version SIPS presented, its reliability, validity, factor structures are examined using representative sample.The was administered 40 participants over period 1 year. inter-rater reliability internal consistency were then evaluated. In addition, structure investigated principal-axis analysis. Concurrent validity...
Given that the insula plays a contributory role in perception of chronic pain, we examined resting-state functional connectivity between insular cortex and other brain regions to investigate neural underpinnings persisting background pain patients with complex regional syndrome (CRPS). A total 25 CRPS matched healthy controls underwent magnetic resonance imaging at rest. With anterior posterior cortices as seed regions, compared strength two groups. Functional postcentral inferior frontal...
Many of previous neuroimaging studies on neuronal structures in patients with obsessive-compulsive disorder (OCD) used univariate statistical tests unimodal imaging measurements. Although the methods revealed important aberrance local morphometry OCD patients, covariance structure anatomical alterations remains unclear. Motivated by recent developments multivariate techniques field, we applied a fusion method called "mCCA+jICA" multimodal structural data T1-weighted magnetic resonance (MRI)...
The authors performed a three-dimensional shape deformation analysis to clarify the various patterns of specific thalamic nuclei abnormality using three age-matched and sex-matched groups 22 patients with obsessive-compulsive disorder (OCD), schizophrenia control participants. Compared healthy volunteers, anterior, lateral outward surface deformities thalamus were significant in OCD patients, whereas posterior, medial prominent patients. In terms asymmetry, both exhibited loss leftward...
To investigate white matter abnormalities in patients with obsessive–compulsive disorder and to clarify the relationship between discrete alterations symptom dimensions, fractional anisotropy obtained from 25 male matched normal controls were analyzed. The had a significantly lower left anterior cingulate than controls. When stratified by clinical predominant aggressive/checking dimension exhibited matter, whereas contamination/cleaning showed higher bilateral prefrontal matter. Our findings...
Impaired social functioning is one of the defining features patients with schizophrenia and subjects at ultra-high risk (UHR) for psychosis. This prospective study aimed to investigate course dysfunction in UHR examine its relationship later conversion The effect pharmacotherapy on was also examined.A total 57 58 healthy controls participated this study. Social Functioning Scale (SFS) used assess baseline 1 year follow up. changes have been examined compare those who converted psychosis...
Abstract It is widely accepted that abnormalities in the frontal area of brain underpin pathophysiology obsessive‐compulsive disorder (OCD). Fundamental to this investigation delineation white matter tracts including dorsal and ventral projections interhemispheric connections. While previous investigations OCD have examined regions, corresponding callosal connections not been investigated, despite their importance. We recruited twenty patients with (15 drug‐naïve 5 currently unmedicated)...
Background Recent studies have reported that the insular cortex is involved in pathophysiology of obsessive–compulsive disorder (OCD). However, specific morphometric abnormalities subregions remain unclear. In this study, we examined cortical volume to determine whether anterior and posterior cortices unmedicated OCD patients differed according different symptom dimensions. Methods/Principal Findings Using magnetic resonance imaging, measured gray matter volumes its (anterior divisions) 41...
Aims: To date there have been no reports of long‐term efficacy aripiprazole in Asian populations. The aim the present study was therefore to investigate efficacy, safety and tolerability a large number patients with schizophrenia, schizophreniform disorder, or schizoaffective disorder Korea. Methods: This prospective, multicenter, single‐group, 26‐week open disorder. A total 300 Korean participated study. primary measure Positive Negative Syndrome Scale (PANSS) score, secondary measures...
The aim of this study was to find peripheral biomarkers and central metabolites affecting neuroinflammation in complex regional pain syndrome (CRPS) patients using [11C]-(R)-PK11195 positron emission tomography (PET) magnetic resonance spectroscopy (MRS).Using MRS PET, we measured associations between neurometabolites 12 CRPS 11 healthy controls. Also, investigated various parameters that may affect CRPS.We found positive correlations Lipid (Lip)13a/total creatine (tCr) Lip09/tCr with...