A5046724501- Vector-borne infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- IgG4-Related and Inflammatory Diseases
- Insect-Plant Interactions and Control
- Study of Mite Species
- Vector-Borne Animal Diseases
- Insect symbiosis and bacterial influences
- Gastrointestinal disorders and treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Meningioma and schwannoma management
- Zoonotic diseases and public health
- Cancer Genomics and Diagnostics
- Insect and Pesticide Research
- Glioma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Neuroendocrine Tumor Research Advances
- Vasculitis and related conditions
- Inflammatory Biomarkers in Disease Prognosis
- Spinal Dysraphism and Malformations
- Congenital Ear and Nasal Anomalies
- Myasthenia Gravis and Thymoma
- Public Health and Social Inequalities
Cornell University
2024-2025
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2018-2024
Weill Cornell Medicine
2024
University of Tübingen
2024
Mayo Clinic in Arizona
2023
Universidad Nacional Autónoma de México
2018-2020
Universidad de Sonora
2014-2019
Universidad Veracruzana
2019
National Institute of Genomic Medicine
2019
University of California, Davis
2019
The goal of this study was to reassess the taxonomic status A. maculatum, triste and tigrinum by phylogenetic analysis five molecular markers [four mitochondrial: 12S rDNA, 16S control region (DL) cytochrome c oxidase 1 (cox1), one nuclear: ribosomal intergenic transcribed spacer 2 (ITS2)]. In addition, phenotypic diversity adult ticks identified as maculatum from geographically distinct populations thoroughly re-examined.Microscopic examination four putative morphotypes distinguishable...
Several reports describing a rare primary liver tumor with histologic features reminiscent of follicular thyroid neoplasms have been published under variety descriptive terms including thyroid-like, solid tubulocystic, and cholangioblastic cholangiocarcinoma. Although these tumors are considered to represent variants, they lack classic cholangiocarcinoma unique characteristics, namely immunoreactivity for inhibin NIPBL::NACC1 fusions. The purpose this study is present clinicopathologic...
The Rhipicephalus sanguineus group encompasses at least 12 validated species of Palearctic and Afrotropical hard ticks, which are relevant in veterinary medicine public health. taxonomy R. s.s., has been particularly intensely debated, due to its wide geographic distribution, morphological variants, parasite-host associations, capacity vectorial competence for the transmission several pathogens. By sequencing mitochondrial markers, it was possible identify existence multiple lineages, among...
During a study to identify zoonotic pathogens in northwestern Mexico, we detected the presence of rickettsial agent Dermacentor parumapertus ticks from black-tailed jackrabbits (Lepus californicus). Comparison 4 gene sequences (gltA, htrA, ompA, and ompB) this showed 99%-100% identity with Rickettsia parkeri.
Rickettsia parkeri is an emerging human pathogen transmitted by Amblyomma ticks in predominately tropical and subtropical regions of the western hemisphere. In 2014 2015, one confirmed case probable R. rickettsiosis were reported from Pajarita Wilderness Area, a semi-arid mountainous region southern Arizona. To examine more closely potential public health risk this region, study was initiated to investigate pervasiveness maculatum Koch group areas Arizona ascertain infection frequencies...
Abstract Background Rocky Mountain spotted fever (RMSF) is a significant public health problem in Sonora, Mexico, resulting thousands of cases and hundreds deaths. Outbreaks RMSF are perpetuated by heavy brown dog tick infestations around homes. During 2009–2015, there were 61 23 deaths single community Sonora (Community A). Methods An integrated intervention was carried out from March–November 2016 aimed at reducing populations with long-acting acaricidal collars on dogs, environmental...
We present a series of four pregnant women with Rocky Mountain spotted fever (RMSF) that occurred in Sonora, Mexico, during 2015-2016. Confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens Rickettsia rickettsii using an indirect immunofluorescence antibody assay. Each patient presented and petechial rash was treated successfully doxycycline. the one full-term infant delivered at 36 weeks gestation survived infection. Three patients their first...
We found Rickettsia parkeri in Amblyomma ovale ticks collected Veracruz, Mexico, 2018. sequenced gene segments of gltA, htrA, sca0, and sca5; phylogenetic reconstruction revealed near-complete identity with R. strain Atlantic Rainforest. Enhanced surveillance is needed Mexico to determine the public health relevance this bacterium.
Rocky Mountain spotted fever is a highly lethal infectious disease, particularly if specific treatment with doxycycline given belatedly.To describe the clinical profile of fatal cases in hospitalized patients state Sonora, México.We conducted cross-sectional study on series 47 deaths caused by Rickettsia rickettsii from 2013 to 2016. The diagnosis was confirmed single blood sample polymerase chain reaction (PCR) or four-fold increase immunoglobulin G measured paired samples analyzed indirect...
Characterize clinical manifestations and predictors of mortality in children hospitalized for spotted fever.Cross-sectional study 210 subjects with a diagnosis Rocky Mountain fever (RMSF) pediatric hospital Sonora, from January 1st, 2004 to June 30th, 2015. Data were analyzed using descriptive statistics multivariate logistic regression.An upward trend was observed RMSF morbidity mortality. Fatality rate 30%.Three associated risk death: delay ≥ 5 days at the start doxycycline (ORa= 2.95, 95%...
Rocky mountain spotted fever is a public health problem in America. The disease remains as challenge for Health Systems at regional level. It an illness of medical relevance due to its high case-fatality rate when it not diagnosed and treated early. Although anyone susceptible infection, some groups are more vulnerable increased exposure ticks, including children who have higher morbidity fatal outcomes. A myriad biological, ecological social factors, complexly interrelated, associated with...
Abstract Amblyomma maculatum Koch sensu lato (s.l.) ticks are the vector of Rickettsia parkeri in Arizona, where nine cases R. rickettsiosis have been identified since initial case 2014. The current study sought to better define geographic ranges and pathogen assess potential public health risk posed by this region southwestern United States. A total 275 A. s.l. were collected from 34 locations four counties Arizona one county New Mexico screened for DNA species. was detected 20.4% ticks,...
Background/Objective The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria (2019 AECC) for IgG4-related disease (IgG4-RD) is considered a significant advancement in the study this condition. Most studies evaluating their performance have focused on White and Asian patients, leaving knowledge gap regarding Latin populations. Therefore, aimed to assess AECC IgG4-RD cohort patients. Methods A multicenter medical records review was conducted,...
Thrombotic events are well documented in primary erythrocytosis, but it is uncertain if secondary etiologies increase the risk of thrombosis. This study aimed to determine causes erythrocytosis and identify its impact as a factor for thrombosis.Data were obtained from patients with between 2000 2017 at referral hospital Mexico City. Erythrocytosis was defined according 2016 WHO classification. Time thrombosis, major bleeding, or death compared among groups by etiology using Cox regression...
The genus Pseudoplatystoma includes catfish species distributed throughout the fresh waters of South America. These are important fisheries resources and play a significant ecological role due to their piscivorous migratory habits. taxonomy this is still debated: traditionally, only three have been recognised, but recently, number was raised eight. validity these eight morphospecies, however, not confirmed by two subsequent molecular phylogenetic studies, which identified either five or four...