A5062283041- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Parasites and Host Interactions
- Amoebic Infections and Treatments
- Toxin Mechanisms and Immunotoxins
- Insect and Pesticide Research
- Child Nutrition and Feeding Issues
- Cytomegalovirus and herpesvirus research
- Insect Pest Control Strategies
- Pneumocystis jirovecii pneumonia detection and treatment
- Parasitic infections in humans and animals
- Circadian rhythm and melatonin
- Helminth infection and control
- Attention Deficit Hyperactivity Disorder
- Parasite Biology and Host Interactions
- Heme Oxygenase-1 and Carbon Monoxide
- Health and Well-being Studies
- Fungal Infections and Studies
- Insect symbiosis and bacterial influences
- Travel-related health issues
- Circular RNAs in diseases
- Herpesvirus Infections and Treatments
- Syphilis Diagnosis and Treatment
Iran University of Medical Sciences
2013-2024
Tehran University of Medical Sciences
2006-2013
Tarbiat Modares University
2004
Recent circumstantial evidence suggests that an increasing number of Iranian patients with cutaneous leishmaniasis are unresponsive to meglumine antimoniate (Glucantime), the first line treatment in Iran. This study was designed determine whether clinical responses (healing, or non-healing) were correlated susceptibility Leishmania parasites Glucantime.In vitro testing performed on 185 isolated intracellular mouse peritoneal macrophage model. A strong correlation between outcome and...
Oropharyngeal candidiasis is the commonest mucocutaneous infection in HIV‐positive individuals. Herein, samples were taken from oral cavities of 150 HIV‐infected patients and cultured on Sabouraud‐dextrose agar; 89 (59·3%) had positive culture for Candida presented clinical sign classical candidiasis. Totally, 102 morphologically distinct colonies isolated cultures subsequently identified by polymerase chain reaction sequencing assay, presenting following frequency: 54 C. albicans (52·9%),...
The aim of this study was to determine the prevalence all parasitic forms (eggs, larvae, cysts and oocyst) by using two flotation methods in soil public places children’s playgrounds Tehran City, Capital Iran. During 2008 2009, 150 samples were collected from various sites simple random selection. To recover parasites, examined sodium nitrate flotation, sucrose method. McNemar test Kappa Index used analyse statistical significance results. parasites as follows:Toxocara spp. eggs (38.7%)...
The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance increasing in endemic regions such as Iran. Understanding molecular basis to antimonials could be helpful improve treatment strategies. This study aimed recognize genes involved Leishmania tropica field isolates. Sensitive and resistant L. parasites were isolated from anthroponotic cutaneous patients drug susceptibility meglumine antimoniate (Glucantime®) was confirmed...
Neglected tropical diseases (NTDs) like zoonotic cutaneous leishmaniasis (ZCL), is a widespread infectious disease with high mortality and morbidity. Various medications are used for treating the disease, but several side effects drug resistance have been reported. Herbal medicines unlimited sources discovering new to treat diseases. We aimed determine leishmanicidal activity of three species Iranian Artemisia herbal plant extracts in in-vitro.In-vitro anti-leishmanial ethanolic on both...
In order to define the protein expressional changes related process of meglumine antimoniate resistance in anthroponotic cutaneous leishmaniasis (CL), we performed a comparative proteomics analysis on sensitive and resistant strains Leishmania tropica isolated from Iranian CL patients.Cell proteins were analysed with 2-dimensional electrophoresis differentially expressed identified by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry.Image matched maps 7 that...
Photodynamic therapy (PDT) is alternative treatment of cutaneous leishmaniasis (CL), and phenolthiazine dyes such as Toluidine Blue O (TBO) have the potential role in PDT notably affect parasites inactivation. This study aimed to evaluate effectiveness by using TBO a light-emitting diode (LED) zoonotic CL (ZCL).The was conducted Iran University Medical Sciences, Tehran, 2018-2020. Different concentration (7.8 μg/mL up 500 μg/mL) photosensitizer 630 nm LED light source were used for...
As the cause of RBC infection and splenomegaly, malaria remains a major parasitic disease in world. New specific biomarkers such as MicroRNAs (miRNAs) are developed to accurately diagnose clarify its pathologic changes. This study aimed at evaluating changes plasma miRNAs markers Plasmodium vivax patients with Chabahar, Iran.For present descriptive-analytical conducted 2018, we collected blood samples from 20 individuals. Real-time quantitative Polymerase Chain Reaction (RT-qPCR) was used...
Clinical features and severity of the leishmaniasis is extremely intricate depend on several factors, especially sand fly-derived products. Bacteria in fly’s gut are a perpetual companion Leishmania parasites. However, consequences concomitance these bacteria parasite outside midgut environment have not been investigated infection process. Herein, needle model was designed to mimic transmission by flies, examine differences onset progression L. major initiated inoculation with “low” or...