A5006981890- Mosquito-borne diseases and control
- Bioactive Natural Diterpenoids Research
- Bioactive natural compounds
- Alcohol Consumption and Health Effects
- Insect and Arachnid Ecology and Behavior
- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Phytochemistry and Bioactive Compounds
- Forest Insect Ecology and Management
- Algal biology and biofuel production
- Phytochemistry and Bioactivity Studies
- Bioactive Compounds and Antitumor Agents
- Toxoplasma gondii Research Studies
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- Heme Oxygenase-1 and Carbon Monoxide
- Viral Infections and Vectors
- Polyamine Metabolism and Applications
- Insect and Pesticide Research
- Venomous Animal Envenomation and Studies
- Eicosanoids and Hypertension Pharmacology
- Vibrio bacteria research studies
- Synthesis and biological activity
Instituto Politécnico Nacional
2016-2024
Dengue (DENV) and Chikungunya (CHIKV) viruses can be transmitted simultaneously by Aedes mosquitoes, there may co-infections in humans. However, how the adaptive immune response is modified host has yet to known entirely. In this study, we analyzed cross-reactivity neutralizing activity of IgG antibodies against DENV CHIKV sera patients from Mexican Institute Social Security Veracruz, Mexico, collected 2013 2015 using BALB/c mice inoculated with and/or CHIKV. Mice first then produced that...
Amoebiasis is produced by the parasite Entamoeba histolytica; this disease affects millions of people throughout world who may suffer from amoebic colitis or liver abscess. Metronidazole used to treat protozoan, but it causes important adverse effects that limit its use. Studies have shown riluzole has demonstrated activity against some parasites. Thus, present study aimed, for first time, demonstrate in vitro and silico anti-amoebic riluzole. In vitro, results histolytica trophozoites...
Spirulina (formerly Arthrospira) maxima (SP) is a cyanobacterium reported to have great nutritional and pharmacological potential. The objective of this study was evaluate the protective properties SP against ethanol-induced toxicity. Male Wistar rats were used in subjected 70% partial hepatectomy (PH); they then divided into five groups. During experiment, animals two groups drank an aqueous solution ethanol (EtOH) (40%, v/v). Additionally, administered extract daily at dose 200 mg/kg body...
Dengue manifestations range from a mild form, dengue fever (DF), to more severe forms such as hemorrhagic (DHF) and shock syndrome (DSS). The ability of the host present one these clinical could be related polymorphisms located in genes Toll-like receptors (TLRs) which activate pro-inflammatory response. Therefore, genotyping single nucleotide genetic (SNPs) TLR3 (rs3775291 rs6552950), TLR4 (rs2737190, rs10759932, rs4986790, rs4986791, rs11536865, rs10983755), TLR7 (rs179008 rs3853839), TLR8...
Pharmacognosy Magazine ,2019,15,65,631-637.DOI:10.4103/pm.pm_106_19Published:September 2019Type:Original Article Authors:José Angel Santiago-Cruz, Jesús Arrieta, Jazmín García-Machorro, Daniel Arrieta-Baez, and María Elena Sánchez-Mendoza Author(s) affiliations:José Santiago-Cruz1, Arrieta1, García-Machorro2, Arrieta-Baez3, Sánchez-Mendoza1 1Laboratorio De Farmacología Plantas Medicinales Mexicanas, Escuela Superior Medicina, Instituto Politécnico Nacional,Ciudad México, México 2Laboratorio...
Background Polyamines are involved in several cellular processes and inhibiting their synthesis affects chikungunya virus (CHIKV) replication translation, and, therefore, reduces the quantity of infectious viral particles produced. In this study, we evaluated inhibition CHIKV by N-ω-chloroacetyl-L-ornithine (NCAO), a competitive inhibitor ornithine decarboxylase, an enzyme which is key biosynthesis polyamines (PAs). Methods The cytotoxicity NCAO was MTT cell culture. inhibitory effect Vero...
Background and Objective: Croton reflexifolius has been used in traditional medicine for treating cancer.Although one study reported cytotoxic activity, the active compounds have not identified.Therefore, purpose of this was to isolate identify at least compound from C. through a bioassay-guided using A549 cell line.Methodology: The effect measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.Results: current indicates that leaves plant contain more than with...
Chikungunya virus (CHIKV) is classified as a pathogen with the potential to cause pandemic. This situation becomes more alarming since no approved drug exists combat virus. The present research aims demonstrate anti-CHIKV activity of molecules in latex Euphorbia grandicornis. Therefore, biodirected assay was carried out find activity. Extractions hexane, dichloromethane, and methanol subsequent purification by column chromatography were later evaluate cytotoxic...