Nasmille L. Larke-Mejía

ORCID: 0000-0003-4287-0699
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About
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Research Areas
  • Microbial Community Ecology and Physiology
  • Microbial Metabolic Engineering and Bioproduction
  • Microbial bioremediation and biosurfactants
  • Plant biochemistry and biosynthesis
  • Soil Carbon and Nitrogen Dynamics
  • Methane Hydrates and Related Phenomena
  • Genomics and Phylogenetic Studies
  • Pesticide and Herbicide Environmental Studies
  • Analytical Chemistry and Chromatography
  • Fungal and yeast genetics research
  • Fermentation and Sensory Analysis
  • Microbial metabolism and enzyme function
  • Isotope Analysis in Ecology
  • Plant Pathogens and Fungal Diseases
  • Metabolomics and Mass Spectrometry Studies
  • Gut microbiota and health
  • Plant and animal studies
  • Algal biology and biofuel production
  • Evolution and Genetic Dynamics
  • Pharmaceutical and Antibiotic Environmental Impacts

Norwich Research Park
2018-2024

Quadram Institute
2024

Ben-Gurion University of the Negev
2024

Earlham Institute
2023

University of East Anglia
2017-2020

Microbial ecology provides insights into the ecological and evolutionary dynamics of microbial communities underpinning every ecosystem on Earth. can now be investigated in unprecedented detail, although there is still a wealth open questions to tackled. Here we identify 50 research fundamental importance science or application ecology, with intention summarising field bringing focus new avenues. Questions are categorised seven themes: host-microbiome interactions; health infectious...

10.1093/femsec/fix044 article EN FEMS Microbiology Ecology 2017-03-31

The climate-active gas isoprene (2-methyl-1,3-butadiene) is released to the atmosphere in huge quantities, almost equaling that of methane, yet we know little about biological cycling environment. Although bacteria capable growth on as sole source carbon and energy have previously been isolated from soils sediments, no microbiological studies targeted major examined phyllosphere isoprene-emitting trees for presence degraders this abundant source. Here, identified isoprene-degrading poplar...

10.1073/pnas.1812668115 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2018-11-29

Isoprene is a climate-active gas and one of the most abundant biogenic volatile organic compounds (BVOC) released into atmosphere. In terrestrial environment, plants are primary producers isoprene releasing between 500-750 million tonnes per year to protect themselves from environmental stresses such as direct radiation, heat reactive oxygen species. While many studies have explored production, relatively little known about consumption by microbes well-characterized degrader Rhodococcus...

10.3389/fmicb.2019.02700 article EN cc-by Frontiers in Microbiology 2019-12-06

Approximately 500 Tg of isoprene are emitted to the atmosphere annually, an amount similar that methane, and despite its significant effects on climate, very little is known about biological degradation in environment. Isolation characterisation degraders at molecular level has allowed development probes targeting isoA encoding α-subunit monooxygenase. This enzyme belongs soluble diiron centre monooxygenase family catalyses first step pathway. The use key metabolic genes a successful...

10.1186/s40168-018-0607-0 article EN cc-by Microbiome 2018-12-01

Plant-produced isoprene (2-methyl-1,3-butadiene) represents a significant portion of global volatile organic compound production, equaled only by methane. A metabolic pathway for the degradation was first described Gram-positive bacterium Rhodococcus sp. AD45, and an alternative model organism has yet to be characterised. Here, we report characterisation novel Gram-negative isoprene-degrading bacterium, Variovorax WS11. Isoprene metabolism in this involves plasmid-encoded iso gene cluster...

10.3390/microorganisms8030349 article EN cc-by Microorganisms 2020-02-29

Isoprene is a climate-active gas whose wide-spread global production stems mostly from terrestrial plant emissions. The biodegradation of isoprene carried out by number different bacteria wide range environments. This study investigates the genome novel degrading bacterium Nocardioides sp. WS12, isolated soil associated with Salix alba (Willow), tree known to produce high amounts isoprene. WS12 was fully sequenced, revealing presence complete monooxygenase gene cluster, along degradation...

10.3390/microorganisms8060889 article EN cc-by Microorganisms 2020-06-12

The volatile secondary metabolite, isoprene, is released by trees to the atmosphere in enormous quantities, where it has important effects on air quality and climate. Oil palm trees, one of highest isoprene emitters, are increasingly dominating agroforestry over large areas Asia, with associated uncertainties their Microbes capable using as a source carbon for growth have been identified soils tree phyllosphere, most members Actinobacteria. Here, we used DNA stable isotope probing identify...

10.3390/microorganisms8101557 article EN cc-by Microorganisms 2020-10-10

Abstract Background Microbial methane oxidation, methanotrophy, plays a crucial role in mitigating the release of potent greenhouse gas from aquatic systems. While aerobic methanotrophy is well-established process oxygen-rich environments, emerging evidence suggests their activity hypoxic conditions. However, adaptability these methanotrophs to such environments has remained poorly understood. Here, we explored genetic hypoxia methanogenic sediments Lake Kinneret (LK). These LK sediments,...

10.21203/rs.3.rs-3790875/v1 preprint EN cc-by Research Square (Research Square) 2024-04-18

Abstract Background Microbial methane oxidation, methanotrophy, plays a crucial role in mitigating the release of potent greenhouse gas from aquatic systems. While aerobic methanotrophy is well-established process oxygen-rich environments, emerging evidence suggests their activity hypoxic conditions. However, adaptability these methanotrophs to such environments has remained poorly understood. Here, we explored genetic hypoxia methanogenic sediments Lake Kinneret (LK). These LK sediments,...

10.1186/s40793-024-00586-1 article EN cc-by Environmental Microbiome 2024-07-02

Mycena citricolor is a fungus that causes the American Leaf Spot (ALS) disease in multiple hosts, including coffee and avocado. This hemibiotroph penetrates plant through damage induced by oxalic acid. can cause 20-90% crop losses depending on environmental production conditions. M. only known pathogenic species genus, large group of saprophytic mushrooms. Comparing genomes allow us to identify genetic machinery associated with pathogen's genome-wide functional acquisitions disease. To...

10.1101/2023.12.30.573698 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-12-30
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