A5066619762- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Genital Health and Disease
- Endometrial and Cervical Cancer Treatments
- Antimicrobial Resistance in Staphylococcus
- Endometriosis Research and Treatment
- Neonatal and Maternal Infections
- Reproductive tract infections research
- Streptococcal Infections and Treatments
- Asthma and respiratory diseases
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Cancer survivorship and care
- Patient-Provider Communication in Healthcare
- Uterine Myomas and Treatments
- Urological Disorders and Treatments
- Colorectal and Anal Carcinomas
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Immunotherapy and Immune Responses
- Hepatitis B Virus Studies
Aarhus University Hospital
2014-2025
Regional Hospital Randers
2020-2025
Aarhus University
2020-2024
Skive Hospital
2018
Regionshospitalet Viborg
2017
Abstract Background State Trait Anxiety Inventory (STAI) scale was developed in the 1980’s and has been widely used both clinical settings research. However Danish version of STAI not validated. The aim this study to assess validity reliability - state anxiety women aged 45 years older with abnormal cervical cancer screening results. Methods Women ≥45 referred an cytology healthy volunteers ( n = 12) underwent cognitive interview after completing STAI. Further, sent out electronic...
To compare the proportion of cervical intraepithelial neoplasia grade 2 or higher (CIN2+) in biopsies with that large loop excision transformation zone (LLETZ) specimens women aged ≥45 years type 3 (TZ3).
To evaluate the clinical utility of p16/Ki67 dual-stain (DS) compared with cytology for detecting cervical intraepithelial lesion grade two or worse (CIN2+) in women a transformation zone type 3 (TZ3).Cross-sectional study.Colposcopy clinics Central Denmark Region.Women aged 45 years older referred colposcopy because an abnormal screening test.All had sample collected and DS testing underwent large-loop excision (LLETZ).Sensitivity, specificity negative (NPV) positive (PPV) predictive values...
Abstract Introduction Diagnostic work‐up of older women with a positive cervical cancer screening test is often challenging due to incomplete visualization the transformation zone. To reduce risk missing disease, diagnostic excision may be performed. However, little known on treatment efficacy and post‐treatment surveillance for women. We aimed investigate proportion testing negative human papillomavirus (HPV) following an abnormal test. Material Methods conducted prospective cohort study...
Cervical cancer incidence and mortality have declined dramatically after screening for cervical was implemented. Yet, studies reported high rates at older age despite low HPV prevalence of precursor lesions. The underlying reason these findings remains unclear. However, it is well known that the impact depends not only on uptake effectiveness but also diagnostic workup (ie colposcopy), treatment follow-up. In women, sensitivity performance colposcopy are impaired due to age-dependent changes...
Abstract Background Immunocytochemical staining with p16/Ki67 has been suggested as a promising triage biomarker in cervical cancer screening. As dual is subjective method, proper training may be required to ensure safe implementation routine laboratories and reduce risk of misclassification. We determined concordance between novice evaluators an expert, stratified by number slides reviewed at three reading points. Methods The study was conducted the Department Pathology, Randers, Denmark....
Abstract Background Cervical cancer incidence and mortality rates are high in older women many developed countries, including Denmark. Therefore, Danish aged 69 were invited for one additional human papilloma virus (HPV) based screening test 2017. Here, we describe the clinical management detection rate of cervical intraepithelial neoplasia grade 2 or worse (CIN2 +) screen-positive referred colposcopy. Methods We conducted an observational study public gynecology departments Central Denmark...
The incidence of cervical cancer peaks around the age 75 years, and elderly patients are more frequently diagnosed with advanced-stage than younger patients. There is considerable practice variation regarding follow-up abnormal test results at risk cancer, both nationally internationally, due to uncertainty about risks benefits for this particular patient group. treatment preferences these are, however, poorly described in current literature. aim study was explore patients' experiences...
Corpus uteri cancer is the most common gynecological malignancy in developed countries. The disease typically diagnosed at an early stage, of endometrioid histologic subtype, and has a fairly good prognosis. Here, we describe hysterectomy-corrected mortality rates corpus cancer, overall stratified by age, stage subtype. Using data from nationwide Danish registries, calculated uncorrected age-standardized among women ≥35 years during 2002 to 2015. Individual-level hysterectomy status was...
A woman diagnosed with a recurrent vulval carcinoma after initial treatment radiochemotherapy is presented. After three additional relapses she was vaccinated Gardasil. She has had no in her vulvar area for 39 months and an overall progression-free survival of almost 24 months.
To measure anxiety levels in women aged ≥45 years undergoing diagnostic large loop excision of the transformation zone (LLETZ) at first colposcopy visit.Longitudinal study.Three clinics Central Denmark Region.Women LLETZ.Women completed State-Trait Anxiety Inventory (STAI) and Short Form 12 (mental physical health) questionnaires before, immediately after, 1 6 months after LLETZ.STAI state median scores were calculated stratified by health status, letter with information about screening...
Introduction Colposcopy is a standard procedure for evaluating cervical abnormalities and collecting biopsies. The associated with intra- inter-observer variation. A colposcopic scoring system, Swedescore, has been designed to standardise facilitate colposcopy training. Swedescore performed well in routine clinical setting when used by expert colposcopists find or exclude high-grade lesions. Danish guidelines differ from other countries, as they recommend four biopsies all women regardless...
Cancer of the urethra is very rare with an age-adjusted incidence only 0.6 per million women in Europe. The etiology multifactorial and increases age, highest rates patients 75 years or older. We herein describe a 58-year-old woman referred to our unit due pollakisuria repeated lower urinary tract infections. gynecological examination revealed suspect area anterior wall vagina. Subsequently, ultrasound examination, MRI, PET-CT scan followed by vaginal biopsies urethral adenocarcinoma.