- Nutrition and Health in Aging
- Cardiovascular and exercise physiology
- Scoliosis diagnosis and treatment
- Body Composition Measurement Techniques
- Physical Activity and Health
- Gut microbiota and health
- Sports Performance and Training
- Cerebral Palsy and Movement Disorders
- Clostridium difficile and Clostridium perfringens research
- Muscle metabolism and nutrition
- Frailty in Older Adults
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Connective tissue disorders research
- Obesity, Physical Activity, Diet
- Adipose Tissue and Metabolism
- Smoking Behavior and Cessation
- Nutritional Studies and Diet
- Machine Learning in Healthcare
- Balance, Gait, and Falls Prevention
- Colorectal Cancer Screening and Detection
- Exercise and Physiological Responses
- Sports injuries and prevention
- Dietary Effects on Health
- Adipokines, Inflammation, and Metabolic Diseases
National Institute of Biomedical Innovation, Health and Nutrition
2018-2025
Juntendo University
2013-2024
National Institute of Infectious Diseases
2018-2022
Nihon University
2019
National Institutes of Health
2014
Juntendo University Hospital
2011
Abstract The phase angle (PhA), measured via bioelectrical impedance analysis, is considered an indicator of cellular health, where higher values reflect cellularity, cell membrane integrity, and better function. This study aimed to examine the relationship between PhA exercise habits or objectively physical activity. We included 115 people aged 32–69 years. body composition were using a device. Physical activity sedentary behavior (SB) assessed triaxial accelerometer. Exercise also obtained...
Inter-individual variations in gut microbiota composition are observed even among healthy populations. The may exhibit a unique depending on the country of origin and race individuals. To comprehensively understand link between host state, it is beneficial to conduct large-scale cohort studies. aim present study was elucidate integrated non-redundant factors associated with within Japanese population by 16S rRNA sequencing fecal samples questionnaire-based covariate analysis.A total 1596...
The National Health and Nutrition Survey consistently assesses the prevalence of exercise habits, step counts, sedentary behaviors in a strategically selected random sample Japanese population. aim this study was to provide descriptive epidemiological data on average frequency daily behavior among adults from 2003 2019 using database Japan. Data were obtained electronically available aggregate reports official survey website. To prepare for third term Japan 21, scheduled start 2024, we...
Abstract Objective In Japan, while it is known that underweight women over the age of 40 years have a high risk for type 2 diabetes, there lack clarity on association between glucose tolerance and in younger women. Accordingly, we investigate prevalence features impaired (IGT) young Japanese Designs Methods this cross-sectional study, recruited 56 normal weight 98 evaluated their levels using an oral test. Then, compared clinical characteristics associated with (NGT) IGT Insulin secretion,...
Abstract Background Low muscle strength has been focused on as an essential characteristic of sarcopenia, and the 30-s chair stand test (CS-30) could be a particularly useful for assessing strength. While it is speculated to beneficial tool assessment this remains verified. In study, we examined reliability optimal diagnostic score CS-30 sarcopenia in elderly Japanese participants. Methods This cross-sectional study included 678 participants (443 females 235 males) who underwent per Asian...
Many activity trackers have been developed, but steps can still be inconsistent from one monitor to another.What are the differences and associations between of 13 selected consumer-based research-grade wearable devices during 1 standardized day in a metabolic chamber 15-day free-living trials?In total, 19 healthy adults 21 50 years-old participated this study. Participants were equipped with 12 accelerometer-based active pedometer (Yamasa) order number per day. The worn on waist (ActiGraph,...
A lthough more than a year has passed since the first detection of coronavirus disease in Wuhan, China, it remains pandemic.Many governments have advocated for social distancing measures with varying degrees enforcement, ranging from unforced recommendations to business closures and city lockdowns.This induced sudden fundamental changes lifestyles populations.A study daily step counts January 19 June 1, 2020, measured using smartphones, found that count decreased March end May 2020 worldwide...
Introduction The gut microbiome plays a fundamental role in host homeostasis through regulating immune functions, enzyme activity, and hormone secretion. Exercise is associated with changes composition function. However, few studies have investigated the during training periodization. present study aimed to investigate relationship between periodization elite athletes. Methods In total, 84 athletes participated cross-sectional study; was determined their transition or preparation season...
Aim The gut microbiota has emerged as a new intervention target for sarcopenia. Prior studies in humans have focused on the association between and skeletal muscle quantity, while evidence function quality is lacking. This study aimed to identify genera associated with function, general population of Japanese adults. Methods cross‐sectional included 164 participants aged 35–80 years, women men recruited from urban areas Japan. Fecal samples were collected analyzed using 16S rRNA gene...
Objective The proportion of young Japanese women who are underweight is exceptionally high. We previously showed that the prevalence impaired glucose tolerance (IGT) was high in women, and IGT characterized by free fatty acid levels adipose tissue insulin resistance (ATIR). As next step, this study aimed to explore factors associated with elevated ATIR population. Participants Ninety-eight young, healthy, participated study. Design To investigate relationship between metabolic parameters,...
Abstract Fat-free mass (FFM) is a heterogeneous compartment comprising body cell (BCM), intracellular water (ICW), extracellular solids, and (ECW). The BCM/FFM ECW/ICW ratios vary among individuals decrease with age. This study aimed to determine whether are predictors of maximal oxygen uptake (V̇̇O2peak) independently age, sex, objectively measured physical activity (PA). A total 115 Japanese males females, aged 55.3 ± 8.0 years (mean standard deviation), were included in the study....
This study aimed to evaluate the association between locomotive syndrome (LS) and daily physical activity (PA) in community-dwelling older adults. cross-sectional included 80 healthy Japanese adults (40 men 40 women; age: 60-79 years). Habitual PA was evaluated using a triaxial wrist accelerometer. Participants were divided into two groups based on results of two-step test, stand-up 25-question geriatric function scale. Binomial logistic regression analysis conducted examine statistical...
Dietary plant lignans are converted inside the gut to enterolignans enterodiol (ED) and enterolactone (EL), which have several biological functions, health benefits. In this study, we characterized microbiome composition associated with enterolignan production using data from a cross-sectional study in Japanese population. We identified producers by measuring ED EL levels subject's serum liquid chromatography-tandem mass spectrometry. Enterolignan show more abundant proportion of...
Locomotive syndrome (LS) is associated with weakness and loss of function in the musculoskeletal organs. We aimed to determine association between LS components blood parameters middle-aged elderly individuals.We included 223 individuals this study (104 men 119 women; age: 40-85 years). All participants were asked fast for at least 3 h before venous samples obtained hemoglobin, total protein, glycated hemoglobin (HbA1c), growth hormone, albumin lipid profile measured. Three functional tests,...
As a low-carbohydrate diet and the use of sodium-glucose transporter-2 inhibitors are both known to increase D-beta-hydroxybutyrate levels, effect these levels on glucose metabolism has attracted attention. We investigated acute effects ketone monoester (KM) ingestion blood during 75-g oral tolerance test (OGTT) in participants with impaired tolerance.
This study determined the relationship between intra-individual variability in day-to-day nutrition-related lifestyle behaviors (meal timing, eating window, food intake, movement behaviors, sleep conditions, and body weight) glycemic outcomes under free-living conditions adults without type 2 diabetes.We analyzed 104 diabetes. During 7-day measurement period, dietary glucose were assessed. Daily intake was assessed using a mobile-based health application. Movement tri-axial accelerometer....
The benefit of body weight resistance exercise with slow movement (BWRE-slow) for muscle function is well-documented, but not energy metabolism. We aimed to examine physiological responses [e.g., expenditure (EE), respiratory exchange ratio (RER), and blood lactate (La)] during after BWRE-slow compared EE-matched treadmill walking (TW). Eight healthy young men (23.4 ± 1.8 years old, 171.2 6.2 cm, 63.0 4.8 kg) performed squat, push-up, lunge, heel-raise, hip-lift, crunch exercises modality....
Abstract Objective This study aimed to determine the effects of different energy loads on gut microbiota composition and rates nutrient excretion via feces urine. Method s A randomized crossover dietary intervention was conducted with three conditions: overfeeding (OF), control (CON), underfeeding (UF). Ten healthy men were subjected each condition for 8 days (4 3 nights in nonlaboratory laboratory settings each). The conditions urine assessed using a bomb calorimeter. Results Short‐term...
Abstract Background There are now many different types of activity trackers, including pedometers and accelerometers, to estimate step counts per day. Previous research has extensively examined step-count measurements using trackers across various settings while simultaneously wearing devices.; however, older adults frequently display distinct walking patterns gait speeds compared younger adults. This study aimed compare the between by having them wear seven in free-living experiments....
Previous cross-sectional studies have indicated that low relative appendicular lean mass (ALM) against body weight (divided by weight, ALM/Wt, or divided index, ALM/BMI) was negatively associated with metabolic syndrome (MetS). Conversely, previous the absolute ALM squared height (ALM/Ht2) were positively MetS. The aim of this longitudinal study to investigate association between skeletal muscle mass, leg power, percent fat and development MetS in Japanese women a 7-y prospective study....
Abstract Background Previous epidemiological studies have demonstrated the prevalence and relationship of various factors associated with sarcopenia in older adults; however, few examined status middle-aged adults. In this study, we aimed to, 1) evaluate validity finger-circle test, which is potentially a useful screening tool for sarcopenia, 2) determine Methods We conducted face-to-face surveys 525 adults, who were aged 40–91 years resided Settsu City, Osaka Prefecture, Japan to test. The...
Background and objectives: The purpose of this study was to compare the energy expenditures (EE) a single sit-to-stand (STS) movements with slow normal speeds using multi-stage exercise test. Materials Methods: Twelve young males, aged 21⁻27 years (age, 23.0 ± 1.7 years; height, 171.2 6.1 cm; weight, 64.3 5.6 kg), performed repeated 3-s stand-up sit-down (slow) or 1-s (normal) movement on two different days random order. All participants completed tests at STS frequencies per minute. slope...