A5016095881- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Nuclear Physics and Applications
- Graphite, nuclear technology, radiation studies
- Radiation Detection and Scintillator Technologies
- Nuclear and radioactivity studies
- Dark Matter and Cosmic Phenomena
- Enzyme Structure and Function
- Nuclear reactor physics and engineering
- Radiation Therapy and Dosimetry
- Protein Structure and Dynamics
- Radiation Shielding Materials Analysis
- Photonic and Optical Devices
- Photorefractive and Nonlinear Optics
- Enzyme Production and Characterization
- Radiation Dose and Imaging
- Cosmology and Gravitation Theories
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Radiotherapy Techniques
- Radioactive contamination and transfer
- Nonlinear Waves and Solitons
- Semiconductor Lasers and Optical Devices
- Nonlinear Photonic Systems
Kagoshima University
1984-2024
Kyoto Prefectural University
2013-2024
Ritsumeikan University
2012-2024
Asahi Kasei (Japan)
2024
Teikyo University
2024
Child Guidance Center
2024
Kanazawa Medical Center
2008-2023
Japan Space Forum
2011-2021
University of Yamanashi
2020-2021
Railway Technical Research Institute
2020
A geometric-progression (G-P) method formula, Br = 1 + (B − 1) · (Kx 1)/(K 1), accurately represents the buildup factor data as a function of distance for following reasons:1. The value parameter B corresponds to that at mfp, which is integration basic spectrum specified material and source energy.2. variation K with penetration photon dose multiplication change in shape spectrum.Exposure factors point isotropic sources an infinite medium approximated by G-P fitting parameters are good...
A novel protein with mitogenic activity in vitro and immunomodulating vivo has been isolated from the mycelial extract of an Oriental medicinal fungus, Ling Zhi (Ganoderma lucidium). This was named Zhi-8 (LZ-8) its biochemical immunological properties are described. LZ-8 purified by two chromatographic systems, gel filtration followed ion-exchange, using bioassay measuring blast-formation stimulatory toward mouse spleen lymphocytes to monitor purification. Analysis several types...
A review of the recent works on periodic multi-soliton solutions KdV equation is given. Connection with theory abelian integrals emphasized. Discrete analogue also discussed leading to exact Toda lattice.
Abstract —Angiotensin II (Ang II) is now believed to play a critical role in the pathogenesis of hypertrophy and/or hyperplasia vascular smooth muscle cells (VSMCs). Several G i - and q -coupled receptors, including Ang type 1 (AT ) receptor, activate Rho Rho-associated kinase Swiss 3T3 cardiac myocytes. However, little known about Rho-kinase II–induced VSMCs. In present study, we explored protein synthesis unstimulated cells, RhoA was observed predominantly cytosolic fraction, but it...
An analogue of the inverse scattering theory for discrete Hill's equation is developed. A method consists introduction abelian integrals and solution Jacobi's inversion problem. The motion periodic Tod lattice integrated exactly by means Riemann theta functions.
Aim:We previously reported that glycemic control deteriorated in patients receiving atorvastatin, which is useful for the treatment of hypercholesterolemia with type 2 diabetes.Pitavastatin has a strong lipid-lowering effect, comparable to but it unknown whether pitavastatin an adverse influence on control.The aim this study was examine.The effects three different statins (pravastatin, and pitavastatin) blood glucose HbA1c levels diabetic patients.Methods: We retrospectively compared between...
8-Anilino-1-naphthalenesulfonic acid (ANS) is used as a hydrophobic fluorescence probe due to its high intensity in environments, and also microenvironment because of unique ability exhibit peak shift change depending on the surrounding solvent environment. The difference can not only be caused by but affected binding affinity, which represented constant (K). However, overall process considering fully understood, requires ANS mechanism examined. In this study, reveal rate-limiting step...
Reactive oxygen species (ROS) have been proposed to mediate vascular hypertrophy induced by angiotensin II (Ang II). Recently, we and others shown that growth-promoting signals Ang involve protein tyrosine kinase (PTK) extracellular signal-regulated (ERK). However, whether ROS contribute the II-induced PTK and/or ERK activation in smooth muscle cells (VSMCs) remains largely unclear. Here, investigated possible involvement of activation. In presence a NADH/NADPH oxidase inhibitor,...
Abstract Dehydroepiandrosterone (DHEA) and its sulfate ester are the most abundant circulating adrenal steroids in humans. Administration of DHEA has been reported to have beneficial effects on obesity, hyperlipidemia, diabetes, atherosclerosis obese rodents, although insulin resistance not fully elucidated. In this study, treatment sensitivity were investigated genetically Zucker rats, an animal model resistance, using euglycemic clamp technique. After 0.4% was administered for 10 days...
Liposomes have been widely used to enhance the immune response. In present investigation, we studied their in vivo immunomodulation of an HIV-1-specific DNA vaccine candidate (pCMV160/REV) constructed with cytomegalovirus (CMV) promoter-conjugated HIV-1 env and rev plasmids. By immunizing pCMV160/REV cationic liposomes through various routes (intramuscular, intraperitoneal, subcutaneous, intradermal, intranasal), induced higher levels both antibody production delayed-type hypersensitivity...
a fungus, Ganoderma lucidium (Kino, K.,
DNA vaccines have the potential of giving rise to a potent cell-mediated immune response by inducing intracellular synthesis and subsequent antigenic presentation encoded antigens. We tested vaccine specific for human immunodeficiency virus type 1 (HIV-1) injection animals with expression plasmids encoding HIV-1 envelope protein Rev regulatory protein. Injection both into mice, rabbits, or macaques was found induce high levels antibodies capable efficiently inhibiting infection...
We have obtained a complete set of 20 variants the alpha subunit tryptophan synthase Escherichia coli at position 49 in order to extend our previous studies on effects single amino acid replacements structure and function. Thirteen mutant subunits been newly constructed by site-directed mutagenesis using oligonucleotides. Six mutants were available from studies. find that wild type all form 2 beta complexes with similar association constants similarly stimulate activity synthesis...
Lenses made of Bragg-type gratings and used for integrated optics are fabricated by the technique electron-beam pattern generation, chemical etching, printing. They consist straight lines varying inclination spacing. Focusing action is demonstrated experimentally.
FtsZ polymerizes into protofilaments to form the Z-ring that acts as a scaffold for accessory proteins during cell division. Structures of have been previously solved, but detailed mechanistic insights are lacking. Here, we determine cryoEM structure single protofilament from Klebsiella pneumoniae (KpFtsZ) in polymerization-preferred conformation. We also develop monobody (Mb) binds KpFtsZ and Escherichia coli without affecting their GTPase activity. Crystal structures FtsZ-Mb complexes...