A5072009798- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Hepatitis C virus research
- Economic and Financial Impacts of Cancer
- Pregnancy and Medication Impact
- Multiple and Secondary Primary Cancers
- Childhood Cancer Survivors' Quality of Life
- Tuberous Sclerosis Complex Research
- Cancer Research and Treatments
- Ferroptosis and cancer prognosis
- Hops Chemistry and Applications
- Family Support in Illness
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Pancreatic function and diabetes
- Neurotransmitter Receptor Influence on Behavior
- Alcohol Consumption and Health Effects
- Genetic factors in colorectal cancer
- Cancer survivorship and care
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Breastfeeding Practices and Influences
- Cannabis and Cannabinoid Research
The University of Texas Southwestern Medical Center
2022-2024
Southwestern Medical Center
2022-2024
Parkland Health & Hospital System
2024
American University of Beirut
2021-2022
Importance Cohort studies demonstrating an association of hepatocellular carcinoma (HCC) screening with reduced mortality are prone to lead-time and length-time biases. Objective To characterize the clinical benefits HCC screening, adjusting for biases, in a diverse, contemporary cohort at-risk patients. Design, Setting, Participants This retrospective study patients was conducted between January 2008 December 2022 at 2 large US health systems. Data analysis performed from September November...
Background Hepatocellular carcinoma (HCC) is plagued by failures across the cancer care continuum, leading to frequent late-stage diagnoses and high mortality. We evaluated effectiveness of mailed outreach invitations plus patient navigation promote HCC screening process completion in patients with cirrhosis. Methods Between April 2018 September 2021, we conducted a multicentre pragmatic randomised clinical trial comparing for (n=1436) versus usual visit-based among cirrhosis at three US...
Hepatocellular carcinoma (HCC) surveillance is associated with improved early tumor detection, but effectiveness limited by underuse. We characterized adherence to HCC using proportion of time covered (PTC) and estimated its association clinical outcomes among patients cirrhosis.
Background: Growing evidence suggests that liver disease originates in early life. Antihistamines cross the placenta and are frequently prescribed to pregnant women treat nausea vomiting, as well allergy asthma symptoms. Exposure antihistamines utero may impact developing by reprogramming or inducing epigenetic changes fetal hepatocytes. Methods: We examined exposure risk of HCC Child Health Development Studies, a multigenerational cohort enrolled East Bay, CA, between 1959 1966 (n=14,507...
Abstract Background The value of hepatocellular carcinoma screening is defined by the balance benefits from early tumor detection vs harms because false-positive results. We evaluated a mailed outreach strategy for in patients with cirrhosis. Methods conducted multicenter pragmatic randomized clinical trial comparing (n = 1436) and usual care visit-based among cirrhosis at 3 health systems March 2018 to September 2021. Outcomes interest were stage (ie, benefit) diagnostic evaluation or...
Racial and ethnic disparities have been reported for HCC prognosis, although few studies fully account clinically important factors social determinants of health, including neighborhood socioeconomic status.
Patients with hepatocellular cancer (HCC) are vulnerable to psychological distress given a new diagnosis superimposed on pre-existing chronic liver disease. We aimed characterise the psychiatric burden in HCC, risk factors for incident and treatment patterns over time.
Cannabis is the most widely trafficked and abused illicit drug due to its calming psychoactive properties. It has been increasingly recognized as having potential health benefits relatively less adverse effects compared other drugs; however, growing evidence clearly indicates that cannabis associated with considerable cardiovascular events. Recent studies have linked use myocardial infarction (MI); yet, very little known about underlying mechanisms. A MI a disease characterized by mismatch...