Octavio Dı́ez-Sales

ORCID: 0000-0003-4214-8567
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Dermatology and Skin Diseases
  • Bee Products Chemical Analysis
  • Lipid Membrane Structure and Behavior
  • Surfactants and Colloidal Systems
  • Contact Dermatitis and Allergies
  • Polysaccharides Composition and Applications
  • Drug Solubulity and Delivery Systems
  • Skin Protection and Aging
  • Essential Oils and Antimicrobial Activity
  • Ocular Surface and Contact Lens
  • Mangiferin and Mango Extracts
  • Antioxidant Activity and Oxidative Stress
  • Flavonoids in Medical Research
  • Curcumin's Biomedical Applications
  • Natural Compound Pharmacology Studies
  • Nanocomposite Films for Food Packaging
  • Analytical Methods in Pharmaceuticals
  • Rheology and Fluid Dynamics Studies
  • Toxin Mechanisms and Immunotoxins
  • Natural product bioactivities and synthesis
  • Olfactory and Sensory Function Studies
  • Thermodynamic properties of mixtures
  • Hydrogels: synthesis, properties, applications

Universitat Politècnica de València
2015-2024

Universitat de València
2015-2024

Centro Médico Sanitas Valencia
2017

Hôpital Purpan
2006

Context: Quercetin (QUE) is a flavonoid with antioxidant/anti-inflammatory properties, poorly absorbed when orally administered. Objectives: To prepare chitosan/xanthan gum microparticles to increase QUE oral bioavailability and optimize its release in the colon. Materials methods: Chitosan/xanthan hydrogel embedding was spray-dried obtain characterized by size, scanning electron microscopy, differential calorimetry X-ray diffraction. Microparticles were compressed into tablets, coated...

10.3109/02652048.2014.913726 article EN Journal of Microencapsulation 2014-06-06

Aim: The moisturizing properties of glycerol, the penetration enhancing capability propylene glycol and bioadhesive mucin were combined to improve carrier capabilities transfersomes efficacy mangiferin in treatment skin lesions. Materials & methods: Mangiferin was incorporated glycoltransfersomes, which also modified with mucin. physico–chemical features assessed, along against oxidative stress wounds vitro vivo. Results: Glycoltransfersomes promoted deposition epidermis dermis, protected...

10.2217/nnm-2020-0116 article EN cc-by-nc-nd Nanomedicine 2020-07-01

Pure alcohols or mixed with water are the most widely used solvents in a great variety of industrial applications, including formulation pharmaceutical and cosmetic products. As result water/alcohol molecular associations, variations physico-chemical characteristics system, such as density, viscosity, refractive index surface tension. The present study investigates tension ethanol mixtures at temperature 25°C, for different molar fractions. data obtained allow us to corresponding synergies;...

10.1080/00319100512331327342 article EN Physics and Chemistry of Liquids 2005-01-27

The effects of lipid concentration and composition on the physicochemical properties, aerosol performance in vitro toxicity activity several rifampicin-loaded liposomes were investigated. To this purpose, six liposome formulations containing different amounts soy phosphatidylcholine hydrogenated phosphatidylcholine, with without cholesterol oleic acid, prepared fully characterized. Uni- or oligo-lamellar, small (~100 nm), negatively charged (~60 mV) vesicles obtained. Lipid affected delivery...

10.3390/pharmaceutics4040590 article EN cc-by Pharmaceutics 2012-11-27

Water is the most widely used solvent in chemical and pharmaceutical industry, since it physiological best tolerated excipient. However, some cases water cannot be as a because active substance or solute insoluble only slightly soluble water. For this other reasons, nonwater solvents may possessing common characteristic of being mixable water; result, such can to prepare binary tertiary mixtures, etc., with different purposes increasing solubility, modifying viscosity absorption dissolved...

10.1080/00319100410001700850 article EN Physics and Chemistry of Liquids 2004-10-01
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