A5056710341- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Bladder and Urothelial Cancer Treatments
- Sexual Differentiation and Disorders
- Ureteral procedures and complications
- Urinary Bladder and Prostate Research
- Urologic and reproductive health conditions
- Tissue Engineering and Regenerative Medicine
- Pelvic floor disorders treatments
- Congenital gastrointestinal and neural anomalies
- Urinary and Genital Oncology Studies
- Spinal Dysraphism and Malformations
- Genital Health and Disease
- Diverticular Disease and Complications
- Urinary Tract Infections Management
- Kidney Stones and Urolithiasis Treatments
- Hernia repair and management
- Testicular diseases and treatments
- Intestinal Malrotation and Obstruction Disorders
- Cerebrospinal fluid and hydrocephalus
- Congenital Anomalies and Fetal Surgery
- Renal and related cancers
- Sexual function and dysfunction studies
- Electrospun Nanofibers in Biomedical Applications
- Childhood Cancer Survivors' Quality of Life
Riley Hospital for Children
2016-2025
Indiana University – Purdue University Indianapolis
2015-2025
Indiana University Health
2016-2025
Indiana University School of Medicine
2014-2024
Indiana University
1997-2021
University School
2021
Indianapolis Zoo
2010-2020
University of Minnesota Rochester
2020
Columbus Oncology and Hematology Associates
2020
Hôpital Lapeyronie
2016
No AccessJournal of UrologyInvestigative Urology1 Jun 1996Regenerative Urinary Bladder Augmentation Using Small Intestinal Submucosa: Urodynamic and Histopathologic Assessment in Long-term Canine augmentations Bradley P. Kropp, Marian K. Rippy, Stephen F. Badylak, Mark C. Adams, Michael A. Keating, Richard Rink, Karl B. Thor KroppBradley Kropp More articles by this author , RippyMarian Rippy BadylakStephen Badylak AdamsMark Adams KeatingMichael Keating RinkRichard Rink ThorKarl View All...
No AccessJournal of Urology1 Nov 1988Gastrocystoplasty: An Alternative Solution to the Problem Urological Reconstruction in Severely Compromised Patient Mark C. Adams, Michael E. Mitchell, and Richard Rink AdamsMark Adams More articles by this author , MitchellMichael Mitchell RinkRichard View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)41986-0AboutPDF ToolsAdd favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail isolated segment...
No AccessJournal of UrologyOncology1 Oct 2004TRANSITIONAL CELL CARCINOMA OF THE BLADDER FOLLOWING AUGMENTATION CYSTOPLASTY FOR NEUROPATHIC TREVOR M. SOERGEL, MARK P. CAIN, ROSALIA MISSERI, THOMAS A. GARDNER, MICHAEL O. KOCH, and RICHARD C. RINK SOERGELTREVOR SOERGEL , CAINMARK CAIN MISSERIROSALIA MISSERI GARDNERTHOMAS GARDNER KOCHMICHAEL KOCH RINKRICHARD View All Author Informationhttps://doi.org/10.1097/01.ju.0000140194.87974.56AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...
We characterized small intestinal submucosa regenerated canine bladder.We subjected 15-month bladder strips to in vitro muscle bath compliance, contractility testing and immunohistochemical staining.Compliance studies demonstrated no significant difference between control bladders, which were 30-fold more compliant than native submucosal graft material. Contractility contractile responses innervation similar those of normal bladder. Afferent nerves through techniques.These characteristics...
Obstruction of the upper urinary tract induces a progressive loss in renal mass through apoptotic cell death. Although TNF-alpha has been implicated ischemia-reperfusion-induced death, its role obstructive apoptosis remains unknown. To study this, male Sprague-Dawley rats were subjected to left unilateral ureteral obstruction vs. sham operation. Twenty-four hours before surgery and every 84 h thereafter, received either vehicle or pegylated form soluble TNF receptor type 1 (PEG-sTNFR1). The...
Bladder augmentation has revolutionized the care of children with a neuropathic bladder but it remains major surgical procedure. However, need for subsequent surgery not been well defined in large series long-term followup.We retrospectively reviewed records first 500 augmentations performed from 1978 to 2003 at our institution. Charts were complications requiring additional surgery, including malignancy, perforation, repeat augmentation, bowel obstruction and calculi. Mean median followup...
No AccessJournal of UrologyPEDIATRIC UROLOGY1 Nov 1999APPENDICOVESICOSTOMY AND NEWER ALTERNATIVES FOR THE MITROFANOFF PROCEDURE: RESULTS IN LAST 100 PATIENTS AT RILEY CHILDREN′S HOSPITAL MARK P. CAIN, ANTHONY J. CASALE, SHELLY KING, and RICHARD C. RINK CAINMARK CAIN , CASALEANTHONY CASALE KINGSHELLY KING RINKRICHARD View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)68230-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
Occult lesions of the spine in children are a rare but recognizable cause neurogenic dysfunction involving lower extremities, and urinary gastrointestinal tracts. We report preoperative postoperative urodynamic findings 40 with varying spinal abnormalities. Of these patients 28 were neonates or infants (average age 8.7 months) 12 older 11.7 years). Preoperative testing revealed normal function 18 (64 per cent) younger group contrast to 1 (8 group. 10 abnormal studies returned 6, while 2...
The spontaneous perforation of an augmented bladder is uncommon but serious complication. To our knowledge institution has the largest reported series augmentations. We examined data to determine incidence and delineate associated risk factors.We performed a retrospective chart review 500 augmentation procedures during preceding 25 years with minimum followup 2 years.Spontaneous perforations occurred in 43 patients (8.6%), for total 54 events. calculated was 0.0066 per augmentation-year at...
We previously reported that the self-reported amount of urinary incontinence is main predictor lower health related quality life in adults with spina bifida. In this study we sought to determine impact fecal on after correcting for incontinence.An international sample bifida was surveyed online 2013 2014. evaluated last 4 weeks using clean intervals (less than 1 day, 6 days, week or longer, no incontinence), (a lot, medium, a little none), number protective undergarments worn daily and...
Inadequate bladder emptying is a common urinary dysfunction in children. The role of alpha-blockers for managing outlet obstruction remains relatively unexplored Because the well established impact alpha-blocker therapy men, we investigated its use treating inadequate pediatric population.We treated 17 children 3 to 15 years old with documented poor various etiologies, including dysfunctional voiding, Hinman syndrome, lazy posterior urethral valves, myelomeningocele and prune-belly using...
Ischemia causes renal tubular cell loss through apoptosis; however, the mechanisms of this process remain unclear. Using epithelial line LLC-PK 1 , we developed a model simulated ischemia (SI) to investigate role p38 MAPK (mitogen-activated protein kinase) in tumor necrosis factor-α (TNF-α) mRNA production, bioactivity, and apoptosis. Results demonstrate that 60 min SI induced maximal TNF-α production bioactivity. Furthermore, apoptosis at all substrate replacement time points examined, with...
Rather than resecting the distal spongiosum lateral to open urethra for hypospadias, we mobilized this tissue with urethral plate away from corpora cavernosa, subsequently wrapping it around various types of urethroplasty prevent fistula formation.The was preserved and used coverage in 25 hypospadias repairs 1 year. We initially applied manner when persisted as a pillar healthy erectile but later appeared more fibrous nature. The wrap cover urethroplasty, including advancement 6 cases,...
Bladder augmentation is now a commonly accepted treatment in children with neuropathic bladder and other anomalies. calculi have been reported third to half of pediatric patients after augmentation. We identify the incidence risk factors for stone formation large series augmentation.We reviewed records 286 who underwent between 1978 1994, assessed calculi, methods.Bladder developed 29 (10%) The type bowel used did not affect rate except stomach, which lead any case. Stones formed more outlet...
No AccessJournal of UrologyGenitalia1 Oct 2005MANAGEMENT OF PERINATAL TORSION: TODAY, TOMORROW OR NEVER? ELIZABETH B. YERKES, FRANK M. ROBERTSON, JORDAN GITLIN, MARTIN KAEFER, MARK P. CAIN, and RICHARD C. RINK YERKESELIZABETH YERKES , ROBERTSONFRANK ROBERTSON GITLINJORDAN GITLIN KAEFERMARTIN KAEFER CAINMARK CAIN RINKRICHARD View All Author Informationhttps://doi.org/10.1097/01.ju.0000179542.05953.11AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
We report the long-term outcome of Malone antegrade continence enema procedure in treatment chronic constipation and fecal incontinence children with neuropathic bowel.We performed a retrospective chart review 256 procedures. Patient age at surgery, bowel segment used, location stoma, number type revisions required, were documented database was created.A total 236 patients least 6 months followup are included this report. There 172 situ appendicocecostomies, 23 split appendix channels, 9...
Patients with rare and complex diseases such as congenital adrenal hyperplasia (CAH) often receive fragmented inadequate care unless efforts are coordinated among providers. Translating the concepts of medical home comprehensive health for individuals CAH offers many benefits affected their families. This manuscript represents recommendations a 1.5 day meeting held in September 2009 to discuss ideal goals centers newborns, infants, children, adolescents, adults CAH. Participants included...