- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Knee injuries and reconstruction techniques
- Minimally Invasive Surgical Techniques
- Tendon Structure and Treatment
- Urinary Bladder and Prostate Research
- Epigenetics and DNA Methylation
- Metabolism and Genetic Disorders
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Pelvic floor disorders treatments
- Ferroptosis and cancer prognosis
- Glutathione Transferases and Polymorphisms
- Silk-based biomaterials and applications
- Orthopedic Surgery and Rehabilitation
- Cancer Genomics and Diagnostics
- Urological Disorders and Treatments
- Renal and Vascular Pathologies
- Hip disorders and treatments
- Urinary and Genital Oncology Studies
- Nutrition, Genetics, and Disease
- Vascular anomalies and interventions
- Inflammatory Bowel Disease
Hangzhou Medical College
2021-2025
Zhejiang Provincial People's Hospital
2021-2025
Second Affiliated Hospital of Zhejiang University
2016-2025
Shaoxing University
2023-2024
Shaoxing People's Hospital
2018-2024
Ruijin Hospital
2021-2024
Shanghai Jiao Tong University
2022-2024
Huadong Hospital
2005-2024
Fudan University
2024
Second Military Medical University
2009-2021
Abstract Real‐time monitoring wound status and providing timely therapies with smart dressing is a promising way to treat infections accelerate the healing process. Herein, establish closed‐loop treatment system, fully integrated, battery‐free, wireless for infection detection on‐demand drug delivery developed using flexible electronics. The integrated near field communication module can realize power harvest data transmission, on‐site signal processing, control, through miniaturized circuit...
The objective of this study was to investigate the potency platelet-rich plasma (PRP) combined with bone marrow mesenchymal stem cells (BMSCs) promote tendon–bone healing in a rabbit model. In vitro study, effects PRP on osteogenic induction BMSCs were analysed. Later, or without used model anterior cruciate ligament reconstruction. Specimens harvested 8 weeks postoperatively evaluate by histology, radiology, and biomechanical testing. revealed that collagen I, osteocalcin, osteopontin...
cryptococcus neoformans (C. neoformans) is a crucial opportunistic fungus that possesses an encapsulated fungal pathogen. The cryptococcal capsule mainly composed of the polysaccharide glucuronoxylomannan (GXM). Macrophages form first-line innate defense against cryptococcosis; however, underlying mechanism remains unclear. In this study, GXM-treated RAW264.7 macrophages showed notably reduced survival rate and increased apoptosis, accompanied by promoted inducible nitric oxide synthase...
Abstract Background Alterations of iron metabolism in Crohn's disease (CD) adversely affect patients’ quality life, with anaemia being a main clinical manifestation. The causes CD are multifaceted. Our goal is to outline the initial features treatment-naïve cohort, offering insights enhance therapeutic approaches. Methods We enrolled patients from prospective inception cohort between July 2019 and June 2022 undergoing treatment tumour necrosis factor antagonists collected results blood...
No AccessJournal of UrologyAdult Urology: Oncology: Prostate/Testis/Penis/Urethra1 Nov 2005MANAGEMENT OF PROSTATE CANCER IN CHINA: A MULTICENTER REPORT 6 INSTITUTIONS MICHAËL PEYROMAURE, BERNARD DEBRÉ, KAILI MAO, GUOQIANG ZHANG, YIRAN WANG, ZHONGQUAN SUN, DANFENG XU, JUN JIANG, and YINGHAO SUN PEYROMAUREMICHAËL PEYROMAURE , DEBRÉBERNARD DEBRÉ MAOKAILI MAO ZHANGGUOQIANG ZHANG WANGYIRAN WANG SUNZHONGQUAN XUDANFENG XU JIANGJUN JIANG SUNYINGHAO View All Author...
Abstract Background To investigate osteointegration at the graft-bone interface and prevention of osteoarthritis after anterior cruciate ligament (ACL) reconstruction using a silk-collagen scaffold with both ends modified by hydroxyapatite (HA) in rabbit model. Methods The HA/silk-collagen was fabricated degummed, knitted silk scaffold, collagen I matrix, simulated body fluid (SBF). rolled up to make graft for replacing native ACL experimental group (HA group), used control (S group). All...
Abstract Introduction Nutcracker syndrome (NCS) is caused by a compression of the left renal vein between aorta and superior mesenteric artery (SMA). It results in venous hypertension, subsequent development varicosities pelvis, ureter, gonadal vein. Case presentation A 21-year-old Chinese woman was admitted with seven-month history unilateral severe hematuria. On admission, she identified as having nutcracker syndrome. The patient treated retroperitoneal laparoscopic donor nephrectomy...
Abstract BACKGROUND: The role of microsatellite alterations in surgically excised tumors predicting the prognosis patients with clear cell renal carcinoma (ccRCC) remains largely unknown. METHODS: Specimens from 93 sporadic ccRCC were used to screen using 12 markers on chromosomes 3p, 9p, and 14q according disease stage. Survival was evaluated by Kaplan‐Meier method Cox regression analysis. expression targeted genes examined quantitative reverse transcriptase‐polymerase chain reaction...
Background Transurethral resection of the bladder tumor (TURBT) remains gold standard for non-muscle-invasive cancer (NMIBC). Laser techniques have been widely used in urology. This analysis aimed to assess safety and efficacy holmium (HoLRBT) vs. TURBT. Methods A systemic search MEDLINE, Embase, Web Science, The Cochrane Library as well manual bibliography searches were performed identify relevant studies. pooled estimates operation time, obturator nerve reflex rate, perforation irrigation...
Abstract Ultraviolet (UV) irradiation significantly contributes to photoaging. Ferroptosis, an iron-dependent cell death mode recently identified, plays a key role in UVB-induced skin This study examines the functions and regulatory mechanisms of ferroptosis this regard. Characterized by increased intracellular iron reactive oxygen species (ROS), is associated with mitochondrial function structure. Through RNA sequencing, we identified NADH: ubiquinone oxidoreductase subunit S4 (NDUFS4),...
Abstract Objective To assess whether systemic lupus erythematosus (SLE) may be genetically causally associated with migraine, including the two primary subtypes: migraine aura (MWA) and without (MWoA). Background The association between SLE has been investigated extensively. Previous studies have shown a higher prevalence of in patients SLE, although exact relationship remains unclear. This study potential causal using powerful analytical tool Mendelian randomization (MR). Methods We...
This study aimed to evaluate the clinical utility of 18F-PSMA-1007 positron emission tomography (PSMA PET)/magnetic resonance imaging (MRI) in patients with suspected or defined prostate cancer.In pilot study, we retrospectively investigated 62 who underwent PSMA-PET/MRI for PCa between June 2019 and 2020. Patients were grouped into three subgroups: (1) without histological evidence, (2) primary PCa, (3) biochemical recurrent cancer (BRPCa). Two nuclear physicians independently interpreted...
To determine the prevalence of dysfunctional voiding (DV) in female stress urinary incontinence (SUI) and its modification after tension-free vaginal tape (TVT) procedure.Three hundred sixty women with SUI were enrolled underwent urodynamics from 2002 to 2008. DV was determined when non-neurogenic detrusor-sphincter dyssynergia occurred during voluntary voiding. It further quantitatively analyzed using tense/loose value, a parameter derived external anal sphincter electromyogram. The...
Microbubbles magnify the acoustic pressure of low-intensity pulsed ultrasound (LIPUS) and may enhance its bioeffect for diagnostic therapeutic purposes. This study compared effect this novel microbubble-mediated (MUS) with that traditional LIPUS on osteogenesis neovascularization in a rabbit model steroid-associated osteonecrosis. We hypothesized MUS might outweigh promoting The bilateral femoral head necrosis was induced by lipopolysaccharide methylprednisolone rabbits. indices bone mineral...
Abstract We conducted this study to report on our initial experience and assess the safety, feasibility, efficacy of extraperitoneal single plus one port laparoscopic radical prostatectomy (SPOPL‐RP), determine whether it shows any objective advantage over standard prostatectomy. From June 2009 September 2011, 15 SPOPL‐RPs were performed through a 2–3‐cm subumbilical longitudinal incision another 5‐mm trocar placed at McBurney point. This cohort was compared with 37 contemporary patients who...