Background: Secondary lymphedema is often observed in postmalignancy treatment of the breast and gynecologic organs, but effective therapies have not been established chronic cases even with advanced physiologic operations. Currently, reconstructive surgery novel approaches has attempted. Methods: The hindlimbs 10-week-old male C57BL/6J mice, after 30-Gy x-irradiation, surgical lymph node dissection, 5-mm gap creation, were divided into four groups, vascularized transfer abdominal flap 1.0 ×...

Secondary lymphedema is observed in common after postmalignancy treatment of the breast and gynecologic organs but effective therapies are not established. Adipose-derived stem cells (ADSCs), which pluripotent, regenerative local injection, tested for murine hindlimb secondary by method.Mice were divided into four groups: no ADSCs, 1 × 10(6) 10(5) ADSCs 10(4) (each group, n = 20) a stringent surgical resection irradiation. Circumferential measurement, lymphatic flow assessment quantification...

Delayed wound healing in lymphedema is assumed to be caused by two reasons, pathophysiological and immunological effects of lymphedema. The aim this review establish how impaired lymphatics alter pathophysiologically immunologically, propose treatment modalities that can promote Lymphaticovenular anastomoses (lymphovenous [LVAs]) were performed on patients who had recurrent cellulitis several times with lymphorrhea developed severe ulcers refractory skin grafts, flaps, conservative therapy....

Background: Treatment of critical limb ischemia is sometimes difficult because the patient’s condition, and some novel approaches are needed. Methods: The hindlimbs Sprague-Dawley rats, after 20-Gy x-ray irradiation surgical occlusion, were divided into four groups: with a superficial fascial flap, 5.0 × 10 6 adipose-derived stromal/stem cells, both combined. rats tested for laser tissue blood flow, immunohistologic vessel density, foot paw punch hole wound healing. Green fluorescent...

Although patients with obesity-induced lymphedema can be treated by weight loss therapy, they find it difficult to lose the required amount of weight. The aims this study were clarify characteristics lymphatic vessels in and determine feasibility efficacy lymphovenous anastomosis (LVA) these patients.Twenty-two (44 edematous lower limbs) a body mass index (BMI) >35 kg/m2 (obese group) 91 (141 BMI <25 enrolled as control group (nonobese underwent LVA. diameter depth lymphatics effect LVA...

Lymphoscintigraphy and indocyanine green (ICG) lymphography reveal the severity of extremity lymphedema. Lower lymphedema (LEL) index NECST classification are related to clinical We aimed investigate correlation between lymphatic surgery, imaging, in patients with Thirty-five lower-extremity who underwent venous anastomosis (LVA) were evaluated. Ten thirty-five multi-surgery (additional vascularized transfer and/or liposuction). investigated LEL index, classification, lymphoscintigraphy...

Liposuction is the most frequently performed debulking procedure in patients with lymphedema. However, it remains uncertain whether liposuction equally effective for upper extremity lymphedema (UEL) and lower (LEL). In this study, we retrospectively compared effectiveness of according to was LEL or UEL, identified factors associated outcomes.All had been treated at least once by lymphovenous anastomosis vascularized lymphatic transplant before but without sufficient volume reduction. The...

Primary lymphedema is usually caused by intrinsic disruption or genetic damage to the lymphatics but may also be result of age-related deterioration lymphatics. The aims this study were determine characteristics and assess effectiveness lymphaticovenous anastomosis (LVA) in its treatment.Eighty-six patients with primary affecting 150 lower limbs divided into three groups according whether age onset was younger than 35 years, 35-64 65 years older. Indocyanine green (ICG) lymphography...

Lymphaticovenous anastomosis (LVA) is now a common treatment for lymphedema. It important to create as many bypasses possible maximize the efficacy of LVA. We have developed method whereby nylon monofilaments are placed inside vessel lumen act dilators. refer this technique mechanical dilation (MD) distinguish it from intravascular stenting. In study, we investigated conventional supermicrosurgery performed with and without MD lower limb The LVA was using alone in 10 patients (group MD)...

There is limited information on postoperative care after liposuction for lymphedema limb. The aim of this retrospective study was to identify the threshold compression pressure and other factors that lead lower limb success.Patients were divided according whether they underwent therapy with both stockings bandaging (SB group), alone (S or (B group) 6 months liposuction. rate improvement compared method. We also investigated it possible decrease months. Liposuction considered successful if...

Several treatment options, including sclerotherapy and surgical excision, are available for the management of cystic lymphangioma. Lymphaticovenular anastomosis (LVA) has recently garnered attention in field microsurgery as a minimally invasive reconstruction strategy. Combined using excision LVA large or persistent lymphatic malformations been reported but can be very invasive. This case report describes use combination to treat with satisfactory results. could complementary extensive...

We describe a dementia patient with comorbid recurrent cellulitis and lymphedema in the left lower limb who was treated successfully for by lymphaticovenular anastomosis (LVA). The patient, an 83-year-old woman, suffered from three times year on average 15 years. Compression therapy impossible because of dementia. After LVA, there has been no recurrence 2 years.It is difficult to administer decongestive lymphatic some patients, such as patients LVA promising treatment lymphedema.

Background: Treatment for patients with comorbid lymphedema and varicose veins is controversial. Surgical options these are limited. The study was aimed to investigate the validity of combined lymphovenous anastomosis (LVA) great saphenous vein stripping (GSVS) veins. Methods: Thirteen were involved in study, detail 21 edematous lower limbs (with coexisting lymphedema; [VL] group) who underwent GSVS LVA therapy. Fifteen 30 only; [L] only included as a control group. performed before VL...

原発性虫垂癌は比較的まれな疾患であり,自覚症状も乏しいため,診断時には進行癌であることが多い.今回われわれは,虫垂憩室の後腹膜穿通を契機に比較的早期に発見された原発性虫垂癌の1例を経験したので報告する.患者は72歳の女性.右下腹部痛を主訴に来院した.腹部CT検査で急性虫垂炎の穿孔による腹腔内膿瘍と診断し手術を施行した.術中所見では虫垂が後腹膜と癒着し膿瘍を形成していた.虫垂の高度な壁肥厚と膿の性状より虫垂腫瘍を否定できず,また虫垂切除断端の安全な処理が困難と判断したため回盲部切除術を施行した.病理組織学的に虫垂間膜側の憩室穿孔と粘膜下層に浸潤する乳頭腺癌を認め,憩室が癌による内腔の閉塞に伴う内圧の上昇により後腹膜に穿通し膿瘍形成したものと診断した.併存した虫垂間膜の膿瘍腔内に癌細胞を認めたため,術後補助化学療法を施行しつつ外来にて経過観察中であるが,30カ月経過した現在無再発生存中である.

Despite advances in supermicrosurgical techniques, the ability to anastomose vessels with a diameter of less than 0.2 mm remains limited. One reasons for this limitation is that dilation methods currently available, such as inserting tip microforceps into lumen or topical application vasodilator papaverine hydrochloride xylocaine spray, are not effective very small vessels. To overcome problem, we have developed method whereby nylon monofilaments placed inside vessel act dilator. Using...

Flow-through flaps, wherein two or more flaps are placed in series using microvascular anastomoses, indicated for the coverage of longer and wider defects, typically extremities.These technically demanding but, importantly, associated with distal flap loss.To overcome these problems, 'Orochi' concept placing multiple parallel as part a modular reconstruction has been put forward.In this article, is illustrated cases extremity use sequential triple thoracodorsal perforator (TAP)-intercostal...

Summary: Rheumatoid lymphedema is a rare but severely disabling condition caused by reduced lymphatic drainage. Most treatment methods are conservative and may lead to the exacerbation of lymphedema. Lymphatic venous anastomosis (LVA) an effective for after surgery involving system, such as lymph node dissection cancer treatment. LVA has not been used treat rheumatoid We present case treated with surgical procedures, including LVA. Following LVA, objective subjective symptom relief was...

INTRODUCTION Lymphatic venous anastomosis (LVA) requires manipulation of the lymphatic channel and veins with diameters 0.3–0.8 mm, which is called supermicrosurgery.1,2 However, sometimes, surgeon finds only approximately 0.2 mm in surgical field. Despite advances supermicrosurgical techniques, vessels a diameter still challenging.3 The lumen obscured because transparency wall, whereas visibility lumens small arteries high. In addition, has flabby nature, making LVA difficult. Intravascular...