A5076355516- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Analog and Mixed-Signal Circuit Design
- Cardiac Arrhythmias and Treatments
- Frailty in Older Adults
- Obstructive Sleep Apnea Research
- EEG and Brain-Computer Interfaces
- Atrial Fibrillation Management and Outcomes
- Geriatric Care and Nursing Homes
- Neuroscience of respiration and sleep
- Organizational Management and Innovation
- Dysphagia Assessment and Management
- Growth Hormone and Insulin-like Growth Factors
- Delphi Technique in Research
- Process Optimization and Integration
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Effects of Exercise
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cancer Treatment and Pharmacology
- Blood transfusion and management
- Advanced Manufacturing and Logistics Optimization
- Pleural and Pulmonary Diseases
Vall d'Hebron Hospital Universitari
2023
Institute for Bioengineering of Catalonia
2019-2021
Universitat Politècnica de Catalunya
2017-2021
Hospital Clínic de Barcelona
2016-2021
Instituto Tecnologico Del Embalaje, Transporte Y Logistica
2020-2021
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2020
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2015-2020
Inserm
2016-2018
Indra (Spain)
2018
Université de Rennes
2016-2018
Left atrial (LA) sphericity (LASP) is a new remodeling parameter based on LA shape analysis, with independent predictive value for recurrence after fibrillation (AF) ablation.To evaluate the association between LASP and thromboembolic events (TE) in patients AF.Twenty-nine AF prior TE 29 age- gender-matched controls were included. was calculated using 3D-LA reconstruction. The appendage (LAA) volume morphology assessed. ROC curve analysis performed LASP, volume, LAA CHAD/CHA2 D-VASc scores...
Electroanatomical mapping (EAM) systems are commonly used in clinical practice for guiding catheter ablation treatments of common arrhythmias. In focal tachycardias, the target is defined by locating earliest activation area determined joint analysis electrogram (EGM) signals at different sites. However, this currently a manual time-consuming and experience-dependent task performed during intervention thus prone to stress-related errors. paper, we present an automatic delineation strategy...
Background Home hospitalization is widely accepted as a cost-effective alternative to conventional for selected patients. A recent analysis of the home and early discharge (HH/ED) program at Hospital Clínic de Barcelona over 10-year period demonstrated high levels acceptance by patients professionals, well health value-based generation provider health-system levels. However, risk assessment was identified an unmet need with potential enhance clinical decision making. Objective The objective...
Ventricular arrhythmias in Brugada syndrome (BS) typically occur at rest and especially during sleep, suggesting that changes the autonomic modulation may play an important role arrhythmogenesis. The response to exercise subsequent recovery was evaluated on 105 patients diagnosed with BS (twenty-four were symptomatic), by means of a time-frequency heart rate variability (HRV) analysis, so as propose novel predictive model capable distinguishing symptomatic asymptomatic populations. During...
Symptoms such as ventricular arrhythmias in Brugada syndrome (BS) typically occur at rest, especially during sleep, suggesting that the autonomic nervous system (ANS) function may be relevant arrhythmogenesis of disease. The aim this work was to assess ANS response captured by nonlinear heart rate variability (HRV) measures 69 patients diagnosed with BS, who underwent a standardized physical stress test. Heart complexity (HRC) evaluated power-law scaling analysis (β slope) exercise, recovery...
Disability-Adjusted Life Years (DALYs) and Quality-Adjusted (QALYs), which capture life expectancy quality of the remaining life-years, are applied in a new method to measure socioeconomic impacts related health. A 7-step methodology estimating impact health interventions based on DALYs, QALYs functioning changes is presented. It relates latter (1) EQ-5D-5L questionnaire (2) automatically calculate status before after intervention (3). This change represented as when calculating gained due...
This paper describes the integration of mathematical models cardiac electrical activity, cardiovascular system and baroreceptor reflex control autonomic nervous system, with a model representing head-up tilt test. Sensitivity analyses are performed in order to determine those parameters producing greatest significant effects on heart rate blood pressure. An optimization step is then applied most influential find best fit real data obtained from patient suffering Brugada syndrome healthy...
This paper proposes the integration and analysis of a mathematical model representing cardiovascular system its short-term autonomic response to head-up tilt (HUT) testing. A Latin Hypercube Sampling method was applied design an optimal experimental space, including 19 parameters coming from baroreflex control systems. Then, global, variance-based sensitivity quantity effects these on heart rate systolic blood pressure. Results highlight relevant influence intrinsic sympathetic...
Implantable accelerometers have been already proposed for the continuous monitoring of heart wall motion.Although a number markers extracted from cardiac accelerometry associated with contractility, they are mainly based on uniaxial (1D) sensors, that not always reflect this relationship consistently.In work, 3Dacceleration signals obtained sensors located at left ventricle (LV) two anesthetized pigs were acquired baseline and during dobutamine infusion, along LV pressure.For each cycle,...
Home hospitalization (HH) is presented as a healthcare alternative capable of providing high standards care when patients no longer need hospital facilities. Although HH seems to lower costs by shortening stays and improving patient's quality life, the lack continuous observation at home may lead complications in some patients. Since blood tests have been proven provide relevant prognosis information many diseases, this paper analyzes impact different sampling methods on prediction outcomes....
Baroreflex sensitivity (BRS) is a valuable index to assess cardiovascular autonomic control and therefore provide prognostic evaluation in many cardiac diseases. Although several methods have been developed noninvasively capture spontaneous BRS, they are difficult compare often conflicting results. In this study we analyzed different BRS estimates obtained from clinical series of thirty-two patients diagnosed with Brugada syndrome. They took part standardized head-up tilt test order quantify...
Objective: Ventricular arrhythmias in Brugada syndrome (BS) mainly occur at rest, especially during nighttime, suggesting that parasympathetic activity night may play an important role the arrhythmogenesis of disease. This study examined and compared autonomic function symptomatic asymptomatic BS patients overnight. Approach: We analyzed various heart rate variability (HRV) complexity (HRC) markers a clinical series including 87 patients, where 23 were symptomatic. Main results:...
Hypoxia induced by obstructive sleep apnea (OSA) leads to the deregulation of autonomic nervous system (ANS), resulting in an abnormally increased sympathetic activity.Since ANS modulation varies throughout night, notably for each stage, hypnogram and heart rate signals 81 OSA patients were collected during a polysomnography.They classified as mild-moderate (n=44) or severe (n=37) based on their apnea-hypopnea index (AHI).Spectral variability (HRV) series extracted time-frequency...
Identifying high-risk patients requiring an ICD among asymptomatic Brugada is nowadays a bit challenging.In this study, 62 suffering from syndrome (14 symptomatic) were studied by analyzing the 12-lead ECG recording acquired during physical exercise test.For each patient, conventional HRV indices time-frequency analysis and heart rate recovery (HRV features), as well several morphological depolarization (QRS evaluated at relevant periods of test.Most discriminant features both QRS sets...
Calvo, C.; Hermida, R. Ayala, D. E.; Lopez, J. Dominguez, M. J.; Author Information
Cardiac events in Brugada syndrome (BS) usually occur at rest and mainly nighttime, commonly relating changes autonomic modulation to arrhythmogenesis.A major challenge today is differentiate symptomatic asymptomatic patients order optimize their therapy.Since assessment can be improved by the application of standard maneuveurs, this study analyzes compares response head-up tilt (HUT) testing on 20 45 BS patients.Their 12-lead ECG recordings were collected during a HUT test composed...
Abstract Background In addition to their lipid-lowering properties, statins possess cardioprotective effects. However, the impact of latter on acute cardioprotection and adverse left ventricular (LV) remodelling following ST-elevation myocardial infarction (STEMI) have not been investigated through cardiac magnetic resonance (CMR) analysis date. Purpose To investigate effects chronic oral statin treatment prior first STEMI. Methods The study included 1236 patients with a STEMI CMR performed...