A5077013869- Metal complexes synthesis and properties
- Metal-Organic Frameworks: Synthesis and Applications
- IL-33, ST2, and ILC Pathways
- Atherosclerosis and Cardiovascular Diseases
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Microwave-Assisted Synthesis and Applications
- Retinal Diseases and Treatments
- Advanced Nanomaterials in Catalysis
- Adipokines, Inflammation, and Metabolic Diseases
- Glaucoma and retinal disorders
- Adipose Tissue and Metabolism
- Transportation Safety and Impact Analysis
- Electrochemical sensors and biosensors
- Carbon and Quantum Dots Applications
- Eosinophilic Esophagitis
- Inflammation biomarkers and pathways
- Magnetism in coordination complexes
- Advanced ceramic materials synthesis
- Immune cells in cancer
- Advanced materials and composites
- Advanced biosensing and bioanalysis techniques
- Metabolomics and Mass Spectrometry Studies
- Retinal Imaging and Analysis
- Nuclear Receptors and Signaling
Nanjing Medical University
2020-2025
Henan University of Engineering
2014-2024
Shanghai Industrial Technology Institute
2024
Union Hospital
2016-2023
Huazhong University of Science and Technology
2013-2023
China-Japan Friendship Hospital
2008-2023
Jiangsu Province Hospital
2023
Union Hospital
2023
Chinese University of Hong Kong
2016-2022
First Affiliated Hospital of Hebei Medical University
2018-2021
Inhibition of microRNA-92a (miR-92a) is reported to suppress endothelial inflammation and delay atherogenesis. We hypothesize that miR-92a inhibition protects function through suppressing oxidative stress in diabetic db/db mice.In this study, we found elevated expression aortic endothelium from mice renal arteries subjects. Endothelial cells (ECs) exposed advanced glycation end products (AGEs) oxidized low-density lipoprotein express higher level miR-92a. Overexpression impairs...
BMAL1, the nonredundant transcription factor in core molecular clock, has been implicated cardiometabolic diseases mice and humans. BMAL1 controls cyclic trafficking of Ly6chi monocytes to sites acute inflammation. Myeloid deficiency Bmal1 also worsens chronic inflammation diet-induced obesity. We studied whether myeloid deletion promotes atherosclerosis by enhancing monocyte recruitment atherosclerotic lesions. By generating Bmal1FloxP/FloxP;LysMCre on Apoe-/- background, we showed that...
[Figure: see text].
Three 2-D and 3-D Cu(<sc>ii</sc>), Ni(<sc>ii</sc>), Co(<sc>iii</sc>) complexes were obtained by reaction of <bold>HL1</bold> with different metal salts. The characterized single-crystal X-ray crystallography spectroscopic methods, as well Hirshfeld surface analysis DFT studies.
Hydrogen peroxide (H2O2) and glutathione (GSH) have been reported to be associated with a variety of diseases. Therefore, the accurate rapid determination H2O2 GSH was very important. The traditional assay colorimetric method, which suffered from bottleneck single-mode analysis. In this work, we designed dual-mode fluorescence sensor for detecting based on bifunctional Fe, Co-CDs, possessed peroxidase (POD)-mimetic activity property. Concretely, Co-CDs catalyzed oxidation...
Acylcarnitines are exerting a variety of biological functions depending on the differences in lengths, saturation levels, and conjugation groups, which to great extent contribute challenges acylcarnitines quantifications due various kinds isomers. Here, we describe novel method by using high-resolution parallel reaction monitoring (PRM) liquid chromatography-tandem mass spectrometry (LC-MS/MS). Both reversed-phase normal-phase column were used order get accurate, reliable, widespread...
Objectives To investigate the effect of metformin on decreased risk developing age-related macular degeneration (AMD) in patients with type 2 diabetes mellitus (T2DM) for ≥10 years. Design A retrospective study. Participants Patients aged ≥50 a diagnosis T2DM no less than 10 years were included. Methods Variables predisposing to AMD reviewed; potential confounders related or selected from literature records; and diabetic retinopathy (DR) diagnosed by funduscopy, optical coherence tomography...
Vaccines offer prophylactic treatments against atherosclerosis by eliciting effector T cell and antibody responses, which require effective delivery of antigen adjuvant to activate dendritic cells (DC). Here we show that individual conjugation p210 CpG oligodeoxynucleotides onto superparamagnetic iron oxide nanoparticles formulates a nanovaccine cocktail activates DCs for cross-presentation induction co-stimulatory signals, cytokines CD8+ effector/effector memory responses. This modulates...
Two two‐dimensional supramolecular copper(II) and cobalt(III) complexes, Cu(L 1 ) 2 ( ; HL = 2‐hydroxy‐3‐methoxybenzaldehyde oxime) [Co(L ] ⋅2CH 3 COOCH CH 1‐(2‐{[( E )‐3‐methoxy‐2‐hydroxybenzylidene]amino}phenyl)ethanone oxime), have been synthesized via complexation of Cu(II) nitrate trihydrate Co(II) acetate tetrahydrate with HL. A plausible reaction mechanism for the formation is proposed. was characterized using infrared, H NMR 13 C spectra, as well elemental analysis. Complexes were...
Two two‐dimensional supramolecular Nickel(II) and Cobalt(III) complexes, [Ni( L 2 ) ]·2CH 3 OH ( 1 [2Co( ] HL = 1‐(2‐{[( E )‐3‐bromo‐5‐chloro‐2‐hydroxybenzylidene]amino}phenyl)ethanone oxime), were synthesized via complexation of salts acetate with (2‐(3‐bromo‐5‐chloro‐2‐hydroxyphenyl)‐4‐methyl‐1,2‐dihydroquinazoline 3‐oxide, H is the deprotonatable hydrogen). During reaction, C–N bond in converted into C=N–OH group . The spectroscopic data both complexes compared ligand determined by...
Cashmere and wool fibers have similar chemical compositions, making them difficult to distinguish based on their absorption peaks band positions in near-infrared spectroscopy. Existing studies commonly use wavelength selection or feature extraction algorithms obtain significant spectral features, but traditional often overlook the correlations between wavelengths, resulting weak adaptability local optimum issues. To address this problem, paper proposes a recognition algorithm optimal...