A5055945854- Developmental Biology and Gene Regulation
- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Animal Behavior and Reproduction
- Invertebrate Immune Response Mechanisms
- Marine Ecology and Invasive Species
- Plant and animal studies
- Genomics and Phylogenetic Studies
- Lepidoptera: Biology and Taxonomy
- Genomics and Chromatin Dynamics
- Crustacean biology and ecology
- Plant Molecular Biology Research
- Silk-based biomaterials and applications
- Hemiptera Insect Studies
- CRISPR and Genetic Engineering
- RNA Research and Splicing
- Insect Resistance and Genetics
- Plant Reproductive Biology
- Animal Genetics and Reproduction
- Subterranean biodiversity and taxonomy
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic diversity and population structure
- Insect behavior and control techniques
- Cellular Mechanics and Interactions
- Marine and coastal plant biology
University of Chicago
2002-2025
Marine Biological Laboratory
2019-2025
University of Georgia
2025
University of California, Berkeley
2013-2022
Berkeley College
2011-2018
Acupuncture & Integrative Medicine College
2018
Integra (United States)
2005-2015
Howard Hughes Medical Institute
1999-2010
Mount Desert Island Biological Laboratory
2008
Utah State University
2008
We report the identification of a Drosophila locus, reversed polarity (repo). Weak repo alleles were viable but affected glia in optic lobe, resulting reversal electrophysiological to light adult. Strong caused defects embryonic and resulted lethality. Expression appeared be specific throughout development. In adult visual system, was expressed laminal glia, medullar subretinal cells; embryo, nearly all identified central peripheral nervous systems except midline glia. The gene encoded homeo...
In light of the current biodiversity crisis, DNA barcoding is developing into an essential tool to quantify state shifts in global ecosystems. Current protocols often rely on short amplicon sequences, which yield accurate identification biological entities a community but provide limited phylogenetic resolution across broad taxonomic scales. However, structure communities component biodiversity. Consequently, approach required that unites robust assignment power and high utility. A possible...
ABSTRACT Experimental investigations of eukaryotic enhancers suggest that multiple binding sites and trans-acting regulatory factors are often required for wild-type enhancer function. Genetic analysis the stripe 2 even-skipped (eve), an important developmental gene in Drosophila, provides support this view. Given importance expression early Drosophila development, it might be predicted many structural features will evolutionarily conserved, including DNA sequences protein spacing between...
MicroRNAs (miRNAs) are an extensive class of regulatory RNA whose specific functions in animals generally unknown. Although computational methods have identified many potential targets miRNAs, elucidating the spatial expression patterns miRNAs is necessary to identify sites miRNA action. Here, we report transcription during Drosophila embryonic development, as revealed by situ hybridization nascent transcripts. We detect 15 “stand-alone” loci and 9 intronic loci, which collectively represent...
Segment polarity genes in Drosophila are required for the proper formation of epidermal pattern within each segment. Here we show that certain segment also critical determination specific neuronal identities developing central nervous system (CNS) embryo. For several mutants, however, defects do not simply parallel their cuticular phenotypes. In fused, armadillo, and cubitus interruptus Dominant much CNS appears relatively normal. hedgehog is highly disorganized, but this disruption may...
ABSTRACT We have used a monoclonal antibody that recognizes engrailed proteins to compare the process of segmentation in grasshopper, crayfish, and Drosophila. Drosophila embryos rapidly generate metameres during an embryonic stage characterized by absence cell division. In contrast, many other arthropod embryos, such as those more primitive insects crustaceans, gradually sequentially, proliferation causes caudal elongation. all three organisms, pattern expression at segmented germ band is...
Antiserum against horseradish peroxidase (anti-HRP Ab) labels the surfaces of neurons in both Drosophila and grasshopper (Jan Jan, 1982). Here we show that anti-HRP Ab (1) immunoprecipitates at least 17 different membrane glycoproteins from embryo CNS (and a similar array grasshopper), (2) recognizes neural-specific carbohydrate moiety expressed by most if not all these proteins. Although stains axon pathways, 2 glycoproteins, fasciclin I II, are on specific subsets pathways embryo.
The amphipod crustacean Parhyale hawaiensis is a blossoming model system for studies of developmental mechanisms and more recently regeneration. We have sequenced the genome allowing annotation all key signaling pathways, transcription factors, non-coding RNAs that will enhance ongoing functional studies. member Malacostraca clade, which includes food crop species. analysed immunity related genes as an important comparative these species, where aquaculture problems increased farming has...