- Viral gastroenteritis research and epidemiology
- Child Nutrition and Water Access
- Hepatitis Viruses Studies and Epidemiology
- Public Health and Nutrition
- Congenital Anomalies and Fetal Surgery
- Viral Infections and Immunology Research
- Vaccine Coverage and Hesitancy
- Nosocomial Infections in ICU
- Animal Virus Infections Studies
- Child and Adolescent Health
- Healthcare Quality and Satisfaction
- Antibiotic Use and Resistance
- Breastfeeding Practices and Influences
- Streptococcal Infections and Treatments
- Respiratory viral infections research
- Neonatal and Maternal Infections
- Infection Control in Healthcare
- Child Nutrition and Feeding Issues
- Menstrual Health and Disorders
- Tuberculosis Research and Epidemiology
- Infant Nutrition and Health
- Malaria Research and Control
- Trace Elements in Health
- Clostridium difficile and Clostridium perfringens research
- Vitamin D Research Studies
Universitas Gadjah Mada
2016-2025
ADA University
2001-2022
Udayana University
2016
Rumah Sakit Umum Pusat Dr. Sardjito
2009-2015
Dr. Hasan Sadikin General Hospital
2010
Padjadjaran University
2010
Institute of Child Health
2008
A strategy of administering a neonatal rotavirus vaccine at birth to target early prevention gastroenteritis may address some the barriers global implementation vaccine.
Background Prevention of hospital-acquired infections (HAI) is central to providing safe and high quality healthcare. Transmission infection between patients by health workers, the irrational use antibiotics have been identified as preventable aetiological factors for HAIs. Few studies addressed this in developing countries. Aims To implement a multifaceted control antibiotic stewardship programme evaluate its effectiveness on HAIs use. Methods A before-and-after study was conducted over 27...
Primaquine is the only licensed drug for eradicating Plasmodium vivax hypnozoites and, therefore, preventing relapses of malaria. It a vital component global malaria elimination efforts. efficacious when supervised in clinical trials, but its effectiveness real-world settings unknown. We aimed to determine whether unsupervised primaquine was effective re-presentation hospital with southern Papua, Indonesia.Routinely-collected surveillance data were used undertake pragmatic comparison risk...
In Indonesia, oral rotavirus vaccines are available but not funded on the National Immunization Program (NIP). New immunization program introduction requires an assessment of community acceptance. For religiously observant Muslims in vaccine acceptance is further complicated by use porcine trypsin during manufacturing and absence halal labeling. religious leaders Majelis Ulama Indonesia (MUI) important resources for many decisions regarding medicines, including vaccines. This study aimed to...
Background Malaria control activities can have a disproportionately greater impact on Plasmodium falciparum than P. vivax in areas where both species are coendemic. We investigated temporal trends malaria-related morbidity and mortality Papua, Indonesia, before after introduction of universal, artemisinin-based antimalarial treatment strategy for all species. Methods findings A prospective, district-wide malariometric surveillance system was established April 2004 to record cases malaria at...
Globally, rotavirus is the leading cause of diarrhea-related hospitalizations and deaths among young children, but burden disease in Indonesia poorly documented. From January through December 2006, we conducted prospective surveillance (inpatient outpatient) children aged <5 years at 6 hospitals provinces Indonesia, using standardized methodology. Of 2240 enrolled hospitalized for diarrhea, 1345 (60%) were positive. 176 outpatient clinics 3 hospitals, 73 (41%) Among dehydration was more...
Diarrhea is a major public health concern throughout the world because prevalence of morbidity diarrhea has not changed significantly in past decade. It remains third leading cause death among children less than 5 years age. Recent surveillance studies have shown that rotavirus significant pediatric hospitalization and due to diarrhea. Indonesia limited data on risk factors, disease burden, deaths The objective this study was examine above mentioned factors related hospitalized Sanglah...
Background Vitamin D deficiency has been associated with acute respiratory infection (ARI) in early life, but this not evaluated Indonesia. We aimed to determine the incidence of ARI Indonesian infants, and evaluate association vitamin deficiency. Methods From 23 December 2015 31 2017, we conducted a community-based prospective cohort study Yogyakarta province. enrolled 422 pregnant women followed their infants from birth until 12 months age for episodes. status was measured at six months....
Healthcare-associated infections (HAI) are one of significant causes morbidity and mortality. Evaluating risk factors associated with HAI important to improve clinical outcomes. We aimed evaluate the in children a low-to middle-income country.A prospective cohort study was conducted during 43 months at teaching hospital Yogyakarta, Indonesia. All consecutive patients admitted pediatric ICU wards > 48 h were eligible. Those eligible observed daily identify presence based on CDC criteria. The...
A longitudinal study of acute diarrhea in children Yogyakarta, Indonesia (June 1978 to June 1979), showed little variation throughout most months the year numbers admitted hospital and infected with rotaviruses. Both decreased during November December coincidentally seasonal change from dry wet conditions. Rotavirus particles were identified by electron microscopy fecal specimens 126 334 (38%) infants diarrhea. Nosocomial rotavirus infections occurred 11% control for other reasons....
Background Vitamin D deficiency in infants has been associated with an increased risk of a number diseases but there are limited data on the prevalence and determinants vitamin from tropical settings high infant morbidity mortality. Objective To determine at birth six months age Yogyakarta province, Indonesia. Design Serum eligible was measured cord blood age. Factors (serum 25-hydroxyvitamin <50 nmol/L) were collected prospectively monthly concentrations by liquid chromatography-tandem mass...
Abstract Background Studies have suggested that demographic and lifestyle factors could shape the composition of fecal microbiota in early life. This study evaluated infant stool signatures two Asian populations, Singapore (n = 42) Indonesia 32) with contrasting socioeconomic development, examined putative influences on these human associated bacterial signatures. Results Longitudinal analysis showed associations geographical origin Clostridium leptum, Atopobium Bifidobacterium groups. Mode...
Abstract Rotavirus vaccines are less effective in high mortality regions. A rotavirus vaccine administered at birth may overcome challenges to uptake posed by a complex gut microbiome. We investigated the association between microbiome and responses following RV3-BB (G3P[6]) neonatal schedule (dose 1: 0-5 days), or infant 6-8 weeks) Indonesia (Phase 2b efficacy study) ( n = 478 samples/193 infants) (ACTRN12612001282875) Malawi (Immunigenicity (n 355 samples/186 (NCT03483116). Vaccine...
To determine the prevalence of vitamin D deficiency in Indonesian children hospitalized with pneumonia and evaluate association between status severity pneumonia.A hospital-based cross-sectional study was conducted from February 2016 to July 2017 two district hospitals Yogyakarta province, Indonesia. Infants young aged 2-59 months were recruited. Serum blood samples collected on admission analyzed for total serum 25-hydroxyvitamin D3 D2 concentrations using liquid chromatography-tandem mass...
This research explores the aspects of ideal end life for older adults in Cianjur, with a specific focus on religious and cultural that shape perceptions practices surrounding this significant stage, using mixed-methods approach. The study involves 18 qualitative participants—consisting 9 their respective families—and 160 quantitative participants spread across West Java, Indonesia. specifically focuses Indonesian Sundanese Muslim population, exploring how beliefs traditions influence...
Rotavirus has been identified as the most common pathogen associated with severe diarrhoea. Two effective vaccines against have licensed. However, many countries including Indonesia yet to introduce vaccine into their national immunisation programs. This study aimed examine attitudes of healthcare providers (HCPs) and other health stakeholders towards vaccine. Semi-structured in-depth interviews were undertaken in two districts Yogyakarta Province, nurses, midwives, primary care providers,...
Rotavirus is the major cause of severe diarrhea in children under 5 years old developed and developing countries. Since improvements sanitation hygiene have limited impact on reducing incidence rotavirus diarrhea, implementation a vaccine will be better solution. We conducted an observational study to determine disease burden identify genotype circulating Indonesia. Hospitalized due acute were enrolled from four teaching hospitals Stool samples collected based WHO protocol tested for...
Background Anaemia in children under five years old is associated with poor health, growth and developmental outcomes. In Papua, Indonesia, where the burden of anaemia infants high, we conducted a community survey to assess association between Plasmodium infection, helminth carriage risk anaemia. Methods A cross sectional household was carried out April July 2013 16 villages District Mimika using multistage sampling procedure. total 629 aged 1–59 months from 800 households were included...