Jie Chen

ORCID: 0000-0001-8569-3667
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Circular RNAs in diseases
  • Legume Nitrogen Fixing Symbiosis
  • Cancer Genomics and Diagnostics
  • Genomic variations and chromosomal abnormalities
  • Insect symbiosis and bacterial influences
  • Polymer-Based Agricultural Enhancements
  • Insect Resistance and Genetics
  • Lipid metabolism and disorders
  • Genetic and phenotypic traits in livestock
  • Insect-Plant Interactions and Control
  • Gut microbiota and health
  • Clay minerals and soil interactions
  • Breast Lesions and Carcinomas

Guangdong Academy of Agricultural Sciences
2021-2023

Fujian Agriculture and Forestry University
2023

Institute of Plant Protection
2023

Sun Yat-sen University
2020-2021

Nanjing University of Chinese Medicine
2021

Sun Yat-sen Memorial Hospital
2020

Pingxiang University
2019

Southern Medical University
2019

Zhejiang Hospital
2019

First Affiliated Hospital of Nanchang University
2018

Rationale: The forkhead box A1 (FOXA1) is a crucial transcription factor in initiation and development of breast, lung prostate cancer. Previous studies about the FOXA1 transcriptional network were mainly focused on protein-coding genes. Its regulatory long non-coding RNAs (lncRNAs) their role oncogenic activity remains unknown. Methods: Cancer Genome Atlas (TCGA) data, RNA-seq ChIP-seq data used to analyze regulated lncRNAs. RT-qPCR was detect expression DSCAM-AS1, Western blotting...

10.7150/thno.47830 article EN cc-by Theranostics 2020-01-01

The incorporation of green and sustainable nanomaterials in pesticide formation is an effective method to lower the use conventional pesticides without adverse effects on productivity. Here Pickering emulsions stabilized by halloysite nanotubes (HNTs) were developed for low cost, less environmental pollution, toxic effects, better emulsion stability. HNTs added chlorantraniliprole (CAP) emulsions, good stability was exhibited due adsorption aggregation at interface CAP oil droplets, forming...

10.1021/acsami.2c11234 article EN ACS Applied Materials & Interfaces 2022-08-30

Abstract The fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is a destructive pest that causes serious damage worldwide, particularly to maize cultivars. microbiota of S. might play role in its development and adaptability different environments. However, the dynamics microbial communities during life cycle remain poorly understood. In this study, we used amplification 16S rRNA gene characterize microbiome all developmental stages fed with adults an artificial...

10.1111/eea.13282 article EN Entomologia Experimentalis et Applicata 2023-02-03

Abstract Fibroadenomas (FAs) are the most common fibroepithelial lesions and benign tumors of breast in women reproductive age. Although MED12 mutations, an overwhelming majority all some other gene mutations have been found FAs, genomic landscapes FAs still not completely clear mutation spectrums Chinese population remains unknown. Here, by performing whole exome sequencing 12 corresponding normal tissues Han population, we observed somatic germline genetic alterations. We identified 16...

10.1002/cam4.2081 article EN cc-by Cancer Medicine 2019-03-09

Abstract The insulin signalling pathway plays a crucial role in regulating the metabolism of sugars, fats and proteins cells, thereby affecting growth, metabolism, reproduction ageing organisms. However, little is known about functions long non‐coding RNAs (lncRNAs) regulation receptors under stress conditions insects. In this study, we showed that receptor‐associated lncRNA (IRAR) regulates receptor transcripts response to nutritional Drosophila melanogaster . Genome editing by CRISPR‐Cas9...

10.1111/imb.12756 article EN Insect Molecular Biology 2021-12-19

10.1016/j.tem.2023.10.003 article EN Trends in Endocrinology and Metabolism 2023-10-01

Long chain non-encoding RNA (lncRNA) can affect gene expression through transcription, post transcriptional regulation and epigenetic modification, it is involved in regulating ovarian physiological function. LncRNA, as a competitive endogenous RNA, the of target mRNA by competitively binding microRNA (miRNA), which are called lncRNA/miRNA/mRNA regulatory network. It plays an important role function occurrence development reproductive disorders, expecting to become new diagnostic index for...

10.11817/j.issn.1672-7347.2021.200622 article EN Zhongnan Daxue xuebao. Yixue ban 2021-07-28
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