- Temporomandibular Joint Disorders
- Osteoarthritis Treatment and Mechanisms
- Muscle activation and electromyography studies
- Botulinum Toxin and Related Neurological Disorders
- Orthodontics and Dentofacial Orthopedics
- Facial Nerve Paralysis Treatment and Research
- Periodontal Regeneration and Treatments
- Bone health and osteoporosis research
- Dental Radiography and Imaging
- Oropharyngeal Anatomy and Pathologies
- Muscle Physiology and Disorders
- Facial Trauma and Fracture Management
- Adhesion, Friction, and Surface Interactions
- Dental materials and restorations
- Advanced Sensor and Energy Harvesting Materials
- Hand Gesture Recognition Systems
- Advanced Numerical Analysis Techniques
- Medical Imaging Techniques and Applications
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Motor Control and Adaptation
- Lower Extremity Biomechanics and Pathologies
- Dental Implant Techniques and Outcomes
- Dental Trauma and Treatments
- Advanced Neuroimaging Techniques and Applications
Academic Center for Dentistry Amsterdam
2014-2024
University of Amsterdam
2014-2024
Vrije Universiteit Amsterdam
2006-2023
Amsterdam UMC Location University of Amsterdam
2023
Smith College
2020
Syracuse University
2020
University of Rochester
2020
John Wiley & Sons (United States)
2020
Amsterdam UMC Location Vrije Universiteit Amsterdam
2011-2018
Tokushima University
2008
Follistatin-like 1 (Fstl1) is a secreted protein of the BMP inhibitor class. During development, expression Fstl1 already found in cleavage stage embryos and becomes gradually restricted to mesenchymal elements most organs during subsequent development. Knock down experiments chicken zebrafish demonstrated role as antagonist early To investigate mouse conditional KO allele well Fstl1-GFP reporter were created. mice die at birth from respiratory distress show multiple defects lung Also,...
The cartilaginous intra-articular disc of the human temporomandibular joint shows clear anteroposterior variations in its morphology. However, tissue behavior have not been investigated thoroughly. To test hypothesis that mechanical properties fresh discs vary direction, we performed dynamic indentation tests at three anteroposteriorly different locations. showed strong viscoelastic dependent on amplitude and frequency indentation, location, time. resistance against deformations shock...
The purpose of this study was to investigate the effects low-intensity pulsed ultrasound (LIPUS) stimulation on proliferation and differentiation cementoblast lineage cells.An immortalized human periodontal ligament cell line (HPL) showing immature cementoblastic used. Cultured HPL cells were subjected LIPUS exposure (frequency = 1 MHz; 1:4; intensity 30 mW/cm(2)) or sham for 15 minutes per day. Expression levels alkaline phosphatase (ALP), type I collagen (Col-I), runt-related gene 2...
Abstract Background/Aims There is a lack of data regarding the mechanical responses temporo‐mandibular joints during an impact to orofacial region. The aim this study was analyze biomechanical effects wearing mouthguard (MG) on response mandibular condyle and articular disk according type occlusion. hypothesis that MG would minimize effect in those structures, regardless occlusion type. Methods Using modeling software, human skull with jaw, teeth created. models were divided (Class I, II, or...
While the movability of human temporomandibular joint is great, strains and stresses in cartilaginous structures might largely depend on position mandible with respect to skull. This hypothesis was investigated by means static three-dimensional finite element simulations involving different habitual condylar positions. Furthermore, influence several model parameters examined sensitivity analyses. The results indicated that disc moved together condyle anterior direction without presence...
This study concerns the complex interaction between active muscle forces and passive guiding structures during jaw-closing movements. It is generally accepted that ligaments of joint play a major role in condylar guidance these While permit wide range motions, it was assumed they are not primarily involved force transmission joints. Therefore, hypothesized movement constraints caused by articular surfaces imply necessary sufficient condition to generate ordinary hypothesis tested...
To evaluate the accuracy and applicability of a commercially available microCT system for comparative measurements degree distribution mineralization developing bone.Homogeneous K2HPO4 solutions with different concentrations (range 0-800 mg/cm3) were used to assess equipped polychromatic X-ray source. Both high (45 kV) low (70 tube peak voltages explored. The resulting attenuation was compared calculated theoretical values estimate accuracy. As an example its applicability, method changes in...
Muscle force is proportional to the physiological cross-sectional area (PCSA), and muscle velocity excursion are fiber length. The length of sarcomeres a major determinant both velocity. goal this study was characterize architecture human pterygoid muscles evaluate possible functional consequences for For heads lateral medial pterygoid, bundles, PCSA, three-dimensional coordinates origin insertion points were determined. Measurements taken from eight cadavers, data used as input model...