A5002088385- Veterinary Equine Medical Research
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Exercise and Physiological Responses
- Pharmacological Effects and Assays
- Reproductive Physiology in Livestock
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Cardiovascular Disease and Adiposity
- Peroxisome Proliferator-Activated Receptors
- Meat and Animal Product Quality
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- Gastroesophageal reflux and treatments
- Animal Nutrition and Physiology
- Antibiotics Pharmacokinetics and Efficacy
- Atherosclerosis and Cardiovascular Diseases
- Heat shock proteins research
- Bacterial Identification and Susceptibility Testing
- Vitamin K Research Studies
- Animal Virus Infections Studies
- Selenium in Biological Systems
- Veterinary Pharmacology and Anesthesia
- Cardiac Arrhythmias and Treatments
- Muscle Physiology and Disorders
Universidad de Murcia
2012-2024
National Autonomous University of Honduras
2018
Santa Lucía University General Hospital
2008-2011
Hospital Universitario Virgen de la Arrixaca
2011
Hospital General Universitario Morales Meseguer
2011
Hospital General Universitario Santa María del Rosell
2008
Universidad Nacional Autónoma de México
2008
University of Puerto Rico System
1999
Universidade de Santiago de Compostela
1997-1998
Universidad Complutense de Madrid
1998
Changes in the salivary proteome 12 horses with two diseases included equine gastric ulcer syndrome (EGUS), glandular disease (EGGD) (n = 6) and squamous (ESGD) 6), were evaluated using a high-resolution LC-MS/MS analysis of TMT-labelled peptides compared to 10 healthy control horses. Serum was also analysed for comparative purposes. The comparison between EGGD controls showed significant changes proteins, whereas 36 proteins differently abundant ESGD groups. most upregulated case related...
Ammonia (NH3) and bicarbonate (HCO3) have been related to gastric ulcers in humans. is considered a possible cause of ulcers, whereas has protective function. The presence the stomach horses defined as Equine Gastric Ulcer Syndrome (EGUS), which frequent disease this species, it associated with changes saliva composition, such analytes inflammation, immune system oxidative stress. objectives study were (1) perform an analytical validation two automated spectrophotometric assays, one for...
Equine gastric ulcer syndrome (EGUS) is a highly prevalent disease that affects horses worldwide. Within EGUS, two different forms have been described: equine squamous (ESGD) and glandular (EGGD). The associated clinical signs cause detrimental activity performance, reducing the quality of life animals. Saliva can contain biomarkers for EGUS could be potentially used as complementary tool diagnosis. objective this work was to evaluate measurements calprotectin (CALP) aldolase in saliva...
Non-alcoholic steatohepatitis (NASH) is part of the spectrum non-alcoholic fatty liver disease (NAFLD), currently most common cause abnormal tests. Given difficulty studying all factors involved in it human populations, studies animal models might provide crucial insights pathogenesis steatohepatitis. Several physiological features predispose birds to fat deposition liver. The present study was conceived explore possibilities chicken fed a cholesterol and enriched diet as model for We used...
Changes in the oxidative status of blood horses suffering from gastric ulcers and colic intestinal aetiology (CIE) have been reported. However, saliva can also be a source biomarkers status. Therefore, this study aims to validate automated assays for measurement (ferric reducing ability saliva/serum-FRAS/FRAP, cupric antioxidant capacity-CUPRAC, Trolox equivalent capacity-TEAC, uric acid, advanced oxidation protein products-AOPP) serum horses, assess their changes different ulcer diseases...
Long-term benefits of initiating stroke prophylaxis in the emergency department (ED) are unknown. We analyzed long-term safety and ED prescription anticoagulation atrial fibrillation patients.Prospective, multicenter, observational cohort consecutive patients was performed 62 Spanish EDs. Clinical variables thromboprophylaxis prescribed at discharge were collected inclusion. Follow-up 1 year post-discharge included data about its complications, major bleeding, death; risk assessed with...
Equine gastric ulcer syndrome (EGUS) is currently one of the more frequent diseases in horses. We aimed to identify changes salivary proteome horses with EGUS at diagnosis and after successful treatment by using gel proteomics. Saliva samples were collected from nine before matched healthy controls. SDS-PAGE (1DE) two-dimensional electrophoresis (2DE) performed, significantly different protein bands spots identified mass spectrometry. Horses had increases proteins such as adenosine deaminase...
Salivary biomarkers could be useful to evaluate stress, fitness level, and skeletal muscle damage associated exercise in horses an easy non-painful way. Therefore, this study aims if cortisol saliva (sCor), salivary alpha-amylase (sAMY) butyrylcholinesterase (sBChE) lactate (sLA) creatine kinase (sCK) of can show changes during a standardized test, they are related heart rate variability (HRV) parameters sympathetic parasympathetic tone, level or damage. For purpose, ten endurance were...
The mean duration and amplitudes of the lead II electrocardiogram were determined in peregrine falcon (Falco peregrinus brookei) using 10 birds ranging age from 1 to 5 yr. Electrocardiograms performed on unanesthetized falcons order avoid anesthesia effect electrocardiogram, by a method which seems induce tonic immobility–like reaction. All had normal sinus rhythm, with heart rate 268 beats per minute. Mean durations PR, ST, QT, RR intervals higher (but not statistically significant) females...
Danofloxacin is a fluoroquinolone developed for veterinary medicine showing an excellent activity. However, danofloxacin pharmacokinetics profile have not been studied in horses previously.To study the following i.v., i.m. and intragastric (i.g.) administration of 1.25 mg/kg bwt to 6 healthy horses.A cross-over design was used 3 phases (2 x 2 2), with washout periods 15 days (n = 6). (18%) administered by i.v. routes at single doses bwt. For i.g. oral solution prepared via nasogastric tube....
Summary This investigation was carried out on 64 healthy adult competition pigeons (Spanish Poulers) to determine reference values of electrocardiographic parameters in standard lead II; a comparative study between males and females also performed find changes the patterns related sex. P wave positive monophasic; PR segment depression present 64% records; QRS pattern obtained most cases rS type, followed by QS configuration. ST slurring (absence ST) observed 47% records mean electrical axis...
Abstract Objective —To study the pharmacokinetics of difloxacin (5 mg/kg) following IV, IM, and intragastric (IG) administration to healthy horses. Animals —6 mature Procedures —A crossover design with 3 phases was used (15-day washout periods between treatments). An injectable formulation (5%) administered IV IM in single doses mg/kg); for IG administration, an oral solution prepared via nasogastric tube. Blood samples were collected before at intervals after each administration. A...
The duration of electrocardiograph wave forms and intervals were determined in 179 Spanish-bred (Andalusian) horses aged from 1 month to 17 years. values compared with those other breeds, the relationship between electrocardiographic data age was examined. High correlation coefficients found PR, ST QT horses, an inverted relation heart rate found. A multiple range analysis made results suggest that significant changes occurred at 6 months second year life.
Calcium appears to be involved in many of the cellular events which are thought important atherogenesis. channel blockers have been shown reduce arterial lipid accumulation animals without altering serum cholesterol. Avian models atherosclerosis offer economic and technical advantages over mammalian models. In this study, we examine effects nifedipine, verapamil diltiazem at clinical higher doses, on extent egg-fed chickens. order assess quantitatively, aortic lesions thoracic abdominal...
ABSTRACT We describe an atypical case of duodenal leishmaniasis in a boxer dog presenting with chronic diarrhea and poor general condition. Antidiarrheic therapy was previously administered without success inflammatory bowel disease localized to the small intestine suspected, given clinical signs by ruling out other known causes gastrointestinal inflammation. Endoscopic biopsy duodenum showed moderate increase lamina propria lymphocytes, plasma cells, macrophages. Basophilic bodies were seen...
High levels of circulating lipids contribute to both the development non-alcoholic liver steatosis (NALS) and peripheral arterial disease, leading increased thrombotic risk. However, effects hyperlipidemia on hepatic proteins have barely been studied. Antithrombin is a serpin with anticoagulant anti-inflammatory roles. The conformational flexibility antithrombin renders it susceptible both, genetic posttranslational modifications. Thus, mutations environmental factors shown alter this...