- Reproductive Biology and Fertility
- Vector-borne infectious diseases
- Reproductive System and Pregnancy
- Ovarian function and disorders
- Renal and related cancers
- Pluripotent Stem Cells Research
- Macrophage Migration Inhibitory Factor
- Pneumonia and Respiratory Infections
- Peptidase Inhibition and Analysis
- Travel-related health issues
- Enzyme Structure and Function
- Reproductive biology and impacts on aquatic species
- Thyroid Cancer Diagnosis and Treatment
- Radioactivity and Radon Measurements
- Prenatal Screening and Diagnostics
- Amoebic Infections and Treatments
- Tissue Engineering and Regenerative Medicine
- Plant tissue culture and regeneration
- Biochemical and Molecular Research
- Malaria Research and Control
- Fecal contamination and water quality
- Parasitic Infections and Diagnostics
- Polyamine Metabolism and Applications
- Genetic and Kidney Cyst Diseases
- Lipoproteins and Cardiovascular Health
Wuhan Children's Hospital
2024
Huazhong University of Science and Technology
2024
Boai Hospital of Zhongshan
2021-2024
Southern Medical University
2024
Hebei Normal University
2023
Tianjin Academy of Agricultural Sciences
2021
Ministry of Agriculture and Rural Affairs
2021
Inner Mongolia University
2020
Hospital for Tropical Diseases
2018
National Institute for Parasitic Diseases
2018
The goal of this study was to assess the association between endometrial thickness on chorionic gonadotropin (hCG) day and in vitro fertilization embryo transfer (IVF-ET) outcome normal responders after GnRH antagonist administration. A retrospective cohort performed with administration from January 2011–December 2013. Patients were divided into four groups according thickness, as follows: <7 mm (group 1), > = 7- < 8 2), 8- 14 3), =14 4). total 2106 cycles analyzed. pregnancy rate (PR)...
Introduction The Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder affecting women’s reproductive and metabolic health, faces diagnostic challenges due to heterogeneous clinical presentations the absence of reliable biomarkers. This study investigates role Glucosaminyl (N-acetyl) transferase 2 (GCNT2) in modulating sex hormone-binding globulin (SHBG) its potential as therapeutic target PCOS pathophysiology. Methods A prospective cohort 103 patients treated with oral...
China has initiated the National Malaria Elimination Action Plan, which aims to eliminate malaria by 2020. However, transmission of occurs sporadically or in distinct foci, greatly hampers progress toward elimination and other countries. The object this study was foci categorization evaluates whether response met requirements issued nation WHO.Residual transmissions were investigated located with fine spatial resolution mapping from parasitological confirmed cases use routine national...
MurAs (enolpyruvyl-UDP-GlcNAc synthases) from pathogenic bacteria such as Borrelia burgdorferi (Lyme disease) and tuberculosis are fosfomycin resistant because an Asp-for-Cys substitution prevents them being alkylated by this epoxide antibiotic. Previous attempts to characterize naturally Asp-containing have resulted in no protein or activity. We expressed characterized His-tagged Lyme disease MurA (Bb_MurA(H6)). The was most soluble at high salt concentrations but maximally active around...
The study was designed to investigate the effects of cryopreservation on bovine, ovine, and goat sperm motility, acrosome structure, enzyme activity, fertilization ability. Percentage with hyaluronidase (HYD) activity detected by a modified sodium hyaluronate-gelatin membrane. N-α-benzoyl-DL-arginine-p-nitroanilide (BNPNA) method used assess (ACE). mean percentage integrity dropped significantly (P < 0.01) after cryopreservation. ACE bovine (100.48) higher than that ovine (57.88) or (50.30),...
Pseudorabies (PR), the causative agent of Aujeszky's disease, has rapidly increased in recent years and caused significant economic losses. To understand seroprevalence epidemiological characteristics PR Tianjin, China, a total 23,627 blood 1,093 tissue samples were collected from 228 pig farms during January 2010 to December 2018. The virus (PRV) glycoprotein E (gE) antibody was tested by enzyme-linked immunosorbent assay (ELISA), wild-type PRV (WT PRV) detected gE-polymerase chain reaction...
The aim of the present study was to investigate mutational characteristics drug‑resistant genetic mutations in katG gene isoniazid (INH) multi‑drug resistant Mycobacterium tuberculosis (MTB) L‑form among patients with pneumoconiosis complicated (TB), order reduce occurrence drug resistance patients, and gain further insight into mechanisms underlying MDR‑TB L‑form. A total 114 clinically isolated strains MTB L‑forms were collected. identified using a conventional antimicrobial susceptibility...
Objectives: To identify the etiology and source after recognition of diarrhea outbreak is associated with drinking water in suburb Chengdu. Methods: Both unmatched case control retrospective cohort study were conducted. 131 targets including 56 suspected patients recruited for study, while 463 residents selected study. Stool, environmental samples collected laboratory testing. Results: The proportion exposed to well was 86% group compared 51% controls during epidemic period (OR = 6.14, P E....
Schistosomiasis is considered one of the most important neglected tropical diseases and remains a major public health problem in endemic countries. Toll-like receptor (TLR) ligands have been investigated as potential vaccine adjuvants for tumor virus immunotherapy. However, few TLR affecting schistosoma vaccines characterized. In this study, we evaluated TLR9 ligand (CpG oligodeoxynucleotide 1826, CpG) an adjuvant partially protective DNA encoding 26-kDa glutathione S-transferase Schistosoma...
Environmental pollution is an increasing problem in the world. The goal of present study was to carry out environmental assessment on pneumoconiosis through comprehensive analysis coal mine environment. dust Xinzhuangzi and Xiejiaji mines Huainan sampled characterize permissible concentration–short-term exposure limit concentration–time-weighted average. free SiO2 concentration determined by a pyrophosphate quality method. concentrations metals metalloids were atomic absorption spectrometry....
3-Deoxy-d- arabinoheptulosonate 7-phosphate (DAHP) oxime is a transition state mimic inhibitor of bacterial DAHP synthase, with K i = 1.5 μM and residence time tR 83 min. Unexpectedly, inhibition competitive respect to the essential metal ion, Mn2+, even though ion do not occupy same physical space in active site. This problematic because synthase activated by multiple divalent cations, some which have significant intracellular concentrations dissociate slowly. The nature oxime's competition...
Thyroid cancer ranks second in the incidence rate of endocrine malignant cancer. is usually asymptomatic at initial stage, which makes patients easily miss early treatment time. Combining genetic testing with imaging can greatly improve diagnostic efficiency thyroid Researchers have discovered many genes related to However, effects these on are different. We hypothesize that there a stronger interaction between core cause Based this hypothesis, we constructed an network cancer-related genes....
This study investigated whether RNA-Seq-based endometrial receptivity test (rsERT)-which provides precision for the optimal hour of window implantation (WOI)-can improve clinical outcomes frozen embryo transfer (FET) cycles in patients with a history repeated failure (RIF).