A5067842907- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiology practices and education
- Pancreatic and Hepatic Oncology Research
- Advanced Radiotherapy Techniques
- Liver Disease and Transplantation
- Radiation Dose and Imaging
- Advances in Oncology and Radiotherapy
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Ultrasound in Clinical Applications
- Gallbladder and Bile Duct Disorders
- Renal cell carcinoma treatment
- Surgical Simulation and Training
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Ultrasound and Hyperthermia Applications
- Cancer, Hypoxia, and Metabolism
- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- COVID-19 and healthcare impacts
- Healthcare Quality and Management
Michigan Medicine
2017-2025
University of Michigan
2016-2025
Klinikum Braunschweig
2024
University Hospital Magdeburg
2024
University of Kansas Medical Center
2024
Baptist Hospital of Miami
2024
Ann Arbor Center for Independent Living
2024
Duke Medical Center
2021-2024
Cornell University
2024
Mayo Clinic
2022
Singal, Amit G.; Llovet, Josep M.; Yarchoan, Mark; Mehta, Neil; Heimbach, Julie K.; Dawson, Laura A.; Jou, Janice H.; Kulik, Agopian, Vatche Marrero, Jorge Mendiratta-Lala, Mishal; Brown, Daniel B.; Rilling, William S.; Goyal, Lipika; Wei, Alice C.; Taddei, Tamar H. Author Information
Background Abbreviated MRI is a proposed paradigm shift for hepatocellular carcinoma (HCC) surveillance, but data on its performance are lacking histopathologically confirmed early-stage HCC. Purpose To evaluate the sensitivity and specificity of dynamic contrast-enhanced abbreviated HCC detection, using surgical pathologic findings as reference standard. Materials Methods This retrospective study was conducted at three U.S. liver transplant centers in patients with cirrhosis who underwent...
Background and Aims There are limited data on hepatocellular carcinoma (HCC) growth patterns, particularly in Western cohorts, despite implications for surveillance, prognosis, treatment. Our study’s aim was to quantify tumor doubling time (TDT) identify correlates associated with indolent rapid growth. Approach Results We performed a retrospective multicenter cohort study of patients cirrhosis diagnosed HCC from 2008 2017 at six US European health systems two or more contrast‐enhanced...
Background Histotripsy is a nonthermal, nonionizing, noninvasive, focused US technique that relies on cavitation for mechanical tissue breakdown at the focal point. Preclinical data have shown its safety and technical success in ablation of liver tumors. Purpose To evaluate histotripsy destroying primary or metastatic Materials Methods The parallel United States European Union England #HOPE4LIVER trials were prospective, multicenter, single-arm studies. Eligible patients recruited 14 sites...
Focal liver lesions (FLLs) have become an increasingly common finding on abdominal imaging, especially asymptomatic and incidental lesions. Gastroenterologists hepatologists often see these patients in consultation make recommendations for management of multiple types lesions, including hepatocellular adenoma, focal nodular hyperplasia, hemangioma, hepatic cystic polycystic disease. Malignancy is important to consider the differential diagnosis FLLs, healthcare providers must be familiar...
Histotripsy has been used for tumor ablation, through controlled, non-invasive acoustic cavitation. This is the first study to evaluate impact of partial histotripsy ablation on immune infiltration, survival outcomes, and metastasis development, in an vivo orthotopic, immunocompetent rat HCC model (McA-RH7777). At 7–9 days post-tumor inoculation, grew 5–10 mm, ~50–75% volume was treated by ultrasound-guided histotripsy, delivering 1–2 cycle pulses at 100 Hz PRF (focal peak negative pressure...
Patterns of Fat StrandingEavan Thornton1, Mishal Mendiratta-Lala1, Bettina Siewert1 and Ronald L. Eisenberg1Audio Available | Share
To evaluate the use of radiofrequency (RF) ablation as a primary treatment for symptomatic functional adrenal neoplasms and determine efficacy with clinical biochemical follow-up.After obtaining institutional review board approval, authors retrospectively evaluated images medical records from 13 consecutive patients (<3.2 cm in diameter) who underwent RF during 7-year period. There were six men seven women mean age 54.1 years (range, 42-71 years). Cross-sectional images, findings...