A5102816360- Neurological Disease Mechanisms and Treatments
- Healthcare and Venom Research
- Mathematical Biology Tumor Growth
- Glioma Diagnosis and Treatment
- Animal Genetics and Reproduction
- Cardiovascular Function and Risk Factors
- Corneal Surgery and Treatments
- Bone and Joint Diseases
- Organ and Tissue Transplantation Research
- Hedgehog Signaling Pathway Studies
- Cardiovascular Disease and Adiposity
- Reproductive System and Pregnancy
- Neurological Disorders and Treatments
- Cell Adhesion Molecules Research
- Genetics and Neurodevelopmental Disorders
- Genomics and Rare Diseases
- RNA regulation and disease
- MRI in cancer diagnosis
- Nerve Injury and Rehabilitation
- Autoimmune Neurological Disorders and Treatments
- Nitric Oxide and Endothelin Effects
- COVID-19 Impact on Reproduction
- Diabetes Management and Education
- Glutathione Transferases and Polymorphisms
- Pressure Ulcer Prevention and Management
Qiqihar Medical University
2021-2022
University of Hong Kong
2021
Fujian Provincial Hospital
2008-2019
Fujian Medical University
2019
Wuhan University
2017
South Central Minzu University
2017
Fourth Affiliated Hospital of Guangxi Medical University
2013
First Affiliated Hospital of GuangXi Medical University
2012
Guangxi Medical University
2012
Nanjing Tech University
2012
Dermatological problems in diabetes might play an important role the spontaneous ulcers and impaired wound healing that are seen diabetic patients. Investigation of cause skin disorders is critical for identifying effective treatment. The abdominal full-thickness tissues 33 patients (14 nondiabetic 19 diabetic) were analyzed. cell viability malondialdehyde (MDA) production fibroblasts measured after advanced glycosylation end product (AGE)-bovine serum albumin (BSA) exposure. Cutaneous...
Purpose To determine longitudinal relationships between lumbar vertebral bone marrow permeability and adipose tissue in a rabbit diabetes model by using quantitative dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging iterative decomposition of water fat with the echo asymmetry least-squares estimation quantitation (IDEAL IQ) sequence. Materials Methods Twenty rabbits were randomly assigned to diabetic (n = 10) or control group. All underwent sagittal MR region at fixed...
This study aimed at exploring the expression level of LTBP1 in mouse model epilepsy. The mechanism epileptic cerebral neural stem cells was deeply investigated to control occurrence epilepsy with neuroprotection.
This study aimed to explore the expression level of miR-539 in blood-brain barrier permeability induced by cerebrovascular occlusion and its mediated mechanism. Altogether, 48 patients with cerebral vascular lesions from March 2018 June 2020 were collected. The peripheral blood serum subjects was analyzed qRT-PCR, participants divided into two groups according results head neck ultrasound CTA hemodynamics. MCAO model ischemia established rats, detected qRT-PCR brain tissues different rats....
Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic methods often lack generalizability when applied to unseen datasets. Recently, the success of foundation models (FMs) has provided more generalizable solution, potentially enabling any cell type. In this study, we perform large-scale evaluation three widely used state-of-the-art (SOTA) (Cellpose, StarDist, and CellViT). Specifically, created highly diverse dataset consisting 2,542 whole...
Training AI foundation models has emerged as a promising large-scale learning approach for addressing real-world healthcare challenges, including digital pathology. While many of these have been developed tasks like disease diagnosis and tissue quantification using extensive diverse training datasets, their readiness deployment on some arguably simplest tasks, such nuclei segmentation within single organ (e.g., the kidney), remains uncertain. This paper seeks to answer this key question,...
To compare the efficacy and safety of complete transperitoneal laparoscopic nephroureterectomy (CTNU) traditional retroperitoneoscopic nehroureterectomy (TRNU) for management upper urinary tract urothelial carcinoma(UTUC).We retrospectively collected clinical data UTUC patients who underwent CTNU or TRNU surgery from January 2011 to December 2018 in Peking University First Hospital Fujian Provincial Hospital, compared characteristics, perioperative parameters, follow-up results between...
Objective: To investigate the clinical features and genetic characteristics of patients with TBC1D24 gene mutation related early-onset focal myoclonic epilepsy. Methods: Clinical data 3 epilepsy Xuanwu Hospital from November 2016 to June 2017 was collected analyzed.Candidate mutations were screened by second generation sequencing. Results: Among patients, 1 male 2 females.Seizure onset age 4 months, years 5 after birth respectively. Two had family history epilepsy.They all prolonged episodes...
Objective To explore the effects of nursing on hospitalized patients with diabetic.Methods A total 120 diabetes mellitus who were treated in our hospital from October 2011 to 2012 April randomly divided into observation group and control group,60 cases each group.The traditional methods used group,The targeted measures based scores anxiety depression life quality,compliance compared between two groups.Results The score was 28.19 ± 3.36,the 32.27 6.62 group,the 36.47 2.97,the 38.92-± 5.58...
ISEE-550 Objective: Our aim was to assess whether the functional Val16Ala polymorphism in manganese superoxide dismutase (MnSOD) gene is associated with risk of oral squamous cell carcinoma (OSCC). Materials and Methods: Participants OSCC or precancerous lesions (OPL) were recruited from Kaohsiung Medical University hospital physician diagnosis histological confirmation. Healthy controls randomly selected a community survey for cancer. The MnSOD genotypes determined using PCR–RFLP technique....
Objective To report a method and clinical effect of endoscope assisted surgery for treatment lower trunk type thoracic outlet syndrome.Methods fourteen cases plexus syncLrome were treated with transaxillary first nb reaction by endoscope.Results All the eases followed 12 to 24 months postoperatively.Symptoms relieved in all 14 there was no one recurrence.For 4 muscle atrophy dorsal interosscous muscle,complete restoration achieved 2 partial cases.According Wood's evaluation criteria,the...
Objective To explore the role of changes in endogenous L-citrulline levels and arginases expression erectile dysfunction diabetic rats, investigate effect incubation ex vivo on dysfunction. Methods Type 2 rats were induced by high fat diet plus a single intraperitoneal injection small dose streptozotocin (30 mg/kg), followed for 8 weeks. The function was reflected relaxation response to acetylcholine (ACh) corpus cavernosum detected isometric tension measurement. Levels nitric oxide...
Diabetic cardiomyopathy is a major cause of morbidity and mortality among diabetic patients. Endoplasmic reticulum (ER) stress has been involved in cardiomyopathy. Accumulation endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA) associated with cardiovascular complications. This study was to determine whether ADMA accumulation contributes its mechanism related ER streptozotocin-induced rats cultured rat cardiomyocytes. Cardiac function measured by...
Diabetic patients show a high sensitivity to myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism has remained obscure. Increasing evidence indicates that protein arginine methyltransferase1 (PRMT1) is implicated in modulation of cellular processes including gene transcription, energy metabolism, apoptosis and generation asymmetric dimethylarginine (ADMA), an endogenous inhibitor nitric oxide synthase (NOS). ADMA as intermediate methylation catalyzed by PRMT1 associated...