Haydar A. Demirel

ORCID: 0000-0003-3334-4793
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Exercise and Physiological Responses
  • Cardiovascular and exercise physiology
  • Muscle metabolism and nutrition
  • Adipose Tissue and Metabolism
  • Heat shock proteins research
  • Cardiovascular Effects of Exercise
  • Thermoregulation and physiological responses
  • Muscle Physiology and Disorders
  • Sports injuries and prevention
  • Spaceflight effects on biology
  • Galectins and Cancer Biology
  • Biochemical Acid Research Studies
  • Cardiac Ischemia and Reperfusion
  • Mitochondrial Function and Pathology
  • Sports Performance and Training
  • Hormonal Regulation and Hypertension
  • Coenzyme Q10 studies and effects
  • Stress Responses and Cortisol
  • High Altitude and Hypoxia
  • Cardiac electrophysiology and arrhythmias
  • Vitamin C and Antioxidants Research
  • Lower Extremity Biomechanics and Pathologies
  • Effects of Vibration on Health
  • Signaling Pathways in Disease
  • Neuroscience of respiration and sleep

Near East University
2025

Hacettepe University
2013-2023

University of Florida
1995-2002

Japan Research Institute
2001

Juntendo University
1997-2000

American College of Surgeons
1997-1999

Baylor College of Medicine
1999

University of Wisconsin–Madison
1996-1998

American Heart Association
1996-1998

Albert Einstein College of Medicine
1997

This study tested the hypothesis that elevation of heat stress proteins by whole body hyperthermia is associated with a decrease in skeletal muscle atrophy induced reduced contractile activity (i.e. , hindlimb unweighting). Female adult rats (6 mo old) were assigned to one four experimental groups (n = 10/group): 1) sedentary control (Con), 2) (Heat), 3) unweighting (HLU), or 4) before (Heat+HLU). Animals Heat and Heat+HLU exposed 60 min (colonic temperature approximately 41.6 degrees C)....

10.1152/jappl.2000.88.1.359 article EN Journal of Applied Physiology 2000-01-01

Experimental studies examining the effects of regular exercise on cardiac responses to ischemia and reperfusion (I/R) are limited. Therefore, these experiments examined endurance training myocardial biochemical physiological during in vivo I/R. Female Sprague-Dawley rats (4 mo old) were randomly assigned either a sedentary control group or an group. After 10-wk program, animals anesthetized mechanically ventilated, chest was opened by thoracotomy. Coronary occlusion achieved ligature around...

10.1152/ajpregu.1998.275.5.r1468 article EN AJP Regulatory Integrative and Comparative Physiology 1998-11-01

These experiments examined the independent effects of short-term exercise and heat stress on myocardial responses during in vivo ischemia-reperfusion (I/R). Female Sprague-Dawley rats (4 mo old) were randomly assigned to one four experimental groups: 1) control, 2) 3 consecutive days treadmill [60 min/day at 60–70% maximal O 2 uptake (V˙o max )], 3) 5 (60 60–70%V˙o ), 4) whole body (15 min 42°C). Twenty-four hours after or exercise, animals anesthetized mechanically ventilated, chest was...

10.1152/jappl.2001.91.5.2205 article EN Journal of Applied Physiology 2001-11-01

This study investigated the effects of exercise training duration on myosin heavy chain (MHC) isoform distribution in rat locomotor muscles. Female Sprague-Dawley rats (120 days old) were assigned to either a sedentary control group or one three endurance groups. Trained animals ran treadmill at approximately 75% maximal O2 uptake for 10 wk (4-5 days/wk) different durations (30, 60, 90 min/day). Training resulted increases (P < 0.05) citrate synthase activity soleus and extensor digitorum...

10.1152/jappl.1999.86.3.1002 article EN Journal of Applied Physiology 1999-03-01

Abstract Abundant evidence indicates that skeletal muscle plays a key role in regulating metabolic homeostasis. Therefore, maintaining healthy muscles is essential to good health. While prolonged inactivity known cause oxidative stress and loss, it remains unclear whether shift from an active sedentary lifestyle induces similar effects. This study tested the hypothesis transitioning rapidly leads loss load‐bearing soleus muscle. Adult Wistar rats were randomly divided into control (CON; n =...

10.1113/ep092331 article EN cc-by Experimental Physiology 2025-01-29

The effects of chronic exercise training on the expression heat shock protein (HSP) in skeletal muscle senescent animals are unknown. Therefore, purpose this study was to investigate HSP both young and old rats.Young adult (3 months) (23 female Fisher 344 rats were assigned either a sedentary control or an endurance trained group (N = 6 per group). Exercised ran (60 min.d-1, 5 d.wk-1) treadmill at approximately 77% VO2peak for 10 wk. After completion program, soleus (SOL), plantaris (PL),...

10.1097/00005768-200105000-00008 article EN Medicine & Science in Sports & Exercise 2001-05-01

Exercise training reduces myocardial lipid peroxidation following short-term ischemia-reperfusion.Med. Sci. Sports Exerc., Vol. 30, No. 8, pp. 1211-1216, 1998. Purpose: The purpose of these experiments was to test the hypothesis that endurance exercise will reduce ischemia and reperfusion(I-R). Methods: Female Sprague-Dawley rats (4 months old) were randomly assigned either a sedentary control group (N = 13) or an 13). trained animals ran 4 d·wk−1 (90 min·d−1) at ∼75% V˙O2max. Following...

10.1097/00005768-199808000-00005 article EN Medicine & Science in Sports & Exercise 1998-08-01

The purpose of these experiments was to examine the effects dietary antioxidant supplementation with vitamin E (VE) and α-lipoic acid (α-LA) on biochemical physiological responses in vivo myocardial ischemia-reperfusion (I-R) aged rats. Male Fischer-334 rats (18 mo old) were assigned either 1) a control diet (CON) or 2) VE α-LA supplemented (ANTIOX). After 14-wk feeding period, animals each group underwent an I-R protocol (25 min ischemia 15 reperfusion). During reperfusion, peak arterial...

10.1152/ajpregu.2000.279.6.r2149 article EN AJP Regulatory Integrative and Comparative Physiology 2000-12-01

Overexpression of heat shock protein (HSP)72 is associated with cardioprotection. Hyperthermia-induced HSP72 overexpression attenuated senescence. While exercise also increases myocardial in young animals, it unknown whether this effect aging. Therefore, we investigated the aging on exercise-induced factor (HSF)-1 activation and expression. Male Fischer-344 rats (6 or 24 mo) were randomized to control, exercise, hyperthermic groups. Exercise consisted 2 days treadmill running (60 min/day,...

10.1152/ajpheart.00982.2002 article EN AJP Heart and Circulatory Physiology 2003-10-01

Dietary supplements containing arginine are among the most popular ergogenics intended to enhance strength, power and muscle recovery associated with both anaerobic aerobic exercise.The aim of present study was evaluate possible effect pre-exercise acute intake on performance exercise metabolism during incremental exhaustive in elite male wrestlers.Nine volunteer wrestlers (24.7±3.8 years) participated this study.The test-retest protocol used same subjects.The conducted using a cross-over...

10.5604/20831862.1111436 article EN Biology of Sport 2014-07-01

We tested the hypothesis that chronic endurance exercise is associated with recruitment of four major upper airway muscles (genioglossus, digastric, sternohyoid, and omohyoid) results in an increased oxidative capacity a fast-toward-slow shift myosin heavy chain (MHC) isoforms these muscles. Female Sprague-Dawley rats (n = 8; 60 days old) performed treadmill exercises for 12 weeks (4 days/week; 90 minutes/day). Age-matched sedentary female 10) served as control animals. Training was increase...

10.1164/rccm.2104120 article EN American Journal of Respiratory and Critical Care Medicine 2002-08-01

Background: Gymnasts usually start intensive training from early childhood. The impact of such strenuous on the musculoskeletal system is not clear. Objectives: To evaluate relation between muscle strength ankle joint and foot structure in gymnasts. Methods: study population comprised 20 high level male gymnasts 17 non-athletic healthy controls. Arch indices were measured using a podoscope. Ankle plantar/dorsiflexion eversion/inversion strengths Biodex 3 dynamometer within protocol...

10.1136/bjsm.2004.011627 article EN British Journal of Sports Medicine 2005-02-23

This study examined whether the exercise-increased extracellular heat shock protein 72 (eHsp72) levels in rats was associated with body temperature elevation during exercise. In all, 26 female Sprague-Dawley (3 mo old) were assigned randomly to control (CON; n = 8), exercise under warm (WEx; 9), or cold (CEx; 9). The WEx and CEx trained at 25 degrees C 4 C, respectively, for nine days using a treadmill. Before immediately after final bout, colonic temperatures measured as an index of...

10.1152/ajpregu.00581.2007 article EN AJP Regulatory Integrative and Comparative Physiology 2008-03-27
Coming Soon ...