- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Digital Imaging for Blood Diseases
- Multimodal Machine Learning Applications
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Visual Impairment Studies
- Domain Adaptation and Few-Shot Learning
- Organic Light-Emitting Diodes Research
- Organic Electronics and Photovoltaics
- Erythropoietin and Anemia Treatment
- Intraocular Surgery and Lenses
- 3D IC and TSV technologies
- Corneal surgery and disorders
- Ophthalmology and Eye Disorders
- Millimeter-Wave Propagation and Modeling
- Plant-Microbe Interactions and Immunity
- Cerebral Venous Sinus Thrombosis
- IPv6, Mobility, Handover, Networks, Security
- Advanced Antenna and Metasurface Technologies
- Blood transfusion and management
- Image Retrieval and Classification Techniques
- Chromatin Remodeling and Cancer
- Electronic Packaging and Soldering Technologies
National Taiwan University Hospital
2025
National Taiwan Ocean University
2021-2024
Taichung Veterans General Hospital
2023
Taipei Medical University Hospital
2022-2023
National Taiwan University
2017-2023
National Chiayi University
2023
Taipei Institute of Pathology
2023
Tri-Service General Hospital
2018-2022
National Defense Medical Center
2019-2022
Keelung Chang Gung Memorial Hospital
2021
In this work, we propose an AI-based method that intends to improve the conventional retinal disease treatment procedure and help ophthalmologists increase diagnosis efficiency accuracy. The proposed is composed of a deep neural networks-based (DNN-based) module, including identifier clinical description generator, DNN visual explanation module. To train validate effectiveness our DNN-based large-scale image dataset. Also, as ground truth, provide dataset manually labeled by qualitatively...
Abstract Background Anaemia is highly prevalent in critically ill patients; however, the long-term effect on mortality remains unclear. Methods We retrospectively included patients admitted to medical intensive care units (ICUs) during 2015–2020 at Taichung Veterans General Hospital. The primary outcome of interest was one-year mortality, and hazard ratios (HRs) with 95% confidence intervals (CIs) were determined assess association. used propensity score matching (PSM) methods, including...
Rhizobacteria from various ecological niches display variations in physiological characteristics. This study investigates the transcriptome profiling of two Bacillus subtilis strains, BsCP1 and BsPG1, each isolated distinct environments. Gene expression linked to synthesis seven types antibiotic compounds was detected both BsPG1 cultures. Among these, genes associated with plipastatin were predominantly expressed bacterial strains. However, responsible for polyketide, subtilosin, surfactin...
Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access specialists. We propose novel visual-assisted hybrid model based on the support vector machine (SVM) and deep neural networks (DNNs). The incorporates complementary strengths DNNs SVM. Furthermore, we present new retina label collection for ophthalmology incorporating 32 classes. Using EyeNet, our achieves 89.73% accuracy performance is comparable...
Three new carbazole-based materials were designed for exciplex formation with PO-T2T. Then, the selected cohost two D–A–D-configurated fluorescent emitters, <bold>iCzPNT</bold> and <bold>iCzBTh2CN</bold>, to produce high efficiency OLEDs.
Small cell carcinoma is predominantly found in the lung and only about 5% of small cases have been noted to be extrapulmonary; these are commonly esophagus, pancreas, skin, uterus, breast. A head neck origin for extremely rare. Both pulmonary extrapulmonary carcinomas usually a good response chemotherapy initially, but poor prognosis finally. We report here case nasopharynx. The patient underwent irradiation disease, died metastasis 38 months later.
Automatically generating medical reports from retinal images is a difficult task in which an algorithm must generate semantically coherent descriptions for given image. Existing methods mainly rely on the input image to descriptions. However, many abstract concepts or cannot be generated based information only. In this work, we integrate additional help solve task; observe that early diagnosis process, ophthalmologists have usually written down small set of keywords denoting important...
With the rapid development of wireless communication, mobile users are able to manually switch their network interfaces different types networks. The IEEE 802.21 Draft Standard was proposed integrate Media Independent Handover (MIHs) between interfaces, such as WiFi, WiMAX, 3GPP, and 3GPP2. However, it may not hold seamless roaming character does provide security mechanism.In this paper, we propose an efficient handover mechanism among WiFi WiMAX networks meet by reducing authentication...
Purpose Optic neuritis is highly correlated with multiple sclerosis and a major cause of acute visual loss long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion changed patients optic (AON). Methods three-year cohort was conducted from September 1 2012, to August 31, 2015. Two hundred forty-one non-glaucomatous neuropathy were screened, 42 non-highly myopic who had suffered...
To report the clinical course and treatment response in a cohort of patients with neuromyelitis optica spectrum disorder (NMOSD) from single referral center Taiwan.
We conducted a retrospective group study to evaluate the potential systemic risk factors for major postoperative complications of cataract surgery. Individuals diagnosed with (n = 2046) and without 8184) serious after surgery were matched 1:4 age, sex, index date obtained using Taiwan's National Health Insurance Research Database. The outcome was defined as at least one new inpatient or outpatient diagnosis disease year before date. effect demographic data on also analyzed in multivariable...
To report a rare case of severe atypical hemolytic-uremic syndrome (HUS) in patient who presented with vitreous hemorrhage and tractional retinal detachment (TRD) both eyes. our knowledge, this is the first reported HUS complicated bilateral TRD literature.A 20-year-old man demonstrated visual acuity hand motion at 30 cm.Dilated fundus examination revealed diffuse intraretinal vascular engorgement, neovascularization disc, elsewhere bilaterally. Fluorescein angiography proliferative...
The aim of this study was to investigate whether exogenous erythropoietin (EPO) administration attenuates N-methyl-D-aspartate (NMDA)-mediated excitotoxic retinal damage in Wistar rats. survival rate ganglion cells (RGCs) were investigated by flat mount analysis and flow cytometry. A total 125 male rats randomly assigned five groups: negative control, NMDA80 (i.e., 80 nmoles NMDA intravitreally injected), + 10ng EPO, 50ng 250ng EPO. EPO treatment group used evaluate various administrated...
This paper first presents the architecture of a self-designed, slot-coupled patch antenna unit in glass-embedded fan-out package. Due to embedded glass, design flexible and radiation properties structure was improved by single or double-sided made redistribution layers (RDLs) on glass surfaces. The FOAiP is an extended application technology advanced electronics It provides ideal approach for millimeter-wave (mmWave) chip with low transmission loss chip-to-antenna interconnect greater...
This study compared the metabolites in brain regions of hippocampus and corpus callosum between patients with mild cognitive impairment (MCI) healthy controls using no-radiation high-sensitivity magnetic resonance spectroscopy (MRS) three-dimensional chemical shift images (3D-CSI). Twenty volunteers (seven MCI 13 controls) aged 50–71 years were recruited for this prospective study. MRS 3D-CSI a variety was collected from callosum. Sex weight showed no significant differences two groups. The...
The efficacy of combined intravitreal bevacizumab injection with systemic chemotherapy, palliative radiotherapy, and hormonal therapy to treat choroidal orbital metastases is not known. Herein, we report the case a 48-year-old woman chemotherapy-resistant left eye originating from stage IV invasive ductal carcinoma breast. We describe addition single in treatment therapy, radiotherapy. patient’s outcome at 6-month follow-up was favorable, as metastatic lesion reduced size visual acuity...
Abstract Two 2,7-dicyaonfluorene-based molecules 27-DCN and 27 - tDCN are utilized as acceptors (A) to combine with hexaphenylbenzene-centered donors (D) TATT DDT-HPB for probing the exciplex formation. The photophysical characteristics reveal that steric hindered -tDCN not only can increase distance of D A, resulting in a hypsochromic emission, but also dilute concentration triplet excitons suppress non-radiative process. -based exciplex-forming blends exhibit better photoluminescence...
<title>Abstract</title> Background Laser-assisted in situ keratomileusis (LASIK) is widely used to correct refractive errors myopia and astigmatism. The choice of presbyopia-correcting intraocular lenses (IOLs) for post-LASIK cataract surgery a significant concern. However, few direct comparison studies exist between eyes with without history LASIK. We analyzed the performance extended depth focus (EDOF) IOL implantation these two groups. Methods This retrospective single-center study...
We evaluated the clinical utility of ultra-widefield imaging as an adjunctive tool for training resident ophthalmologists in detection retinal breaks. This was a prospective study conducted at secondary health care center (Tri-Service General Hospital) Taiwan. Participants were 44 patients (53 eyes) who referred to our hospital after being diagnosed with Patients first underwent indirect ophthalmoscopy examination total fundus without scleral depression by junior (first and second year) or...
Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access specialists. Based on the fact that fundus structure and vascular disorders are main characteristics diseases, we propose novel visual-assisted hybrid model mixing support vector machine (SVM) deep neural networks (DNNs). Furthermore, present new retina dataset, called EyeNet2, for ophthalmology incorporating 52 classes. Using our achieves 90.43\%...
With the advancement of deep learning in many computer vision applications, computer-aided diagnosis (CAD) systems were developed using approaches to assist physicians clinical as a second opinion. Many studies have reported plausible performance models on glaucoma detection simply based fundus images. However, mechanism detecting color is still not clear. Therefore, features extracted by discussed this study provide visual interpretability for frameworks convolutional neural network (DCNN)...