- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Cancer-related molecular mechanisms research
- Dermatology and Skin Diseases
- Skin Protection and Aging
- melanin and skin pigmentation
- Ferroptosis and cancer prognosis
- Dermatologic Treatments and Research
- Acne and Rosacea Treatments and Effects
- Liver Disease Diagnosis and Treatment
- MicroRNA in disease regulation
- interferon and immune responses
- Nanoplatforms for cancer theranostics
- Autophagy in Disease and Therapy
- Allergic Rhinitis and Sensitization
- Wound Healing and Treatments
- Cutaneous lymphoproliferative disorders research
- Antimicrobial agents and applications
- Plant-Microbe Interactions and Immunity
- Nail Diseases and Treatments
- Nutrition and Health in Aging
- RNA modifications and cancer
- Glutathione Transferases and Polymorphisms
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
Zhejiang Provincial People's Hospital
2016-2025
Hangzhou Medical College
2017-2025
North Sichuan Medical University
2025
Bengbu Medical College
2022-2024
Hangzhou Xixi hospital
2021
Suzhou Vocational University
2014
Wuzhou University
2013
Second Military Medical University
2008
Stony Brook University
2007
cryptococcus neoformans (C. neoformans) is a crucial opportunistic fungus that possesses an encapsulated fungal pathogen. The cryptococcal capsule mainly composed of the polysaccharide glucuronoxylomannan (GXM). Macrophages form first-line innate defense against cryptococcosis; however, underlying mechanism remains unclear. In this study, GXM-treated RAW264.7 macrophages showed notably reduced survival rate and increased apoptosis, accompanied by promoted inducible nitric oxide synthase...
Background: Prior studies have suggested a significant connection between fasting insulin (FI) and androgenetic alopecia (AGA), but the exact cause of this underlying molecular mechanism has not been clarified. In study, Mendelian randomization (MR) analysis was utilized to discover causal associations FI AGA. Methods: Genome-wide association study (GWAS) data for AGA were retrieved, bidirectional MR conducted. FI-associated genes identified through expression quantitative trait loci (eQTL)...
Rosacea, an inflammatory skin disorder with complex pathogenesis, remains poorly understood. Through integrative bioinformatics and experimental approaches, we identified 304 differentially expressed genes in erythrotelangiectasia rosacea (ETR), primarily enriched lipid metabolism pathways. Support vector machine (SVM), linear regression analyses network analysis revealed ACADVL ACSL5 as potential therapeutic targets. Immunological profiling demonstrated distinctive immune cell infiltration,...
Dysregulated microRNA (miR)-625 expression has been observed in several kinds of cancer. MicroRNAs are important factors the development and progression malignant melanoma, though clinical significance function miR-625 human melanoma remain unclear. Levels were therefore determined 36 pairs adjacent non-tumor tissue using qPCR. The effects dysregulation on cell proliferation, wound healing, migration invasion vitro tumorigenicity vivo investigated CCK-8, transwell assays, a nude mouse...