A5064301562- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Autism Spectrum Disorder Research
- Cancer Research and Treatments
- Cancer Treatment and Pharmacology
- Virus-based gene therapy research
- Medical Imaging Techniques and Applications
- Child Development and Digital Technology
- Immunotherapy and Immune Responses
- Meningioma and schwannoma management
- Adenosine and Purinergic Signaling
- Nanoplatforms for cancer theranostics
- Obsessive-Compulsive Spectrum Disorders
- Management of metastatic bone disease
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- RNA Interference and Gene Delivery
- Neurological Complications and Syndromes
- Cancer-related cognitive impairment studies
- Behavioral and Psychological Studies
- Histone Deacetylase Inhibitors Research
- Face Recognition and Perception
- CAR-T cell therapy research
- MRI in cancer diagnosis
- Neurofibromatosis and Schwannoma Cases
University of Michigan
2003-2025
Michigan Medicine
2022
Beaumont Hospital, Royal Oak
2019
A. Alfred Taubman Health Care Center
2019
American Academy of Child and Adolescent Psychiatry
2019
Columbia University
2013-2019
Curtin University
2013-2014
University of Alabama at Birmingham Hospital
2014
Henry Ford Hospital
2014
2019 Background: This is the initial report on a first in human Phase I dose escalation trial of combination two adenoviral vectors expressing HSV1-TK or Flt3L for treatment newly diagnosed, resectable malignant gliomas. The absence functional dendritic cells from brain precludes anti-brain tumor immune responses. We combined cytotoxicity (Ad-HSV1TK) with recruitment to (Ad-Flt3L) induce an effective anti-tumor response. strategy induced efficacious, cytotoxic CD8 and CD4 T-dependent...
CNS metastases are associated with decreased survival and quality of life for patients metastatic breast cancer (MBC). Team-based care can optimize outcomes. IMPACT the Brain is a coordination program that aims to improve access team-based MBC metastases.Patients were eligible enrollment in this program. A team specialists supported dedicated coordinator who provided navigation, education, specialty referral, clinical trial screening. unique intake form developed created personalized,...
Abstract Management of venous thromboembolism (VTE) in patients with primary and metastatic brain tumors (BT) is challenging because the risk intracranial hemorrhage (ICH). There are no prospective clinical trials evaluating safety efficacy direct oral anticoagulants (DOACs), specifically BT, but they widely used for VTE this population. A group neuro‐oncology experts convened to provide practical guidance off‐label use DOACs treating BT. We searched PubMed following terms: BTs, glioma,...
Prognostic factors of stroke-like migraine attacks after radiation therapy (SMART) syndrome have not been fully explored. This study aimed to assess clinical and imaging features predict the outcome SMART syndrome.We retrospectively reviewed manifestations findings 20 patients with (median age, 48 years; 5 women) from January 2016 2020 at 4 medical centers. Patient demographics MR time diagnosis were reviewed. cohort was divided into 2 groups based on degree improvement (completely versus...
We report a case of prolonged survival in patient with known cervical intramedullary H3K27M-mutant diffuse midline glioma. A 39-year-old man presented for evaluation several months progressive upper extremity pain and weakness. MRI the spine revealed an ring-enhancing lesion centred at C3-C4. Following subtotal surgical resection, diagnosis glioblastoma (GBM) was confirmed. Subsequent testing later date H3K27M mutation. He initially treated radiation concomitant adjuvant temozolomide. had...
Objective: While local bias in visual processing children with autism spectrum disorders (ASD) has been reported to result difficulties recognizing faces and facially expressed emotions, but superior ability disembedding figures, associations between these abilities within a group of without ASD have not explored. Methods: Possible performance on the Visual Perception Skills Figure–Ground test, face recognition test an emotion were investigated 25 8–12-years-old high-functioning...