A5063005692- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Bone Tissue Engineering Materials
- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
Italian Institute of Technology
2025
Sapienza University of Rome
2025
Sabancı Üniversitesi
2021-2023
Recent advancements in tissue engineering have demonstrated a great potential for the fabrication of three-dimensional (3D) structures such as cartilage and bone. However, achieving structural integrity between different tissues fabricating interfaces are still challenges. In this study, anin situcrosslinked hybrid, multi-material 3D bioprinting approach was used hydrogel based on an aspiration-extrusion microcapillary method. Different cell-laden hydrogels were aspirated same glass...
The synergistic integration of microfluidic technologies with additive manufacturing systems is advancing the development innovative platforms to 3D bioprint scaffolds for tissue engineering unparalleled biological relevance. Significant interest growing in realizing porous functionally graded materials (pFGMs) that can resemble hierarchical organization porosity found bone tissue. This study introduces a method fabricating based on real-time generation liquid foam, which gelled, forming...
Abstract Sedimentation is the settling of solid particles in a liquid medium driven by gravity. This phenomenon poses significant challenges experimental lab-on-chip (LOC) applications, as they often involve biological sample to be loaded inside syringe for prolonged periods (e.g. 3D bioprinting, microfluidic cytometers). Mitigating solutions such mechanical agitators or buffer adjustments exist, but increase complexity and cost setup. In this work, we developed model particle sedimentation...
Abstract Recent studies on three-dimensional (3D) bioprinting of cell-laden gelatin methacryloyl (GelMA) hydrogels have provided promising outcomes for tissue engineering applications. However, the reliance use photo-induced gelation processes GelMA and lack an alternative crosslinking process remain major challenges fabrication structures. Here, we present a novel approach to form hydrogel constructs through 3D embedded without using any external irradiation that could drastically affect...
In this study, the acidity of urazole (pKa 5-6) was exploited to fabricate a hydrogel in two simple and scalable steps. Commercially available poly(hexamethylene)diisocyanate used as precursor synthesize an containing gel. The formation confirmed by FT-IR
In this study, highly ionazable protons (pKa 5-6) of urazole were exploited to obtain an anionic hydrogel in two simple and scalable steps. Commercially available multiisocyanate, poly(hexamethylene)diisocyanate, was used prepare containing gel. Urazole formation confirmed by FT-IR 1H-NMR spectroscopy. The characterized microscopy imaging, spectroscopic gravimetric analysis. Mechanical analysis cell viability test performed for its initial biocompatibility evaluation. prepared is a porous...
In this study, highly ionazable protons (pKa 5-6) of urazole were exploited to obtain an anionic hydrogel in two simple and scalable steps. Commercially available multiisocyanate, poly(hexamethylene)diisocyanate, was used prepare containing gel. Urazole formation confirmed by FT-IR 1H-NMR spectroscopy. The characterized microscopy imaging, spectroscopic gravimetric analysis. Mechanical analysis cell viability test performed for its initial biocompatibility evaluation. prepared is a porous...