- Research on Leishmaniasis Studies
- Veterinary Medicine and Surgery
- Animal health and immunology
- Pancreatitis Pathology and Treatment
- Leptospirosis research and findings
- Veterinary Oncology Research
- S100 Proteins and Annexins
- Paraoxonase enzyme and polymorphisms
- Iron Metabolism and Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Streptococcal Infections and Treatments
- Intestinal and Peritoneal Adhesions
- Bird parasitology and diseases
- Trypanosoma species research and implications
- Immune Response and Inflammation
- Veterinary Equine Medical Research
- Food Allergy and Anaphylaxis Research
- Abdominal Trauma and Injuries
- Herpesvirus Infections and Treatments
- Dermatological diseases and infestations
- Clusterin in disease pathology
- Ectopic Pregnancy Diagnosis and Management
- Salivary Gland Disorders and Functions
- Vitamin C and Antioxidants Research
- Hereditary Neurological Disorders
Universidad de Murcia
2014-2025
Abstract The aim of this study was to evaluate the changes in serum and salivary inflammatory markers induced by Diabetes mellitus (DM) dogs assess possible confounding effect gingivitis. A panel 13 cytokines measured saliva diagnosed with DM compared healthy without gingivitis (control group 1; CG1) but otherwise 2; CG2). results present showed statistically significantly higher levels IL-8, KC-like MCP1 CG1 dogs. In case saliva, presented GM-CSF, IL6, IL15, CG1, lower chemokine CG2....
Obesity is defined as the excessive accumulation of adipose tissue and currently most common disease in cats. Similarly to humans, obesity negatively impacts health welfare cats, predisposing them many other disorders. The objective this study was compare serum proteomes normal-weight overweight/obese aiming gain insights into physiopathology feline potentially identify new biomarkers. For this, samples from a total 20 adult neutered domestic shorthair client-owned ten normal weight...
A validation of a species-specific enzyme immunoassay for urinary clusterin measurement in dogs was performed, and the use as marker renal damage evaluated population with leishmaniasis. Urine obtained from 75 dogs; 64 had leishmaniasis 11 were healthy. The leishmanias divided into 5 groups: I ( n = 9; serum creatinine [SCr] < 1.4 mg/dl, protein-to-creatinine [UPC] ratio ≤ 0.5); II 29; SCr UPC > III 6; ≥ mg/dl to <2 IV 13; 2 <5 V 7; 0.5). concentration measured,...
Determination of acute phase proteins and markers oxidative status may be value for evaluating the severity disease response to treatment. In canine demodicosis, there is no information available regarding use such analytes discriminate between localized generalized demodicosis or monitor treatment.The aim was measure related inflammation stress in dogs with demodicosis. cases intention study these before after a period treatment.Serum obtained from three groups: Group 1, healthy dogs; 2,...
Serum paraoxonase 1 is considered a marker of inflammation and oxidative damage. The aims this study were to evaluate changes in serum activity dogs with acute pancreatitis, correlate other analytes known be altered pancreatitis assess the relationship between disease severity pancreatitis.Retrospective analysis healthy which was measured compared.Median significantly lower (n = 19) compared ones 19). negatively correlated lipase amylase activities, C-reactive protein haptoglobin...
The objective of this study was to evaluate and compare the evolution profile currently recommended by International Renal Interest Society (IRIS) (sCr, UPC sSDMA) with a panel other different kidney biomarkers during treatment for canine leishmaniosis. This included three urinary glomerular (uIgG, uCRP uferritin) tubular (uGGT, uNAG uRBP). These were measured in two groups dogs leishmaniosis at IRIS stage I. Group 1: showing proteinuria (UPC > 0.5) before which did not decrease after...
Background Measurement of salivary adiponectin could improve understanding this adipokine's physiology, and its role in various clinical conditions. Objectives The purpose the study was to evaluate utility a human ELISA kit for measurement dogs, compare serum concentrations healthy dog population, possible effects tooth‐cleaning on dogs. Methods For analytical validation, precision, accuracy, lower limit quantification assay were determined with saliva samples. In addition, quantified...
In the current study, quantification of C-reactive protein (CRP) in cerebrospinal fluid (CSF) dogs using an adapted time-resolved immunofluorimetric assay (TR-IFMA) was investigated, as well whether could be used to detect range CRP concentrations found different clinical situations. Intra- and interassay coefficients variation were below 15% all cases. The TR-IFMA measured values a proportional linear manner (r = 0.99); also CSF serum significantly correlated 0.80, P 0.003). limit detection...
Urea and creatinine in saliva have been reported to be possible markers of chronic kidney disease (CKD) humans. The aim this study was assess if urea could measured canine saliva, evaluate their changes situations CKD. spectrophotometric assays for measurements dogs showed intra- inter-assay imprecision lower than 12% coefficients correlation close 1 linearity under dilution tests. Healthy median salivary concentrations 39.6 mg/dL 0.30 mg/dL, whereas with CKD 270.1 1.86 mg/dL. Positive high...
We evaluated the acute phase protein response in capybaras (Hydrochoerus hydrochaeris). Three animal groups were used: 1) healthy animals (n=30), 2) a group which experimental inflammation with turpentine was induced (n=6), and 3) affected sarcoptic scabies (n=14) 10 treated ivermectin. Haptoglobin (Hp), acid-soluble glycoprotein (ASG) albumin analyzed all animals. In those turpentine, Hp reached its maximum value at 2 wk 2.7-fold increase, whereas ASG increased 1.75-fold decreased 0.87-fold...
Summary This investigation was carried out on 64 healthy adult competition pigeons (Spanish Poulers) to determine reference values of electrocardiographic parameters in standard lead II; a comparative study between males and females also performed find changes the patterns related sex. P wave positive monophasic; PR segment depression present 64% records; QRS pattern obtained most cases rS type, followed by QS configuration. ST slurring (absence ST) observed 47% records mean electrical axis...
Abstract Green periurban residential areas in Mediterranean countries have flourished the last decades and become foci for leishmaniasis. To remedy absence of information on vector ecology these environments, we examined phlebotomine sand fly distribution 29 sites Murcia City over a 3-year period, including plots 20 detached houses nine non-urbanized nearby. We collected 5,066 specimens from five species using “sticky” interception light attraction traps. The relative frequency main...
ABSTRACT We describe an atypical case of duodenal leishmaniasis in a boxer dog presenting with chronic diarrhea and poor general condition. Antidiarrheic therapy was previously administered without success inflammatory bowel disease localized to the small intestine suspected, given clinical signs by ruling out other known causes gastrointestinal inflammation. Endoscopic biopsy duodenum showed moderate increase lamina propria lymphocytes, plasma cells, macrophages. Basophilic bodies were seen...
Acute-phase proteins (APPs) are biomarkers of systemic inflammation, which allow monitoring the response to surgery and post-operative complications. Ovariectomy (OVE) can be a useful model evaluate surgical trauma inflammation in feline species. The objective this study was compare acute-phase (APR) after applying two different OVE techniques by measuring serum levels amyloid A (SAA), haptoglobin (Hp), total (TSPs), albumin (ALB), paraoxonase-1 (PON-1) during first 48 h post-surgery...
Canine obesity is the most common nutritional disorder and associated with decreased quality of life longevity as well comorbidities including cardiorespiratory, endocrine, oncologic, or orthopaedic disorders. Ferritin a major acute-phase protein in dogs, increasing during inflammation; however, it could also be affected by other conditions, trauma, iron metabolism dysregulations, neoplasia, hypoxia. Higher ferritin levels have been reported obese humans, but has not explored canine obesity....
Abstract A six‐year‐old neutered male Labrador Retriever was presented with haematuria and inappetence of one‐week duration. Physical examination revealed mild abdominal pain the blood cell count showed moderate polycythaemia, a slight increase erythropoietin levels. Urinalysis demonstrated proteinuria, isosthenuria urinary sediment amount lymphoid cells. After performing complete imaging study (radiographs, ultrasound CT scan), unilateral renal lymphoma secondary extranodal tract (bladder...