A5022147892- Exercise and Physiological Responses
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Sports Performance and Training
- Muscle Physiology and Disorders
- Genetics and Physical Performance
- Sports injuries and prevention
- Physical Activity and Health
- Nutrition and Health in Aging
- Muscle activation and electromyography studies
- Obesity, Physical Activity, Diet
- Cardiovascular Effects of Exercise
- Children's Physical and Motor Development
- High Altitude and Hypoxia
- Scoliosis diagnosis and treatment
- Heart Rate Variability and Autonomic Control
- Body Composition Measurement Techniques
- Cerebral Palsy and Movement Disorders
- Spaceflight effects on biology
- Thermoregulation and physiological responses
- Heat shock proteins research
- Prosthetics and Rehabilitation Robotics
- Connective tissue disorders research
- Balance, Gait, and Falls Prevention
Juntendo University
2016-2025
Fujita Health University Hospital
2024
Nagoya University
2007-2023
Kanazawa University
2014-2022
Juntendo University Hospital
2007-2022
Advanced Research Institute
2021
Doshisha University
2020
Suzuki (Japan)
2020
The Open University of Japan
2016-2019
National Hospital Organization Mito Medical Center
2019
This study tested the hypothesis that elevation of heat stress proteins by whole body hyperthermia is associated with a decrease in skeletal muscle atrophy induced reduced contractile activity (i.e. , hindlimb unweighting). Female adult rats (6 mo old) were assigned to one four experimental groups (n = 10/group): 1) sedentary control (Con), 2) (Heat), 3) unweighting (HLU), or 4) before (Heat+HLU). Animals Heat and Heat+HLU exposed 60 min (colonic temperature approximately 41.6 degrees C)....
Experimental studies examining the effects of regular exercise on cardiac responses to ischemia and reperfusion (I/R) are limited. Therefore, these experiments examined endurance training myocardial biochemical physiological during in vivo I/R. Female Sprague-Dawley rats (4 mo old) were randomly assigned either a sedentary control group or an group. After 10-wk program, animals anesthetized mechanically ventilated, chest was opened by thoracotomy. Coronary occlusion achieved ligature around...
These experiments examined the independent effects of short-term exercise and heat stress on myocardial responses during in vivo ischemia-reperfusion (I/R). Female Sprague-Dawley rats (4 mo old) were randomly assigned to one four experimental groups: 1) control, 2) 3 consecutive days treadmill [60 min/day at 60–70% maximal O 2 uptake (V˙o max )], 3) 5 (60 60–70%V˙o ), 4) whole body (15 min 42°C). Twenty-four hours after or exercise, animals anesthetized mechanically ventilated, chest was...
The combined effects of aging and regular physical exercise was investigated on the production reactive oxygen species (ROS), lipid peroxidation, glutathione status, activity nuclear factor-kappaB (NF-kappaB) in rat liver. A group 24 male F344 rats divided into following categories: adult control (18 months), exercised aged (28 months) months). ROS formation increased as a function age training decreased rate two groups. Significant positive correlation found between peroxidation (LIPOX)....
The purpose of the present study was to investigate whether duration static stretching could affect maximal voluntary contraction (MVC). Volunteer male subjects (n = 10) underwent 2 different durations their hamstring muscles in dominant leg: 30 and 60 seconds. No condition used as a control condition. Before after each trial, flexibility measured by sit reach test. MVC then using effort knee flexion. significantly increased seconds (control: 0.5 +/- 1.1 cm; seconds: 2.1 1.8 3.0 1.6 cm);...
It is well known that various stimuli, such as mechanical stress and nutrients, induce muscle hypertrophy thorough the Akt/mTOR signalling pathway, which a key mediator of protein synthesis in skeletal muscle. was recently reported heat also induces an increase weight content. In addition, enhances after one bout resistance exercise. However, it remains unclear whether increased temperature itself stimulates pathway.Forty-two male Wistar rats (279.5 ± 1.2 g) were divided into control group...
Purpose Low-load voluntary exercise can induce muscle hypertrophy and strength gain in working muscles when combined with blood flow restriction (BFR). However, it is unknown whether such be induced by involuntary contractions triggered via low-intensity neuromuscular electrical stimulation (NMES) BFR. The purpose of this article was to investigate NMES BFR (NMES-BFR) could elicit the quadriceps. Methods Eight untrained young male participants (mean ± SE; age, 26.2 0.7 yr; height, 1.74 0.02...
Lactococcus lactis JCM 5805 (LC-Plasma) is a unique lactic acid bacteria (LAB) which activates plasmacytoid dendritic cells (pDC). We aimed to evaluate the effect of LC-Plasma on cell (DC) activity and subjective indices upper respiratory tract infections (URTI) fatigue in athletes under high intensity exercise. conducted randomized, placebo-controlled, double-blinded trial. Fifty-one male subjects belonging university sports club were randomized into placebo (n = 25) 26) groups. Individuals...
Type 2 Diabetes (T2D) is an emerging public health problem in Asia. Although ethnic specific mtDNA polymorphisms have been shown to contribute T2D risk, the functional effects of and therapeutic potential mitochondrial-derived peptides at are underexplored. Here, we showed Asian-specific mitochondrial DNA variation m.1382A>C (rs111033358) leads a K14Q amino acid replacement MOTS-c, insulin sensitizing peptide. Meta-analysis three cohorts (n = 27,527, J-MICC, MEC, TMM) show that males but not...
This study investigated the effects of exercise training duration on myosin heavy chain (MHC) isoform distribution in rat locomotor muscles. Female Sprague-Dawley rats (120 days old) were assigned to either a sedentary control group or one three endurance groups. Trained animals ran treadmill at approximately 75% maximal O2 uptake for 10 wk (4-5 days/wk) different durations (30, 60, 90 min/day). Training resulted increases (P < 0.05) citrate synthase activity soleus and extensor digitorum...
This study investigated the effect of heat stress (HS) on mammalian target rapamycin (mTOR) signaling involved in translation initiation after resistance exercise human skeletal muscle. Eight young male subjects performed four sets six maximal repetitions knee extension exercises, with or without HS, a randomized crossover design. HS was applied to belly vastus lateralis by using microwave therapy unit prior and during exercise. Muscle biopsies were taken from before, immediately after, 1 h...
Whereas single assessments of cardiorespiratory fitness have been shown to predict lower incidence type 2 diabetes, there are no data on long-term trends in and risk. We investigated the relationship between diabetes.A cohort 4,187 Japanese men free diabetes completed annual health checkups tests for estimated maximal oxygen uptake at least four times over 7 years (1979-1985). modeled trend each man using simple linear regression. Men were then divided into quartiles based regression...
This study was undertaken to investigate and compare the effects of proprioceptive neuromuscular facilitation (PNF) stretching static on maximal voluntary contraction (MVC). Thirteen male university students (age, 20 ± 1 years; height, 172.2 4.6 cm; weight, 68.4 6.7 kg; mean SD) completed 3 different conditions nonconsecutive days in randomized order: (SS), PNF (PNF), no (control, CON). Each condition consisted a 5-minute rest accompanied by one following activities: (a) control, (b) SS, or...
ABSTRACT Purpose Muscle injury is the most common sports injury. stiffness, a risk factor for muscle injury, lower in females than males, implying that sex-related genetic polymorphisms influence associated with stiffness. The present study aimed to clarify associations between two (rs2234693 and rs9340799) estrogen receptor 1 gene ( ESR1 ) or Methods In 1, questionnaire was used assess history of 1311 Japanese top-level athletes. 2, stiffness hamstring muscles assessed using ultrasound...