A5103192969- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Metabolism and Genetic Disorders
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Porphyrin Metabolism and Disorders
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Influenza Virus Research Studies
- Infectious Encephalopathies and Encephalitis
- Healthcare professionals’ stress and burnout
- Alcoholism and Thiamine Deficiency
- Respiratory viral infections research
- Inflammation biomarkers and pathways
- Immune cells in cancer
- Microbial metabolism and enzyme function
- Trauma Management and Diagnosis
- Hematological disorders and diagnostics
- COVID-19 diagnosis using AI
- Thermal Regulation in Medicine
- Image Retrieval and Classification Techniques
- Non-Invasive Vital Sign Monitoring
- Neuroinflammation and Neurodegeneration Mechanisms
- Context-Aware Activity Recognition Systems
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Peking Union Medical College Hospital
2020-2025
Jiangnan University
2018
As a hallmark of COVID-19 progression, lymphopenia alongside its subtle immune disturbance has been widely reported, but yet to be thoroughly elucidated. Aiming at exploring clinical biomarkers with accessibility in the current and acute omicron epidemic abrupted China post-control era, we design real-world prospective observation cohort Peking Union Medical College Hospital describe immunological, haematological profiles inducing lymphocyte subsets related SARS-CoV-2 infection. In this...
Importance There is limited evidence on whether higher-energy defibrillation preferred in patients experiencing out-of-hospital cardiac arrest (OHCA) with shockable rhythms. Objective To investigate the optimal energy regimen for initial and subsequent delivered by biphasic waveform automated external defibrillators (AEDs) OHCA ventricular fibrillation (VF). Design, Setting, Participants This cohort study was conducted 48 cities across China, from 2017 to 2023, among 342 who experienced at...
Objective COVID-19 started spreading widely in China January 2020. Outpatient fever clinics (FCs), instituted during the SARS epidemic 2003, were upgraded to serve for screening and prevention of disease transmission large tertiary hospitals China. FCs hoped relieve some healthcare burden from emergency departments (EDs). We aimed evaluate effect upgrading FC system on rates nosocomial infection ED patient attendance at Peking Union Medical College Hospital (PUMCH). Design A retrospective...
High-quality chest compression (CC) is the crux of survival for cardiac arrest patients. While, rescuers' position setting relative to patients during CC was unrecommended in present guidelines. We aimed assess impact settings on quality cardiopulmonary resuscitation (CPR) and test heterogeneity related characteristics.
: Sepsis-associated encephalopathy (SAE) is a common complication in the acute phase of sepsis, and patients who develop SAE have higher mortality rate, longer hospital stay, worse quality life than other sepsis patients. Although incidence as high 70% patients, no effective treatment available for this condition. To an SAE, it vital to explore its pathogenesis. It known that hyperammonemia possible factor pathogenesis hepatic ammonia potent neurotoxin. Furthermore, our previous studies...
Abstract Objectives COVID-19 began spreading widely in China January 2020. Outpatient “Fever Clinics” (FCs), instituted during the SARS epidemic 2003 were upgraded to provide screening and prevention attached large tertiary hospitals. We sought analyze effect of FCs detecting at our institution. Design A population-based cross-sectional study. Participants total 6,365 patients screened FC. Methods The FC Peking Union Medical College Hospital (PUMCH) was on 20, performed a retrospective study...
Chinese emergency department (ED) staff encountered significant mental stress while fighting the coronavirus disease 2019 (COVID-19) pandemic. We sought to investigate prevalence and associated factors for depressive symptoms among ED (including physicians, nurses, allied health, auxiliary staff). A cross-sectional national survey of who were on duty participated in combating COVID-19 pandemic was conducted March 1-15, 2020. total 6,588 medical personnel from 1,060 hospitals responded this...
Background. Hereditary coproporphyria (HCP) is a rare autosomal dominant disorder caused by partial deficiency of coproporphyrinogen III oxidase (CPOX), and systemic lupus erythematosus (SLE) an autoimmune disease with strong genetic predisposition. SLC7A7 (solute carrier family 7 member 7) may be associated monogenic disease; however, only 2 cases concomitant HCP SLE have been reported. Methods. We report 30-year-old woman six-year history presenting abdominal pain, vomiting, dysuria,...
Abstract Postoperative pulmonary complications (PPCs) are highly heterogeneous disorders with diverse risk factors frequently occurring after surgical interventions, resulting in significant financial burdens, prolonged hospitalization and elevated mortality rates. Despite the existence of multiple studies on PPCs, a comprehensive knowledge base that can effectively integrate visualize associated PPCs is currently lacking. This study aims to develop an online platform for (Postoperative...
Background In sepsis, the lung is one of worst affected organs, often leading to acute injury (ALI). More and more evidence suggests that macrophages are also involved in pathogenesis ALI. our previous study, we successfully synthesized Iron-capsaicin-based nanoparticles (Fe-CAP NPs) found it could inhibit secretion inflammatory cytokines alleviate Here, further explore anti-inflammatory mechanism Fe-CAP NPs. Methods Bone marrow-derived (BMDM) C57 mice were divided into four groups: control...
A new coronavirus pneumonia caused by 2019 (2019-nCoV) is spreading in China. Here we summarized the patients accepted fever outpatient department.Patients with epidemiologic history, respiratory symptoms or were required to go clinic for screening. Patients finally laboratory-confirmed 2019-nCoV infection real-time reverse transcription-polymerase chain reaction (RT-PCR) using nasal and pharyngeal swabs. Epidemiologic features, clinical presentation, laboratory findings image features...
Abstract Background: Reversible splenial lesion syndrome (RESLES) is a clinico-radiological characterized by the presence of reversible lesions specifically involving splenium corpus callosum (SCC). The cause RESLES unknown. However, infectious-related mild encephalitis/encephalopathy (MERS) with remains most common lesions. Acute intermittent porphyria (AIP) an autosomal dominant disorder caused partial deficiency porphobilinogen deaminase (PBGD), third enzyme in heme biosynthetic pathway....
With the rapid development of information technology, sizes digital libraries become larger and larger. How to quickly effectively search desired images in huge becomes challenge needed resolve with high priority. In this study, we firstly propose two motif-based matrices, i.e., motif average matrix (MAM) excessive (MEM), describe color texture features an image. Subsequently, terms inference MAM MEM, a (MM) is further proposed index rotated issue image retrieval. That is, light such...
Abstract Background Many patients went to the hospital presenting with acute fever, or respiratory symptoms, most of whom have a normal low leukocyte counts. The aim this study was investigate clinical characteristics and predictors pneumonia in those patients. Methods In retrospective study, adult (≥ 18 years old) fever symptoms counts (≤ 9.5 × 10 9 /L) Peking Union Medical College Hospital between 26 January 2020 March were included. Patients categorized into groups upper tract infection...