- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Screening and Detection
- Diverticular Disease and Complications
- Gastric Cancer Management and Outcomes
- Enhanced Recovery After Surgery
- Genetic factors in colorectal cancer
- Hernia repair and management
- Pelvic and Acetabular Injuries
- COVID-19 and healthcare impacts
- Appendicitis Diagnosis and Management
- Gastrointestinal Tumor Research and Treatment
- Stoma care and complications
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Oral Health Pathology and Treatment
- Central Venous Catheters and Hemodialysis
- Acute Myocardial Infarction Research
- Anesthesia and Pain Management
- Venous Thromboembolism Diagnosis and Management
- Mycobacterium research and diagnosis
York Teaching Hospital NHS Foundation Trust
2011-2024
Western Health
2023
Scarborough General Hospital
2010-2022
University of Liverpool
2021
Countess of Chester Hospital NHS Foundation Trust
2021
Royal London Hospital
2021
King's College London
2021
Chesterfield Royal Hospital NHS Foundation Trust
2020
Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust
2020
Dorset County Hospital NHS Foundation Trust
2020
This study was designed to examine the natural history of subclinical leaks and their effect on bowel function quality life evaluate water-soluble contrast enema features that predict anastomotic healing after leaks.Consecutive patients who underwent low rectal anastomosis were followed up postoperatively for leaks. All confirmed radiologically with CT scanning imaging. Water-soluble enemas serially repeated identify healing. Characteristics initial correlated observed Postoperatively,...
Purpose: We studied preoperative and perioperative factors with particular attention to the role of immunomodulatory medication, which may impact incidence pouch-related septic complications. Methods: A retrospective review data from patients who underwent ileal pouch surgery during a 20-year period 1985 2005 was performed. Preoperative use medication along clinical, surgical, disease variables were recorded. Patients monitored for sepsis in early (within 30 days surgery) late (after...
Urogenital prolapse is relatively common compared with rectal and the combination of urogenital still more infrequent. This study was designed to evaluate functional outcome a series patients who have undergone open mesh sacrocolporectopexy surgery for combined vaginal prolapse.Consecutive from June 2000 2004 confirmed subsequently underwent sacrocolporectopexy. The Cleveland Clinic Short Form-20 Pelvic Floor Distress Inventory questionnaire Urinary Inventory, Organ Prolapse Colorectal-Anal...
Intra-anal injectable agents have been used to treat faecal incontinence. The aim of this study was report the experience a cohort patients who underwent intra-anal injection collagen and determine which benefited from technique.Data, including age, sex, incontinence score, classification incontinence, baseline resting pressure vector volume, were collected prospectively for 73 consecutive (59 women) undergoing injection. Patients reviewed after treatment scores documented. A proportion also...
Faecal incontinence is a socially disabling condition that affects heterogeneous population of patients. There no standardization investigations, and treatment outcomes are variable. The major limitation for comparing the results from different studies lack pretreatment classification incontinence. aim this study was to review anorectal investigation findings propose simple, repeatable faecal incontinence.Patients who had investigations defaecatory disorders February 2000 September 2006 were...
PURPOSE: Previous studies on dysbiosis and pouchitis using conventional culture techniques have been disappointing because of inherent limitations associated with the technique. This study was designed to use terminal restriction fragment length polymorphism evaluate patients without pouchitis. METHODS: Bacterial microbiota in 20 pouch (15 healthy 5 inflamed) were studied. DNA extracted from feces, polymerase chain reaction performed primers (V6–V8 region) that modified at 5′ end cyanine...
BACKGROUND: The St. Mark's score and Cleveland Clinic are widely used for assessing the severity of fecal incontinence, whereas Rockwood quality life scale is to evaluate impact on patients. OBJECTIVE: aim this study was determine intra- interobserver reliability these assessment tools. DESIGN: All patients were recruited prospectively. To assess intraobserver each patient asked complete 4 assessments (the scores, scale, a visual analog scale) at 2 time points: initially recruitment (P1)...
Faecal incontinence is a distressing condition that can result in significant embarrassment and limitation of routine activities. General practitioners (GP) are the primary carers such patients. There recent developments surgical treatment options for this under-reported condition. Awareness these changes required to make best use them. To knowledge authors, no studies have examined awareness investigations faecal amongst GPs. This focus our study.A confidential questionnaire was posted GPs...
Therapeutic angiography with embolization is fast becoming the preferred treatment modality for major bleeding in lower gastrointestinal (LGI) tract. The aim of this study was to determine long term outcome and complications percutaneous coil (PCE) its efficacy as definitive therapy patients LGI bleeding.All presenting our institution a haemodynamically significant tract bleed between 1995 2001 that were unresponsive conservative measures considered emergency where appropriate. these...
Pouchitis is a common complication after ileal pouch-anal anastomosis. Diagnosis based on the Pouch Disease Activity Index, which comprises clinical symptoms, endoscopic appearance, and histologic confirmation. A Index > or = 7 confirms pouchitis. Fecal lactoferrin marker of intestinal inflammation, can aid in diagnosis The IBD EZ VUE test simple, rapid, noninvasive for fecal lactoferrin. Our goal was to study sensitivity specificity this pouchitis.Consecutive patients with pouch dysfunction...
Anorectal manometry is commonly used to investigate fecal incontinence. Traditional practice dictates that measurements are performed with the patient in left-lateral position however, episodes of incontinence usually occur erect position. The influence posture on anorectal has not been studied.We examined contribution measured variables during by performing assessment and posture. Maximum mean resting pressure, vector volumes, pressure gradient were compared.Complete data available for 172...
Neoadjuvant chemotherapy may have a role in the management of colonic carcinoma but clinical trials are required to determine whether this approach is superior standard policy radical surgery, high-quality histopathology and selective postoperative chemotherapy. The selection appropriate patients for such will depend on accurate locoregional staging disease by preoperative CT scanning. We studied outcome after right hemicolectomy assessed accuracy scans prediction pathology.A retrospective...
Fecal lactoferrin is a marker of intestinal inflammation and can be assessed with simple qualitative immunochromatographic rapid test.We aimed to assess the sensitivity specificity test in diagnosis pouchitis evaluate its clinical utility surveillance pouch after antibiotic therapy.Between October 2005 September 2009, we recruited consecutive series patients who had their ileal examined under general anesthetic. Distinctions between healthy inflamed pouches were made by use Pouch Disease...
Anismus is a functional disorder featuring obstructive symptoms and paradoxical contractions of the pelvic floor. This study aims to establish diagnosis agreement between physiology radiology, associate anismus with morphological outlet obstruction, explore role sphincteric pressure rectal volumes in radiological anismus.Consecutive patients were evaluated by using magnetic resonance imaging proctography/fluoroscopic defecography anorectal physiology. Morphological features associated tests....
Background Colorectal cancer is the second most common type of solid organ in New Zealand behind prostate cancer. Even with treatment, distant disease may develop liver and lungs. Surgical resection isolated and/or lung metastasis now commonly considered, but survival outcomes from latter are not well described. This study aims to review 5-year prognostic factors patients who have for colorectal origin. Methods A retrospective audit surgical performed by thoracic departments several tertiary...
The aim of this study was to investigate the effect a Post Acute Respiratory Outreach Service (PAROS) for patients with chronic obstructive pulmonary disease (COPD), on hospital utilization.A retrospective cohort examined, using nested comparison, test hypothesis that PAROS would affect utilization in 12 months following intervention. Patients admitted COPD and subsequently enrolled were compared age, sex diagnosis-matched controls COPD, who did not receive PAROS.Of 216 during 1-year period,...
By convention, a total obstruction of the coronary artery with no flow at occluded segment that has been present for least 3 months is termed as chronic occlusion or CTO. This to be distinguished from sudden lumen by thrombus during an acute myocardial infarction. Percutaneous intervention (PCI) CTO increasingly being performed interventional cardiologists improved success rates. In this article, focus will on antegrade techniques assist operator maximise rates and minimise complications.