- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Bariatric Surgery and Outcomes
- Pancreatic and Hepatic Oncology Research
- Inflammatory Biomarkers in Disease Prognosis
- Congenital Diaphragmatic Hernia Studies
- Minimally Invasive Surgical Techniques
- Gastrointestinal Tumor Research and Treatment
- Oral microbiology and periodontitis research
- Metastasis and carcinoma case studies
- Hip and Femur Fractures
- Gastroesophageal reflux and treatments
- Gallbladder and Bile Duct Disorders
- Genetic factors in colorectal cancer
- Pelvic and Acetabular Injuries
- Viral-associated cancers and disorders
- Oral and gingival health research
- Stoma care and complications
- Colorectal Cancer Screening and Detection
- Gynecological conditions and treatments
University of Medicine and Pharmacy of Craiova
2015-2025
University of Craiova
2021-2025
Carol Davila University of Medicine and Pharmacy
2024
County Hospital
2024
Aristotle University of Thessaloniki
2021
Clinical Emergency Hospital Bucharest
2019
Neutrophil/lymphocyte ratio (NLR) is known as a prognostic for the outcome of patients with gastric cancer. As no definite risk marker anastomotic leakage after resection was identified, we investigated possible role NLR.
The treatment of pancreatic cancer represents a major objective in clinical research, as it still remains the fourth leading cause deaths among men and women, with approximately 6% all cancer-related deaths.We studied assessment an endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) probe through 19G needle order to achieve desirable necrosis area pancreas. Radiofrequency head pancreas was performed on 10 Yorkshire pigs weight between 25 kg 35 length 40-70 cm. Using EUS-guided...
Colorectal cancer (CRC) is one of the most widespread malignancy, posing as a great challenge due to its high incidence and mortality in both genders. Yet, it also stands preventable diseases because known malignant transformation mostly from tubular adenomas or serrated polyps, therefore offering strong incentive screening programs that are being developed for this disease. Current diagnosis CRC has surely evolved along with evolutionary step gastrointestinal technology flexible endoscopy....
Gastrointestinal stromal tumors (GIST) are a rare form of cancer located within the gastrointestinal (GI) tract, defined as with spindle, epithelioid, or occasionally pleomorphic cells. They originate in interstitial cells Cajal, function "pacemaker" motility. Their behavior is dictated by changes c-kit/PDGFRA gene, which often highlighted immunolabeling.
Parahiatal hernias (PHHs) are rare occurring disease, with a reported incidence of 0.2%-0.35% in patients undergoing surgery for hiatal hernia. We found only handful cases primary PHHs the literature. The aim this paper is to present case PHH and perform systematic review literature.We report 60-year-old Caucasian woman no history thoraco-abdominal or trauma, which accused epigastric pain, starting 2 years prior, pseudo-angina bloating. Based on imagistic findings patient was diagnosed an...
Schwannoma is a tumor that originates from the Schwann cells surround neuron's axon. This very rare in gastrointestinal tract and develops submucosally intestinal nerve plexuses. The most common location for schwannomas stomach, where they account only 0.2% of gastric tumors. We present case 56-year-old asymptomatic patient who was diagnosed, following routine ultrasound examination, with an abdominal tumor. An MRI confirmed origin Although subsequent upper-digestive endoscopic performed,...
Oral microbiota have shown a higher bacterial diversity in patients with cancers of the digestive tract, levels periopathogens. Recent studies that Fusobacterium links to gastro-intestinal neoplastic tissue and accelerates its progression, as well worsening patient outcome. The present pilot study was carried out between February December 2020 evaluate possible association abundance some periopathogens (Fusobacterium nucleatum, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans,...
Acute gastric remnant bleeding is an exceptionally rare complication when it occurs long after bariatric surgery. We present the case of a patient with ulcer excluded stomach (i.e., remnant), occurring 7 years Roux-en-Y bypass (RYGB) for morbid obesity. A computed tomography scan managed to locate active source in remnant. During emergency laparotomy, fundic region was identified. Total resection performed, good post-operative recovery. To best our knowledge, this first full report...
Minimal invasive surgical procedures such as laparoscopy are preferred over open surgery due to faster postoperative recovery, less trauma and inflammatory response, scarring. Laparoscopic repairs of hiatal hernias require pre-procedure planning ensure appropriate exposure positioning the ports for triangulation, ergonomics, instrument length operational angles avoid fulcrum effect long rigid instruments. We developed a novel navigation software, iMTECH determine optimal location skin...
EUS guided Natural Orifice Transluminal Endoscopic Surgery (NOTES) could be a potentially viable approach for pancreatic surgery. EUS-guided access through the stomach wall may prove to safe and effective method accessing pancreas. The aim of study was assess diagnostic therapeutic procedures during NOTES both anterior posterior pancreas.The feasibility peritoneoscopy an transgastric approach, as well direct pancreas tested ease tail Gastric wound closure finally performed in several animals...
Context: În timp ce repararea herniei ventrale este o intervenţie chirurgicală frecventă, posibilitatea apariţiei complicaţiilor rămâne prezentă.Utilizarea drenajelor pentru a preveni complicaţiile un subiect de dezbatere, cu dovezi contradictorii.Acest studiu îşi propune să evalueze asocierea dintre utilizarea şi postoperatorii în cura ventrale.Materiale Metode: Un prospectiv desfăşurat într-un singur centru inclus pacienţi care au suferit reparare perioada 2018-2022.Datele pacienţilor...
Diabetes mellitus (DM) and obesity are known to influence postoperative outcomes in surgical patients. This study aimed analyze the divergence between patients with without DM who underwent ventral hernia repair, while also assessing additional impact of on complications, hospitalization, costs. A prospective, non-interventional, observational was conducted over five years (2018-2022) at First Surgical Clinic Craiova Emergency Clinical Hospital. The included 216 patients, 42 (19.44%) having...
The validation of histological prognostic markers in colorectal cancer not only for survival parameters but also early postoperative outcomes is paramount importance. aim our study was to search the tumor histopathological (HP) characteristics that may influence morbidity, especially occurrence anastomotic leakage. Our results indicated peritumoral inflammatory cell infiltrate appeared correlate with both fistula and overall complications. Likewise, high-grade undifferentiated tumors seemed...
Uncontrolled bleeding contributes to 30% 40% of trauma-related deaths and is the leading cause potentially preventable deaths. Currently, there no effective method available first responders for temporary control noncompressible intraabdominal while patients are transported hospital. Our previous studies demonstrated that abdominal insufflation provides control. The study aims prove feasibility (insufflation a target pressure) safety (cardiovascular respiratory effects) novel portable device...
Acute pancreatitis is a pathological entity that poses numerous diagnostic and treatment problems. Severe form real challenge for physician because it has multiple obscure causes, as well complex pathophysiology. Thus, the diagnosis difficult choice of right time surgical controversial, being more frequently nonspecific, supportive various affected systems organs. On group 337 patients, laboratory imaging investigations were performed to diagnose determine severity score acute correlation...
Poor oral hygiene leads to the accumulation of dental plaque, thus contributing initiation periodontal disease (PD). Local infections can lead systemic inflammatory responses, which are essential mediators for evolution conditions or cancer tumorigenesis. Often, patients hospitalized with life-threatening and incapacitating disorders such as gastric (GC) might lose interest in keeping their mouth healthy. This study evaluates hygiene, status, need care medical personnel assist achieving it...
This study investigates the prognostic significance of carcinoembryonic antigen (CEA) levels in predicting early postoperative mortality patients who have undergone colorectal cancer surgery.