A5102839218- Soil Carbon and Nitrogen Dynamics
- Environmental and Agricultural Sciences
- Hydraulic and Pneumatic Systems
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Pasture and Agricultural Systems
- Rangeland Management and Livestock Ecology
- Robot Manipulation and Learning
- Alzheimer's disease research and treatments
- Metabolomics and Mass Spectrometry Studies
- Forest, Soil, and Plant Ecology in China
- Neurological Disease Mechanisms and Treatments
- Lung Cancer Diagnosis and Treatment
- Plant Ecology and Soil Science
- Tunneling and Rock Mechanics
- Immune Response and Inflammation
- Structural Health Monitoring Techniques
- Hip and Femur Fractures
- Soil and Water Nutrient Dynamics
- Asthma and respiratory diseases
- Ruminant Nutrition and Digestive Physiology
- Cancer, Stress, Anesthesia, and Immune Response
- Agriculture, Soil, Plant Science
- Neurogenesis and neuroplasticity mechanisms
Jilin University
2021-2024
Wenzhou Medical University
2022-2024
Peking University
2024
Nanjing Medical University
2012-2024
Zhejiang Lab
2024
State Key Laboratory of Automotive Simulation and Control
2022-2023
First Affiliated Hospital of Wenzhou Medical University
2022
Kyoto University
2020
Suzhou Municipal Hospital
2010-2018
Lanzhou University
2007-2013
To evaluate the validity of two abbreviated protocols (AP) MRI in breast cancer screening dense tissue.This was a retrospective study 356 participants with tissue and negative mammography results. The approved by Nanjing Medical University Ethics Committee. Patients were imaged full diagnostic protocol (FDP) MRI. Two APs (AP-1 consisting first post-contrast subtracted [FAST] maximum-intensity projection [MIP] images, AP-2 AP-1 combined diffusion-weighted imaging [DWI]) FDP images analyzed...
Abstract Background Diabetic cardiomyopathy (DCM) is one of leading causes diabetes-associated mortality. The gut microbiota-derived branched-chain amino acids (BCAA) have been reported to play a central role in the onset and progression DCM, but potential mechanisms remain elusive. Results We found type 1 diabetes (T1D) mice had higher circulating BCAA levels due reduced degradation ability microbiota. Excess decreased hepatic FGF21 production by inhibiting PPARα signaling pathway thereby...
Objective To evaluate the application of abbreviated protocol (AP) magnetic resonance imaging (MRI) in screening breast cancer with dense tissue. Methods Total 478 patients tissue, who had negative X-ray mammography (MG), underwent dynamic contrast-enhanced MRI (DCE-MRI). The AP MRI, which consisted first postcontrast subtracted (FAST) and maximum-intensity projection (MIP), full diagnostic (FDP) images were analyzed by Breast Imaging Reporting Data System (BI-RADS). Among...
The drill pipe of a rotary rig is subject to the dynamic influence non-stationary loads, including rotation torque and applied force. In order address challenge simultaneously extrapolating multiple novel extrapolation framework proposed. This utilizes rainflow counting obtain mean amplitude sequences loads. extreme values sequence are fitted using Generalized Pareto Distribution (GPD), while median Double Kernel Density Estimation (DKDE). By Inverse Cumulative Function (ICDF) based on...
Neural stem cell (NSC) transplantation has recently become a main research target for Alzheimer’s disease (AD) treatment. In the present study, we transplanted NSCs from C57BL/6 mice into hippocampus in 12-month-old triple transgenic model of AD (3 × Tg) and determined whether NSC can alleviate impairments spatial learning memory via neuronal regeneration mice. Two months after transplantation, Morris water maze tests suggested that 3 Tg receiving was significantly improved compared to not...
The aim of this work was to explore the applicable value (1)H-MRS evaluation on treatment Alzheimer's disease (AD) with neural stem cell (NSC) transplantation by quantitative analysis metabolite changes in hippocampal area AβPP/PS1 transgenic (tg) mice. tg mice (n = 30) aged 12 months were randomized into two subgroups: One receiving NSCs and other PBS bilateral CA1 region. wild-type 15) used as control group. performed before 6 weeks after measure change N-acetylaspartate (NAA),...
Drug‑induced liver injury has become a serious public health problem. Although the mechanism of acetaminophen (APAP)‑induced been studied for decades it not fully elucidated. In‑depth study into mechanisms underlying APAP‑induced may provide useful information more effective prevention and treatment. In present study, role C‑X‑C motif chemokine ligand‑9 (CXCL9) in was investigated thus providing novel direction treatment drug hepatitis. A total 20 fasting male patients ingested APAP tablets...
Non‑alcoholic fatty liver disease (NAFLD) is the most common in developed countries, which fat accumulation induced by non‑alcoholic factors. The present study was conducted to identify NAFLD‑associated long non‑coding RNAs (lncRNAs), mRNAs and microRNAs (miRNAs). microarray dataset GSE72756, included 5 NAFLD tissues controls, acquired from Gene Expression Omnibus database. Differentially expressed lncRNAs (DE‑lncRNAs) (DE‑mRNAs) were detected using pheatmap package. Using clusterProfiler...
Frailty is associated with perioperative adverse outcomes, especially for the elderly. This study aimed to assess whether frailty was an independent risk factor of one-year mortality in frail patients after elective orthopedic surgery. In this prospective study, three hundred and thirteen aged ≥ 65 years, undergoing surgery were finally included. assessed by Clinical Score (CFS) before present 29.7% (93/313). Among them, 7.7% (24/313) died at one year multivariate logistic analysis, higher...
To investigate the value of hydrogen proton magnet resonance spectroscopy ( 1 H-MRS) in differential diagnosis multiple-domain amnestic mild cognitive impairment (M-aMCI) and vascular with no dementia (VCIND); H-MRS was performed patients M-aMCI VCIND. The level determined for N-acetylaspartate (NAA), glutamate (Glu), inositol (mI), choline (Cho), creatine (Cr). Compared normal control group, NAA–Cr ratio all regions studied significantly lower VCIND groups. Glu–Cr posterior cingulate gyrus...
The load spectrum of rotary drilling rig’s drill pipe is used for design, simulated fatigue testing, and reliability assessment. However, the proper extrapolation double challenging, especially to meet requirements both sequence strengthening. In this paper, an technique a proposed. time rainflow counting proposed keep torque pressure sequence. Meanwhile, individual distributions loads are accurately estimated. Finally, extrapolated by percentile method. results show that method maintaining...