- China's Ethnic Minorities and Relations
- Adipose Tissue and Metabolism
- Hong Kong and Taiwan Politics
- Neurological Disorders and Treatments
- Stroke Rehabilitation and Recovery
- Sleep and related disorders
- Acute Ischemic Stroke Management
- Neurotransmitter Receptor Influence on Behavior
- Tryptophan and brain disorders
- Peroxisome Proliferator-Activated Receptors
- Biochemical effects in animals
- Regional Development and Management Studies
- Robotic Mechanisms and Dynamics
- Local Government Finance and Decentralization
- Advanced Glycation End Products research
- Neonatal and fetal brain pathology
- Pain Mechanisms and Treatments
- Climate Change and Sustainable Development
- MicroRNA in disease regulation
- Sirtuins and Resveratrol in Medicine
- Microplastics and Plastic Pollution
- Immunodeficiency and Autoimmune Disorders
- Connexins and lens biology
- Historical Geopolitical and Social Dynamics
- Globalization, Economics, and Policies
Jiangsu University
2016-2024
Yixing People's Hospital
2016-2024
Wenzhou Medical University
2017-2019
First Affiliated Hospital of Wenzhou Medical University
2017-2019
Xiamen University
2002-2009
Shanghai Jiao Tong University
2007-2008
Shanghai University
2006
Suzhou University of Science and Technology
2005
Post-stroke cognitive impairment (PSCI) is an increasingly prevalent sequel after stroke that may associate with poor functional outcome and increased risk of recurrent stroke. We aimed to explore the relationship between oxidative stress biomarkers presence PSCI. 193 first-ever acute ischaemic patients were consecutively enrolled in current study. The malondialdehyde (MDA) 8-hydroxydeoxyquanosine (8-OHdG) measured within 24 h admission. Cognition function was evaluated by Mini-Mental State...
Purpose: Post-stroke depression (PSD) is a psychiatric complication after stroke that leads to poorer outcomes. Recent observational studies have indicated lipid profiles were associated with higher risk of and depression. This study aims further explore the possible relationship between serum development PSD. Methods: A total 373 acute ischemic patients examined. Serum including high-density lipoprotein cholesterol (HDL-C), low-density (LDL-C), triglycerides (TG), (TC), apolipoprotein A1...
In this study, methionine sulfoxide (MetO) was identified as an active metabolite that suppresses adipogenesis after screening obese individuals versus the normal population. MetO suppressed gene and protein expression of CCAAT/enhancer binding (C/EBP) α, adipocyte fatty acid 4 (FABP4), nuclear receptor peroxisome proliferator-activated γ (PPARγ) during human preadipocyte (HPA) differentiation. Adipogenesis decreased following treatment; however, number, proliferation, apoptosis were...
The purpose of this work is to investigate the function SNHG1, a long non-coding RNA implicated in disease progression, apoptosis, and proliferation, order solve problem hypoxic-ischemic encephalopathy (HIE) newborn care. We investigated impact overexpressing SNHG1 on hypoxia-induced apoptosis studied its expression BV2 microglial cells under hypoxic circumstances. As result modifying YY1 expression, SNHG1′s overexpression prevents as our data demonstrate that it considerably downregulated...
Background: Post-stroke depression (PSD) is a disease with high incidence in stroke patients. It reported that about one third of patients may develop after stroke. Elevated levels plasma fibrinogen are found Our study aims to find out whether there relationship between level and PSD. Methods Findings: 406 acute ischemic were admitted our study. Plasma assayed at hospital admission measured by the method Clauss Stago auto analyer STA kit (Diagnostic Stago, Taverny, France). Clinical was...
Introduction: Mitochondria are essential for generating cellular energy and significant in the pathogenesis of obesity. Peptide PDBSN has been demonstrated to inhibit adipogenic differentiation adipocytes vitro improves metabolic homoeostasis vivo. Therefore, this study, we further investigated effects on morphology, synthesis, function adipocyte mitochondria. Methods: Human visceral subcutaneous primary preadipocytes (HPA-v HPA-s) were cultured into mature adipocytes. Intracellular...