A5044411658- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Herpesvirus Infections and Treatments
- Ocular Infections and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Virus-based gene therapy research
- Diabetes Treatment and Management
- Ocular Oncology and Treatments
- Diabetes Management and Research
- Nasolacrimal Duct Obstruction Treatments
- Ophthalmology and Eye Disorders
- Lipoproteins and Cardiovascular Health
- Ophthalmology and Visual Impairment Studies
- Allergic Rhinitis and Sensitization
- Pancreatic function and diabetes
Yokohama City University Medical Center
2016-2025
Yokohama City University
2016-2025
Chinese University of Hong Kong
2022-2023
Hong Kong Eye Hospital
2022-2023
Hodogaya Chemical (Japan)
2015
The University of Tokyo
2006-2012
Tokyo Metropolitan Geriatric Hospital
2011
May Institute
2009
Removal of internal limiting membranes (ILMs) is a potentially useful surgical approach to close an idiopathic macular hole. However, the removal ILMs difficult perform because poor visibility ILMs. We have developed technique for staining ILM with solution indocyanine green facilitate in eyes Thirteen 13 patients (8 women and 5 men, aged from 54 68 years) idiopathical hole stage 3 or 4 that underwent using this had anatomical closure rate 92% improvement visual acuity 89% (>/=2 Snellen...
To evaluate the macular structure on spectral-domain optical coherence tomographic (SD-OCT) images to predict outcome of surgery for idiopathic epiretinal membrane.Forty-five eyes 45 consecutive patients with membrane who had a preoperative visual acuity ≤ 20/32 and were scheduled undergo transconjunctival 25-gauge vitrectomy involved in this prospective cohort study. The best-corrected (BCVA) SD-OCT fovea examined before at 3, 6, 12 months after surgery. Associations between parameters...
Recently, indocyanine green (ICG) has been used to visualize the internal limiting membrane during vitrectomy. After intraocular administration, ICG accumulates at optic disc. In this study, effects of on retinal ganglion cells (RGCs) were examined.In vitro, rat RGCs purified by a two-step immunopanning procedure, briefly exposed (2.5 x 10(3) mg/L), and irradiated with an endoilluminator for 15 minutes or incubated in presence (concentration: 2-250 mg/L) without irradiation. The number...
Aim:We previously reported that glycemic control deteriorated in patients receiving atorvastatin, which is useful for the treatment of hypercholesterolemia with type 2 diabetes.Pitavastatin has a strong lipid-lowering effect, comparable to but it unknown whether pitavastatin an adverse influence on control.The aim this study was examine.The effects three different statins (pravastatin, and pitavastatin) blood glucose HbA1c levels diabetic patients.Methods: We retrospectively compared between...
Abstract This case-control study reports the association between nutrient intake and neovascular age-related macular degeneration (AMD) in Japan. The of 161 AMD cases from two university hospitals 369 population-based control subjects a cohort was assessed using brief-type self-administered questionnaire on diet history, which required respondent recall usual 58 foods during preceding month. Energy-adjusted values were compared groups. Logistic regression analysis used to estimate odds...
Excessively short and long sleep durations are associated with type 2 diabetes, but there is limited information about the association between quality diabetes. Accordingly, present study was performed to investigate this relationship.The subjects were 3249 patients diabetes aged 20 years or older. Sleep assessed by using Pittsburgh Quality Index (PSQI). A higher global PSQI score indicates worse quality, a >5 differentiates poor sleepers from good sleepers.The mean 5.94 ± 3.33, 47.6% of had...
In Brief Purpose: To examine the effects of perfluorocarbon liquid (PFCL) and silicone oil (SO) on human retinal pigment epithelium (RPE) cells ganglion (RGCs) in vitro. Methods: Human RPE (ARPE-19 cells), seeded microporous inserts, were exposed to PFCL or SO incubated for 3 7 days. Perfluorocarbon was contact with at apical baso-lateral side, not inhibiting cell feeding. Then, quantification proliferation viability evaluated by WST-1 assay. same way, RGCs 1 hour days, number viable counted...
Age-related macular degeneration (AMD) is a major cause of blindness in the elderly. Previous sequencing studies AMD susceptibility genes have revealed association rare coding variants CFH, CFI, C3 and C9 European population; however, impact or low-frequency on other populations largely unknown. To identify role exudative Japanese population, we analysed 34 candidate two-stage design by multiplex PCR-based target method. We used total 2,886 (1st: 827, 2nd: 2,059) cases including typical AMD,...
To evaluate the 1-year visual outcomes and anatomic responses of Japanese patients who received intravitreal brolucizumab (IVBr) injections for polypoidal choroidal vasculopathy (PCV). This was a retrospective study 17 treatment-naïve eyes with PCV that were treated IVBr. We evaluated best-corrected acuity (BCVA), central macular thickness (CMT), (CCT) number 1 year. The eradication lesions also using by indocyanine green angiography during follow-up. Non-infectious intraocular inflammation...