A5035843450- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Neutrino Physics Research
- Astrophysics and Cosmic Phenomena
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Particle physics theoretical and experimental studies
- Epigenetics and DNA Methylation
- Inflammatory Biomarkers in Disease Prognosis
- RNA modifications and cancer
- Metastasis and carcinoma case studies
- Cancer-related molecular mechanisms research
- Esophageal and GI Pathology
- Dark Matter and Cosmic Phenomena
- Oral and Maxillofacial Pathology
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Sarcoma Diagnosis and Treatment
- Disaster Response and Management
- Hearing, Cochlea, Tinnitus, Genetics
- HIV/AIDS oral health manifestations
- Genetic factors in colorectal cancer
- Cancer, Lipids, and Metabolism
- Cardiac Arrest and Resuscitation
- Pleural and Pulmonary Diseases
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2025
Changzhi Medical College
2017-2025
Peking Union Medical College Hospital
2018-2025
Shanxi Medical University
2021-2024
Weatherford College
2024
Chinese People's Liberation Army
2013-2024
Anhui University
2024
Wuhan University of Science and Technology
2024
Chinese PLA General Hospital
2005-2024
First Affiliated Hospital of Xinjiang Medical University
2013-2023
There is a worldwide interest in studying SLC26A4 mutations that are responsible for enlarged vestibular aqueduct (EVA) different ethnic background and populations. The spectrum of Chinese population yet to be fully characterized. In this study, all the 21 exons were screened 107 patients with hearing loss associated EVA or both Mondini dysplasia (MD), taken from six multiplex 95 simplex families. two types control populations consisted 84 normal‐hearing subjects 46 sensorineural without...
390 Background: Combining epigenetic modulator with PD-1 inhibitor may enhance treatment outcomes in cancer patients. This study aimed to evaluate the efficacy and safety of drug decitabine, sintilimab (a inhibitor), chemotherapy gastric cancer. Methods: In this single-arm, exploratory phase II trial, patients HER2-negative, locally advanced or metastatic gastroesophageal junction (G/GEJ) adenocarcinoma were enrolled between August 12, 2021, October 22, 2022. Treatment included low-dose...
Background The emergency department (ED), usually deemed not the most frequent setting for palliative care (PC), has increasingly been mentioned its potential critical role in end-of-life patient care. However, how training affects PC performance remains to be investigated. This study aims investigate current standard of and effectiveness a Chinese medical consortium hospital. Methods We conducted an anonymous online census targeting providers questionnaire included respondents’...
Background The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), monocyte-to-lymphocyte (MLR), systemic immune-inflammatory index (SII), inflammation response (SIRI), and Onodera’s prognostic nutritional (OPNI) have been reported as markers for various cancers. We evaluated the value of NLR, PLR, MLR, SII, SIRI, OPNI poorly-to moderately-differentiated cervical squamous cell carcinoma (CSCC). Patients Methods retrospectively analyzed cases 109 patients with early-stage CSCC...
Background . To determine the ideal surgical approach (total gastrectomy (TG) vs. proximal (PG)) for Siewert type II adenocarcinoma of esophagogastric junction (AEG), we searched and analyzed Surveillance, Epidemiology, End Results (SEER) data. Methods Patients with AEG treated by TG or PG were identified from 2004–2014 SEER dataset. We obtained patients’ overall survival (OS) cancer-specific (CSS) stratified patients approach. performed a propensity score 1 : matching (PSM) analysis...
Objective COVID-19 started spreading widely in China January 2020. Outpatient fever clinics (FCs), instituted during the SARS epidemic 2003, were upgraded to serve for screening and prevention of disease transmission large tertiary hospitals China. FCs hoped relieve some healthcare burden from emergency departments (EDs). We aimed evaluate effect upgrading FC system on rates nosocomial infection ED patient attendance at Peking Union Medical College Hospital (PUMCH). Design A retrospective...
Malnutrition in cancer patients is a common but under-diagnosed condition that has negative effects on clinical outcomes. The development of an easy and reliable malnutrition assessment tool thus critical for identification nutritional support. We aimed to develop phase angle (PA)-based prediction model evaluate it patient prognosis.A retrospective cohort data consisting demographic, parameter PA test from 702 adult hospitalized between June 2020 February 2021 was analysed. PAs 6 body sites...
Prognostic indicators for gastrointestinal stromal tumors (GISTs) are under investigation. The latest risk classification criteria may still have room improvement. This study aims to investigate prognostic factors primary GISTs from three aspects, including clinicopathological parameters, immunohistochemical (IHC) expression of PTEN, and Ki-67 labeling index (LI), attempts find valuable predictors the malignancy potential GISTs. Tumor samples data 84 patients with after R0 resection were...
Abstract Soluble fibrinogen‐like protein 2 ( sFGL 2) could ameliorate acute rejection AR ) in rat cardiac transplantation. However, the role of liver transplantation has not been addressed. In this study, we found that FGL was upregulated orthotropic OLT models tolerance and positive correlation with frequency M2 Kupffer cells KC s). Gain‐of‐function experiments vitro showed promoted secretion anti‐inflammatory cytokines IL ‐10, TGF ‐β) expression CD 206, inhibited activities STAT 1 NF ‐κB...
Many clinical studies have demonstrated that the neutrophil to lymphocyte ratio (NLR), platelet (PLR), and Onodera's prognostic nutritional index (OPNI) are visibly involved in prognosis of a variety tumors. In our research, we aim determin impact NLR, PLR, OPNI for hepatocellular carcinoma (HCC).Data patients undergoing treatment Changzhi People's Hospital between 2011 2017 were reviewed. 270 with HCC under inclusion criteria. The optimal cut-off points OPNI, NLR PLR determined by using...